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D

Daniel Ajona

cancer center clinica universidad de navarra
H指数:31
被引数:4,340

个人简介

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教育背景

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工作经历

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荣誉奖项

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Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer

双重ENPP1/ATM耗竭可使DNA损伤修复增强放射免疫功效以消除三阴性乳腺癌

Signal Transduction and Targeted Therapy
IF52.7
2025-06-130
OAAI
Borja Ruiz-Fernández de Córdoba; Karmele Valencia; Connor Welch; Haritz Moreno; Susana Martínez-Canarias; Carolina Zandueta; Eduardo Gómez; Alfonso Calvo; Nerea Otegui; Mirari Echepare; Ignacio Garzón; Daniel Ajona; David Lara-Astiaso; Elisabeth Guruceaga; Laura Guembe; Rubén Pío; Ignacio Melero; Silve Vicent; Fernando Pastor; Rafael Martínez-Monge; Fernando Lecanda
Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation

曲美替尼通过Id1下调使KRAS突变型肺腺癌肿瘤对PD-1/PD-L1轴阻滞敏感

MOLECULAR CANCER
IF33.9
2024-04-201
OAAI
Puyalto, Ander; Rodriguez-Remirez, Maria; Lopez, Ines; Macaya, Irati; Guruceaga, Elizabeth; Olmedo, Maria; Vilalta-Lacarra, Anna; Welch, Connor; Sandiego, Sergio; Vicent, Silvestre; Valencia, Karmele; Calvo, Alfonso; Pio, Ruben; Raez, Luis E.; Rolfo, Christian; Ajona, Daniel; Gil-Bazo, Ignacio
Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer
EMBO REPORTS
IF6.2
2023-06-276
OA
Bocanegra, Ana; Fernandez-Hinojal, Gonzalo; Ajona, Daniel; Blanco, Ester; Zuazo, Miren; Garnica, Maider; Chocarro, Luisa; Alfaro-Arnedo, Elvira; Pineiro-Hermida, Sergio; Morente, Pilar; Fernandez, Leticia; Remirez, Ana; Echaide, Miriam; Martinez-Aguillo, Maite; Morilla, Idoia; Tavira, Beatriz; Roncero, Alejandra; Gotera, Carolina; Ventura, Alfonso; Recalde, Nerea; Pichel, Jose G.; Lasarte, Juan Jose; Montuenga, Luis; Vera, Ruth; Pio, Ruben; Escors, David; Kochan, Grazyna
Combined treatment with the epigenetic drug CM272 and an anti-BCL-XL proapoptotic drug sensitizes solid tumors to immune checkpoint blockade
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Senent, Yaiza; Fresquet, Vicente; Jimenez, Victoria; Valencia, Karmele; Remirez, Ana; Exposito, Francisco; Gonzalez-Huarriz, Marisol; de Cordoba, Borja Ruiz-Fernandez; Moreno, Haritz; Ajona, Daniel; Alonso, Marta M.; Lecanda, Fernando; Pineda-Lucena, Antonio; Prosper, Felipe; Calvo, Alfonso; Martinez-Climent, Jose Angel; Pio, Ruben
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
CANCER LETTERS
IF10.1
2022-03-0161
PRE
Ortiz-Espinosa, Sergio; Morales, Xabier; Senent, Yaiza; Alignani, Diego; Tavira, Beatriz; Macaya, Irati; Ruiz, Borja; Moreno, Haritz; Remirez, Ana; Sainz, Cristina; Rodriguez-Pena, Alejandro; Oyarbide, Alvaro; Ariz, Mikel; Andueza, Maria P.; Valencia, Karmele; Teijeira, Alvaro; Hoehlig, Kai; Vater, Axel; Rolfe, Barbara; Woodruff, Trent M.; Maria Lopez-Picazo, Jose; Vicent, Silvestre; Kochan, Grazyna; Escors, David; Gil-Bazo, Ignacio; Luis Perez-Gracia, Jose; Montuenga, Luis M.; Lambris, John D.; Ortiz de Solorzano, Carlos; Lecanda, Fernando; Ajona, Daniel; Pio, Ruben
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
CANCER DISCOVERY
IF33.3
2022-02-2131
OAAI
Ruiz-Fernandez de Cordoba, Borja; Moreno, Haritz; Valencia, Karmele; Perurena, Naiara; Ruedas, Pablo; Walle, Thomas; Pezonaga-Torres, Alberto; Hinojosa, Juan; Guruceaga, Elisabet; Pineda-Lucena, Antonio; Abengozar-Muela, Marta; Cochonneau, Denis; Zandueta, Carolina; Martinez-Canarias, Susana; Teijeira, Alvaro; Ajona, Daniel; Ortiz-Espinosa, Sergio; Morales, Xabier; Ortiz de Solorzano, Carlos; Santisteban, Marta; Ramos-Garcia, Luis, I; Guembe, Laura; Strnad, Vratislav; Heymann, Dominique; Hervas-Stubbs, Sandra; Pio, Ruben; Rodriguez-Ruiz, Maria E.; de Andrea, Carlos E.; Vicent, Silvestre; Melero, Ignacio; Lecanda, Fernando; Martinez-Monge, Rafael
Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma
DISEASE MODELS & MECHANISMS
IF3.3
2022-01-317
OAAI
Valencia, Karmele; Sainz, Cristina; Bertolo, Cristina; de Biurrun, Gabriel; Agorreta, Jackeline; Azpilikueta, Arantza; Larrayoz, Marta; Bosco, Graziella; Zandueta, Carolina; Redrado, Miriam; Redin, Esther; Exposito, Francisco; Serrano, Diego; Echepare, Mirari; Ajona, Daniel; Melero, Ignacio; Pio, Ruben; Thomas, Roman; Calvo, Alfonso; Montuenga, Luis M.
A model based on the quantification of complement C4c, CYFRA 21-1 and CRP exhibits high specificity for the early diagnosis of lung cancer
TRANSLATIONAL RESEARCH
IF5.9
2021-07-0117
OAAI
AJONA, D. A. N. I. E. L.; REMIREZ, A. N. A.; SAINZ, C. R. I. S. T. I. N. A.; BERTOLO, C. R. I. S. T. I. N. A.; GONZALEZ, A. L. V. A. R. O.; VARO, N. E. R. E. A.; LOZANO, M. A. R. I. A. D.; ZULUETA, J. A. V. I. E. R. J.; MESA-GUZMAN, M. I. G. U. E. L.; MARTIN, A. N. A. C.; PEREZ-PALACIOS, R. O. S. A.; PEREZ-GRACIA, J. O. S. E. L. U. I. S.; MASSION, P. I. E. R. R. E. P.; MONTUENGA, L. U. I. S. M.; PIO, R. U. B. E. N.

研究方向

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R
Rubén Pı́o
H 指数:52论文数:299被引数:8,436
L
Luis M. Montuenga
H 指数:61论文数:534被引数:1.4万
A
Alfonso Calvo
H 指数:49论文数:436被引数:7,264
M
María J. Pajares
H 指数:36论文数:149被引数:4,332
F
Fernando Lecanda
H 指数:45论文数:257被引数:6,689
K
Karmele Valencia
H 指数:21论文数:173被引数:1,749
J
Jackeline Agorreta
H 指数:30论文数:118被引数:3,560
S
Sergio Ortiz‐Espinosa
H 指数:11论文数:31被引数:1,194
C
Cristina Bértolo
H 指数:15论文数:29被引数:1,087
H
Haritz Moreno
H 指数:11论文数:59被引数:1,206