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c-Met protein overexpression and telisotuzumab vedotin efficacy by biopsy age, type, and region in the LUMINOSITY phase II study c-Met蛋白过表达及telisotuzumab vedotin疗效，根据LUMINOSITY II期研究中活检的年龄、类型和部位分析 Bar, J.; Baijal, S.; Luo, A.; Zhang, N.; Ratajczak, C.; Ansell, P. J.; Lu, S.; Camidge, D. R. 分享 收藏
Telisotuzumab vedotin (Teliso-V)-mediated c-Met internalization, endolysosomal trafficking, and potent cytotoxic activity are unaffected by MET exon-14 skipping mutation Batth, Izhar; Pandoy, Ronald; Khaja, Shamim; Maji, Dolonchampa; Uziel, Tamar; Vasilopoulos, Athan; Ansell, Peter; Epling-Burnette, P. K. 分享 收藏
Harness the power of real-world-data for oncology target and biomarker research: A case study by applying clinic-genomics data for 2,659 lung cancer patients and beyond Wu, Si; Zhao, Weilong; Choi, Christy; Cai, Mona; Ansell, Peter; Liede, Alexander; Chen, Rong; Zhao, Xi; Samayoa, Josue 分享 收藏
Prevalence, molecular characterization, and prognosis of METeoverexpressing non-small cell lung cancer (NSCLC) in a real-world patient cohort Bar, J.; Cai, M. H.; Choi, Y. C.; Baijal, S.; Zhao, W.; Liede, A.; Raskin, L.; Vasilopoulos, A.; Li, M.; Roberts-Rapp, L.; Jiang, F.; Ratajczak, C.; Lu, S.; Ansell, P. J.; Camidge, D. R. 分享 收藏
Phase Ib study of cofetuzumab pelidotin, an anti-PTK7 antibody-drug conjugate, in patients with PTK7-expressing recurrent non-small cell lung cancer (rNSCLC) Cho, B. C.; Johnson, M. L.; Bar, J.; Schaefer, E.; Yoh, K.; Zer, A.; Moskovitz, M. T.; Lee, S-H.; Moreno Garcia, V.; De Miguel Luken, M. J.; Okuma, Y.; Kim, J-H.; Lee, C-H.; Ansell, P. J.; de Almeida, C. Biesdorf; Saab, R.; Freise, K.; Ramies, D.; Jeng, E.; Camidge, D. R. 分享 收藏
Preliminary efficacy of telisotuzumab vedotin (Teliso-V) treatment in the 2L/3L setting in MET gene amplified ( MET Amp), c-Met protein overexpressing (c-Met OE), nonsquamous, non-small cell lung cancer (NSQ NSCLC): Retrospective analysis of LUMINOSITY Camidge, D. Ross; Goldman, Jonathan; Vasilopoulos, Athan; Ansell, Peter; Xia, Summer; Bolotin, Ellen; Looman, Jim; Ratajczak, Christine; Noon, Elysa; Lu, Shun 分享 收藏
c-MET mutations sensitize to antibody-drug conjugate telisotuzumab vedotin through efficient internalization and rapid intracellular drug delivery Batth, Izhar S.; Jaiswal, Bijay S.; Maji, Dolonchampa; Sparks, Robert; Glauser, William; Uziel, Tamar; Camidge, D. Ross; Vasilopoulos, Athan; Ansell, Peter; Epling-Burnette, P. K. 分享 收藏
Multi-omic characterization and predictive features of advanced ovarian cancer patients in a large phase III cohort Ramathal, Cyril; Masica, David; Ansell, Peter; Riley-Gillis, Bridget; Degner, Jacob; Bui, Thanh; Narayanan, Priya; Samayoa, Josue; Huang, Xin; Coleman, Robert F.; Waring, Jeffrey F. 分享 收藏
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma 抗表皮生长因子受体抗体药物偶联物serclutamab talirine的I期研究: 晚期胶质母细胞瘤的安全性，药代动力学和抗肿瘤活性 Carneiro, Benedito A.; Papadopoulos, Kyriakos P.; Strickler, John H.; Lassman, Andrew B.; Waqar, Saiama N.; Chae, Young Kwang; Patel, Jyoti D.; Shacham-Shmueli, Einat; Kelly, Karen; Khasraw, Mustafa; Bestvina, Christine M.; Merrell, Ryan; Huang, Kevin; Atluri, Harisha; Ansell, Peter; Li, Rachel; Jin, Janet; Anderson, Mark G.; Reilly, Edward B.; Morrison-Thiele, Gladys; Patel, Kalpesh; Robinson, Randy R.; Aristide, Martha R. Neagu; Gan, Hui K. 分享 收藏
