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Anand D. Jeyasekharan

National University of Singapore
H指数:34
被引数:5,404

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Single-cell pharmacogenomic landscapes of epigenetic therapy revealed by gastric cancer Perturb-seq

通过胃癌Perturb-seq揭示的表观遗传疗法的单细胞药物基因组景观

Nature Communications
IF15.7
2026-11-020
OAAI
Chang Xu; Haoran Ma; Taotao Sheng; Ming Hui Lee; Siti Aishah Binte Abdul Ghani; Shen Kiat Lim; Laura Perlaza-Jimenez; Kie Kyon Huang; Supriya Srivastava; Xuewen Ong; Su Ting Tay; Shamaine Wei Ting Ho; Zhi Xuan Ong; Angie Lay Keng Tan; Feng Zhu; Hassan Ashktorab; Alfred Sze-Lok Cheng; Anand D. Jeyasekharan; Shang Li; Ming Teh; Raghav Sundar; David R. Powell; Joseph Rosenbluh; Wei Peng Yong; Jimmy Bok-Yan So; Patrick Tan
Multimodal spatial profiling reveals distinct myeloid-defined ENKTL subgroups and tumor-myeloid cooperativity within prognostic inflammatory niche

多模态空间分析揭示髓系定义的ENKTL亚组及其在预后炎性微环境中的肿瘤-髓系协同作用

Leukemia
IF13.4
2026-08-240
OAAI
Lichang Deng; Min Liu; Reagan Entigu Anak Linton; Kaijie Hu; Shruti Sridhar; Giorgio Bertolazzi; Sai Mun Leong; Ling-Wen Ding; Nicholas Syn; Shuangyi Fan; Cho Mar Myint Wai; Yi-Qi Li; Jin-Xin Bei; Jie Xiong; Wei-Li Zhao; Susan Swee-Shan Hue; Joe Poh Sheng Yeong; Li Yen Chong; Li-Mei Poon; Choon Kiat Ong; Jing Quan Lim; Soon Thye Lim; Jinmiao Chen; Hang Xu; Anand Devaprasath Jeyasekharan; Claudio Tripodo; Siok-Bian Ng
A synergistic interaction between PRMT5 and LSD1 inhibitors in AML

PRMT5与LSD1抑制剂的协同作用在AML中

Science Advances
IF12.5
2026-03-270
OA
Nesteene Joy Param; Elisa Arceci; Francesco Fiorentino; Luca Pignata; Denis Torre; Nayeli Gutiérrez-Trejo; Jia Yi Fong; Pierre-Alexis Goy; Brenda Y. Han; Chiara Lambona; Elisabetta Di Bello; Carola Castiello; Marco Barone; Megan Schwarz; Cheryl Arrowsmith; Koichi Ito; Peggy Scherle; Dave Keng Boon Wee; Steven Ndoye; Tommaso Tabaglio; Anand D. Jeyasekharan; Manikandan Lakshmanan; Roberto Cirilli; Hansjörg Habisch; Tobias Madl; Andrea Mattevi; Sergio Valente; Antonello Mai; Ernesto Guccione
Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone

弥漫大B细胞淋巴瘤保留ATR依赖性的生发中心暗区T细胞排斥决定因素

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-09-160
OA
Cancila, Valeria; Bertolazzi, Giorgio; Chan, Allison S. Y.; Medico, Giovanni; Bastianello, Giulia; Morello, Gaia; Paysan, Daniel; Lai, Clemence; Hong, Liang; Shenoy, Girija; Jaynes, Patrick W.; Schiavoni, Giovanna; Mattei, Fabrizio; Piconese, Silvia; Revuelta, Maria V.; Noto, Francesco; Businaro, Luca; Ninno, Adele De; Cammarata, Ilenia; Pagni, Fabio; Venkatachalapathy, Saradha; Sangaletti, Sabina; Di Napoli, Arianna; Cicio, Giada; Vacca, Davide; Lonardi, Silvia; Lorenzi, Luisa; Ferreri, Andres J. M.; Belmonte, Beatrice; Liu, Min; Lakshmanan, Manikandan; Ong, Michelle S. N.; Zhang, Biyan; See, Tingyi; Lam, Kong-Peng; Varano, Gabriele; Colombo, Mario P.; Bicciato, Silvio; Inghirami, Giorgio; Cerchietti, Leandro; Ponzoni, Maurilio; Zappasodi, Roberta; Metzger, Evelyn; Beechem, Joseph; Facchetti, Fabio; Foiani, Marco; Casola, Stefano; Jeyasekharan, Anand D.; Tripodo, Claudio
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma

