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T

Tuan Zea Tan

National University of Singapore
H指数:53
被引数:9,609

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Driver genomic lesions in MDM2, CDK4, and JUN co-opt targetable super-enhancer networks to impose liposarcomagenic core regulatory circuitry

MDM2、CDK4和JUN驱动基因突变利用可靶向的超级增强子网络构建脂肪肉瘤生成核心调控回路

Journal of Advanced Research
IF13
2026-08-310
OAAI
Ye Chen; Ying Zhang; Long Xie; Xiaorui Fan; Jiyang Liu; Tuan Zea Tan; Zhengming Yang; Pushkar Dakle; Suya Zheng; Nan Li; Chenying Wang; Victor Kwanmin Lee; Lingwen Ding; Qiaoyang Sun; Wen Yi; H. Phillip Koeffler; Liang Xu
Spatial transcriptomic profiling of ovarian clear cell carcinoma reveals heterogeneity in OXPHOS and EMT gradients

卵巢透明细胞癌的空间转录组学分析揭示了OXPHOS和EMT梯度中的异质性

Nature Communications
IF15.7
2026-07-080
OAAI
Thang Truong Le; Duncan Yi-Te Wang; Sebastian Rui-Gu Yan; Yi-Cian Chen; Ko-Chen Chen; Tuan Zea Tan; Pei-Yu Chu; Denis Ting-Hsian Chen; Yi-Chia Chiu; Jia-Yuh Sheu; Sydney Rechie Necesario; Chen-Hao Huang; Jieru Ye; Ya-Ting Tai; Hsueh-Fen Juan; Feng-Chiao Tsai; Wei-Chou Lin; Ying-Cheng Chiang; Lin-Hung Wei; Ruby Yun-Ju Huang
DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer

DP103作为Wnt信号通路和癌症干细胞的关键调控因子：对三阴性乳腺癌精准治疗的启示

Cell Death & Disease
IF9.6
2026-06-050
OAAI
Wanpei Cai; Sebastian Öther-Gee Pohl; Xianning Lai; Hiu Yan Lam; Catharine Shi-Yun Low; Vivien Koh; Haoran Ma; Mark Agostino; Arindam Banerjee; Nawat Bunnag; Jahnavi Suresh; Amudha Deivasigamani; Yi Yuan; Tuan Zea Tan; Muthukumar Rajasekaran; Jianxiang Chen; Hannah Lee Foon Swa; San Hue Hua; Shiyuan Guo; Janet Cheng-Fei Teng; Jas Min Chin; Jocelyn Yeen Hui Choy; Aye Aye Thike; Young Bok Lee; Madhu Mathi Kanchi; Karthik Ramesh; Yu Keung Mok; Ruby Yun-Ju Huang; Jayantha Gunaratne; Melissa Jane Fullwood; Puay Hoon Tan; George W. Yip; Gautam Sethi; Jeremy P. Blaydes; Celestial T. Yap; Peter Edward Lobie; Venetia Jing-Tong Kok; Arunasalam Dharmarajan; Kam Man Hui; Deog Joong Kim; Jit Kong Cheong; Nicholas Tolwinski; Wei Peng Yong; Patrick Tan; Kevin B. Myant; Alan Prem Kumar
Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers

线粒体中MDM2和TFAM的转位在治疗难治性癌症中重编程代谢

npj Precision Oncology
IF8
2026-04-160
OAAI
Jie Qing Eu; Nur Afiqah Binte Mohamed Salleh; Jayshree Hirpara; Naoto Ohi; Emiri Omori Takaki; Tuan Zea Tan; Ju Ee Seet; Susan Swee-Shan Hue; Shu Jun Chan; Dorothy Xi Yue Lim; Lingzhi Wang; Regina Tong Xin Wong; Azhar Ali; Yaw Chyn Lim; Boon-Cher Goh; Li Ren Kong; Shazib Pervaiz; Andrea LA Wong
Accelerated ageing predicts earlier onset of ischaemic stroke: a proteomic and transcriptomic investigation

加速老化预测缺血性卒中的更早发病：一项蛋白质组学和转录组学研究

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
IF7.5
2025-11-010
PRE
Quek, Amy May Lin; Teng, Ooiean; Tan, Tuan Zea; Park, Ju Hea; Er, Bernadette Guek Cheng; Goh, Jen-Yin; Jing, Mingxue; Tan, Benjamin Yong Qiang; Yeo, Leonard Y.; Chan, Bernard Poon Lap; Teoh, Hock Luen; Oh, Vernon Min Sen; Lim, Erle Chuen Hian; Seet, Raymond Chee Seong
A phase 1b, multicentre, dose escalation, safety and pharmacokinetics study of tilvestamab (BGB149) in relapsed, platinum-resistant, high-grade serous ovarian cancer (PROC) patients

一项关于tilvestamab（BGB149）在复发、铂耐药、高级别浆液性卵巢癌（PROC）患者中的1b期、多中心、剂量递增、安全性和药代动力学研究

British Journal of Cancer
IF6.8
2025-07-220
OAAI
Kenneth Sooi; Tuan Zea Tan; Jae-Weon Kim; Jung Yun Lee; Byoung-Gie Kim; David Micklem; Akil Jackson; David J. Pinato; Charlie Gourley; Rebecca Kristeleit; Sarah P. Blagden; Line Bjorge; David Shao Peng Tan
A multi-task domain-adapted model to predict chemotherapy response from mutations in recurrently altered cancer genes

一个多任务领域自适应模型，用于预测从复发性改变的癌基因突变中化疗反应

ISCIENCE
IF4.1
2025-02-010
OAAI
Jayagopal, Aishwarya; Walsh, Robert J.; Hariprasannan, Krishna Kumar; Mariappan, Ragunathan; Mahapatra, Debabrata; Jaynes, Patrick William; Lim, Diana; Tan, David Shao Peng; Tan, Tuan Zea; Pitt, Jason J.; Jeyasekharan, Anand D.; Rajan, Vaibhav
Comprehensive characterization of genomic features and clinical outcomes following targeted therapy and secondary cytoreductive surgery in OCCC: a single center experience
JOURNAL OF GYNECOLOGIC ONCOLOGY
IF3.7
2024-01-012
OAAI
Wijaya, Silvana Talisa; Ngoi, Natalie Y. L.; Loh, Jerold W. Z.; Tan, Tuan Zea; Lim, Diana; Khan, Irfan Sagir; Thian, Yee Liang; Lai, Alexa; Ang, Bertrand W. L.; Tong, Pearl; Ng, Joseph; Low, Jeffrey J. H.; Ilancheran, Arunachalam; Lim, Siew Eng; Lim, Yi Wan; Tan, David S. P.

研究方向

暂未获取到该数据
J
Jean Paul Thiery
H 指数:123论文数:962被引数:7.5万
R
Ruby Yun‐Ju Huang
H 指数:45论文数:193被引数:2.3万
D
David S.P. Tan
H 指数:50论文数:399被引数:1.0万
A
Alan Prem Kumar
H 指数:94论文数:370被引数:2.6万
J
Jieru Ye
H 指数:18论文数:67被引数:1,419
W
Wee Joo Chng
H 指数:85论文数:979被引数:3.5万
B
Boon Cher Goh
H 指数:65论文数:467被引数:1.7万
S
Seiichi Mori
H 指数:54论文数:357被引数:1.2万
V
Vin Yee Chung
H 指数:10论文数:28被引数:1,115
J
Jianbiao Zhou
H 指数:37论文数:150被引数:4,510