First-in-human phase I study of ABBV-637 as monotherapy and in combination in patients with relapsed and refractory solid tumors Rotow, J.; Yoh, K.; Powderly, J. D.; Shimizu, T.; Perets, R.; Paz-Ares, L.; Phillips, A.; Souers, A.; Ansell, P. J.; Jin, J.; Badawi, M.; Saab, R.; Morrison-Thiele, G.; Jeffries, S.; Aristide, M. R. Neagu; Carneiro, B. A.; Papadopoulos, K. P. 分享 收藏
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: a phase III randomized clinical trial Depatuxizumab mafodotin治疗EGFR扩增的新诊断胶质母细胞瘤: 一项III期随机临床试验 Lassman, Andrew B.; Pugh, Stephanie L.; Wang, Tony J. C.; Aldape, Kenneth; Gan, Hui K.; Preusser, Matthias; Vogelbaum, Michael A.; Sulman, Erik P.; Won, Minhee; Zhang, Peixin; Moazami, Golnaz; Macsai, Marian S.; Gilbert, Mark R.; Bain, Earle E.; Blot, Vincent; Ansell, Peter J.; Samanta, Suvajit; Kundu, Madan G.; Armstrong, Terri S.; Wefel, Jeffrey S.; Seidel, Clemens; de Vos, Filip Y.; Hsu, Sigmund; Cardona, Andres F.; Lombardi, Giuseppe; Bentsion, Dmitry; Peterson, Richard A.; Gedye, Craig; Bourg, Veronique; Wick, Antje; Curran, Walter J.; Mehta, Minesh P. 分享 收藏
Veliparib Plus Carboplatin and Paclitaxel Versus Investigator's Choice of Standard Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer Govindan, Ramaswamy; Lind, Mike; Insa, Amelia; Khan, Saad A.; Uskov, Dmitry; Tafreshi, Ali; Guclu, Salih; Bar, Jair; Kato, Terufumi; Lee, Ki Hyeong; Nakagawa, Kazuhiko; Hansen, Olfred; Biesma, Bonne; Kundu, Madan G.; Dunbar, Martin; He, Lei; Ansell, Peter; Sehgal, Vasudha; Huang, Xin; Glasgow, Jaimee; Bach, Bruce A. 分享 收藏
Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer Zhang, Bingnan; Stewart, C. Allison; Wang, Qi; Cardnell, Robert J.; Rocha, Pedro; Fujimoto, Junya; Soto, Luisa M. Solis; Wang, Runsheng; Novegil, Veronica; Ansell, Peter; He, Lei; Fernandez, Luisa; Jendrisak, Adam; Gilbertson, Cole; Schonhoft, Joseph D.; Byun, Jiyun; Jones, Joshua; Anderson, Amanda K. L.; Aparicio, Ana; Tran, Hai; Negrao, Marcelo, V; Zhang, Jianjun; Wang, Wei-lien; Wistuba, Ignacio I.; Wang, Jing; Wenstrup, Rick; Byers, Lauren A.; Gay, Carl M. 分享 收藏
Matched cohort study of germline BRCA mutation carriers with triple negative breast cancer in brightness Metzger-Filho, Otto; Collier, Katharine; Asad, Sarah; Ansell, Peter J.; Watson, Mark; Bae, Junu; Cherian, Mathew; O'Shaughnessy, Joyce; Untch, Michael; Rugo, Hope S.; Huober, Jens B.; Golshan, Mehra; Sikov, William M.; von Minckwitz, Gunter; Rastogi, Priya; Li, Lang; Cheng, Lijun; Maag, David; Wolmark, Norman; Denkert, Carsten; Symmans, W. Fraser; Geyer, Charles E., Jr.; Loibl, Sibylle; Stover, Daniel G. 分享 收藏
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Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR Vaidya, Kedar S.; Mitten, Michael J.; Zelaya-Lazo, Adelyn L.; Oleksijew, Anatol; Alvey, Cory; Falls, Hugh D.; Mishra, Sasmita; Palma, Joann; Ansell, Peter; Phillips, Andrew C.; Reilly, Edward B.; Anderson, Mark; Boghaert, Erwin R. 分享 收藏
A Phase 1 and Biodistribution Study of ABT-806i, an 111In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806 Gan, Hui K.; Burge, Matthew; Solomon, Benjamin; Lee, Sze Ting; Holen, Kyle D.; Zhang, Yumin; Ciprotti, Marika; Lee, F. T.; Munasinghe, Wijith; Fischer, JuDee; Ansell, Peter; Fox, Gerard; Xiong, Hao; Reilly, Edward B.; Humerickhouse, Rod; Scott, Andrew M. 分享 收藏
A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors Lemech, Charlotte; Woodward, Natasha; Chan, Nancy; Mortimer, Joanne; Naumovski, Louie; Nuthalapati, Silpa; Tong, Bo; Jiang, Fang; Ansell, Peter; Ratajczak, Christine K.; Sachdev, Jasgit 分享 收藏
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