全基因组活体内CRISPR筛选鉴定GATOR1复合物为Myc驱动的淋巴瘤的肿瘤抑制因子

Nature Communications
IF15.7
2025-08-210
OAAI
Margaret A. Potts; Shinsuke Mizutani; Yexuan Deng; Srimayee Vaidyanathan; Keziah E. Ting; Göknur Giner; Shruti Sridhar; Girija Shenoy; Yang Liao; Sarah T. Diepstraten; Andrew J. Kueh; Martin Pal; Geraldine Healey; Lin Tai; Zilu Wang; Christina König; Deeksha Kaloni; Lauren Whelan; Michael J. G. Milevskiy; Hannah D. Coughlan; Giovanna Pomilio; Andrew H. Wei; Jane E. Visvader; Anthony T. Papenfuss; Stephen Wilcox; Anand D. Jeyasekharan; Wei Shi; Emily J. Lelliott; Gemma L. Kelly; Kristin K. Brown; Andreas Strasser; Marco J. Herold
The transcription complex p52–ETS1 is essential for germinal center formation

转录复合物p52–ETS1对于生发中心的形成至关重要。

Nature Immunology
IF27.6
2025-07-250
PRE
Dhakshayini Morgan; Biyan Zhang; Kerem Fidan; Wenfai Pan; Thamil Selvan Vaiyapuri; Anandhkumar Raju; Dorcas Hei; Ting Yi See; Ita Novita Sari; Jun Wei Chan; Prativa Majee; Akhila Balachander; Jiabo Yu; Ada Hang-Heng Wong; Michelle Meng Huang Mok; Shi Hui Foo; Wei Lin Tang; Nicholas Ang; Ivan Tan; Yan Fen Peng; Patrick Jaynes; Shengli Xu; Gourisankar Ghosh; Shandy Shahabi; Anand D. Jeyasekharan; Masahito Ikawa; Yongliang Zhang; Shanshan Wu Howland; Mai Chan Lau; Vivien Ya-Fan Wang; Kong-Peng Lam; Vinay Tergaonkar
A multi-task domain-adapted model to predict chemotherapy response from mutations in recurrently altered cancer genes

一个多任务领域自适应模型，用于预测从复发性改变的癌基因突变中化疗反应

ISCIENCE
IF4.1
2025-02-010
OAAI
Jayagopal, Aishwarya; Walsh, Robert J.; Hariprasannan, Krishna Kumar; Mariappan, Ragunathan; Mahapatra, Debabrata; Jaynes, Patrick William; Lim, Diana; Tan, David Shao Peng; Tan, Tuan Zea; Pitt, Jason J.; Jeyasekharan, Anand D.; Rajan, Vaibhav
Machine Learning Classification of Spatial Patterns of Malignant Cells Reveals Implications in Prognosis and Tumor Microenvironment Composition in Lymphoma

机器学习对恶性细胞空间模式的分类揭示了其在淋巴瘤预后和肿瘤微环境组成方面的意义

BLOOD
IF23.1
2024-11-050
PRE
Sridhar, Shruti; Hoppe, Michal Marek; Jaynes, Patrick; Kumar, Gayatri; Jasoria, Siddham; Meng, Ziwei; Peng, Yanfen; De Mel, Sanjay; Poon, Limei; Chan, Esther Hian Li; Chng, Wee-Joo; Tan, Soo Yong; Hue, Susan Swee-Shan; Ng, Siok-Bian; Nagarajan, Chandramouli; Grigoropoulos, Nicholas Francis; Li, Shaoying; Khoury, Joseph D.; Farinha, Pedro; Mottok, Anja; Scott, David W.; Ye, Xiaofei; Pan-Hammarstroem, Qiang; Rajan, Vaibhav; Kannan, Kasthuri; Jeyasekharan, Anand Devaprasath D.
Single Cell Resolution Spatial Modeling Uncovers Survival-associated Phenotypes in Diffuse Large B Cell Lymphoma
CANCER RESEARCH
IF16.6
2024-04-150
PRE
Sridhar, Shruti; Hoppe, Michal Marek; Liu, Min; Jaynes, Patrick; Peng, Yanfen; De Mel, Sanjay; Poon, Limei; Chan, Esther Hian Li; Lee, Joanne; Nagarajan, Chandramouli; Grigoropoulos, Nicholas F.; Tan, Soo-Yong; Hue, Susan Swee-Shan; Li, Shaoying; Khoury, Joseph D.; Farinha, Pedro; Mottok, Anja; Scott, David W.; Kumar, Gayatri; Kannan, Kasthuri; Chng, Wee Joo; Chee, Yen Lin; Ng, Siok-Bian; Tripodo, Claudio; Jeyasekharan, Anand D.

研究方向

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M
Michał Marek Hoppe
H 指数:11论文数:73被引数:798
P
Patrick Jaynes
H 指数:12论文数:95被引数:598
W
Wee Joo Chng
H 指数:85论文数:979被引数:3.6万
S
Siok‐Bian Ng
H 指数:40论文数:230被引数:9,864
C
Choon Kiat Ong
H 指数:62论文数:435被引数:2.5万
S
Sanjay De Mel
H 指数:23论文数:210被引数:1,699
S
Soon Thye Lim
H 指数:46论文数:381被引数:8,182
D
David S.P. Tan
H 指数:50论文数:399被引数:1.0万
R
Raghav Sundar
H 指数:42论文数:382被引数:6,491
S
Soo‐Yong Tan
H 指数:38论文数:233被引数:5,852