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F

Fernando Lecanda

Center for Applied Medical Research and University of Navarra
H指数:45
被引数:6,673

个人简介

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教育背景

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工作经历

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荣誉奖项

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Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer

双重ENPP1/ATM耗竭可使DNA损伤修复增强放射免疫功效以消除三阴性乳腺癌

Signal Transduction and Targeted Therapy
IF52.7
2025-06-130
OAAI
Borja Ruiz-Fernández de Córdoba; Karmele Valencia; Connor Welch; Haritz Moreno; Susana Martínez-Canarias; Carolina Zandueta; Eduardo Gómez; Alfonso Calvo; Nerea Otegui; Mirari Echepare; Ignacio Garzón; Daniel Ajona; David Lara-Astiaso; Elisabeth Guruceaga; Laura Guembe; Rubén Pío; Ignacio Melero; Silve Vicent; Fernando Pastor; Rafael Martínez-Monge; Fernando Lecanda
DSTYK Inhibition Sensitizes NSCLC to Taxane-Based Chemotherapy

DSTYK抑制增强了非小细胞肺癌对紫杉烷类化疗的敏感性

JOURNAL OF THORACIC ONCOLOGY
IF20.8
2024-11-010
PRE
Echepare, Mirari; Picabea, Benat; Arricibita, Andrea; Teijeira, Alvaro; Pasquier, Andrea; Zandueta, Carolina; Otegui, Nerea; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Romero, Octavio; Sanchez-Cespedes, Montse; Lecanda, Fernando; Hernandez, Javier; Felip, Enriqueta; Provencio, Mariano; Facchinetti, Federica; Roz, Luca; Montuenga, Luis M.; Valencia, Karmele
Underlying germline genetic architecture of pediatric sarcomas: Evaluating the role of common and rare variants in 4,160 patients
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Mirabello, Lisa; Egolf, Laura E.; Zhu, Bin; Gianferante, D. Matthew; Wang, Kevin; Li, Shengchao Alfred; Machiela, Mitchell J.; Spector, Logan G.; Schiffman, Joshua D.; Sabo, Aniko; Renwick, Alexander; Martin-Giacalone, Bailey; Scheurer, Michael E.; Plon, Sharon; Hawkins, Douglas; Venkatramani, Rajkumar; Stewart, Douglas; Morton, Lindsay M.; Hudson, Melissa M.; Armstrong, Gregory T.; Bhatia, Smita; Dean, Michael; Janeway, Katherine A.; Patino-Garcia, Ana; Lecanda, Fernando; Serra, Massimo; Hattinger, Claudia; Scotlandi, Katia; Flanagan, Adrienne M.; Amary, Fernanda; Andrulis, Irene L.; Wunder, Jay S.; Ballinger, Mandy L.; Thomas, David M.; Delattre, Olivier; Hubbard, Aubrey K.; Liu, Jia; Luo, Wen; Hicks, Belynda D.; Yeager, Meredith; Rafati, Maryam; Huang, Wen-Yi; Landi, Maria T.; Lori, Adriana; Diver, Ryan; Savage, Sharon A.; Chanock, Stephen J.; Lupo, Philip J.
Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer
NATURE COMMUNICATIONS
IF15.7
2023-10-109
OAAI
Macaya, Irati; Roman, Marta; Welch, Connor; Entrialgo-Cadierno, Rodrigo; Salmon, Marina; Santos, Alba; Feliu, Iker; Kovalski, Joanna; Lopez, Ines; Rodriguez-Remirez, Maria; Palomino-Echeverria, Sara; Lonfgren, Shane M.; Ferrero, Macarena; Calabuig, Silvia; Ludwig, Iziar A.; Lara-Astiaso, David; Jantus-Lewintre, Eloisa; Guruceaga, Elizabeth; Narayanan, Shruthi; Ponz-Sarvise, Mariano; Pineda-Lucena, Antonio; Lecanda, Fernando; Ruggero, Davide; Khatri, Purvesh; Santamaria, Enrique; Fernandez-Irigoyen, Joaquin; Ferrer, Irene; Paz-Ares, Luis; Drosten, Matthias; Barbacid, Mariano; Gil-Bazo, Ignacio; Vicent, Silve
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer (vol 22, 86, 2023)
MOLECULAR CANCER
IF33.9
2023-06-162
OAAI
Entrialgo-Cadierno, Rodrigo; Cueto-Urena, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goni-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer

磷脂转运蛋白PITPNC1将KRAS与MYC连接以防止肺癌和胰腺癌中的自噬

MOLECULAR CANCER
IF33.9
2023-05-209
OAAI
Entrialgo-Cadierno, Rodrigo; Cueto-Urena, Cristina; Welch, Connor; Feliu, Iker; Macaya, Irati; Vera, Laura; Morales, Xabier; Michelina, Sandra Vietti; Scaparone, Pietro; Lopez, Ines; Darbo, Elodie; Erice, Oihane; Vallejo, Adrian; Moreno, Haritz; Goni-Salaverri, Ainhoa; Lara-Astiaso, David; Halberg, Nils; Cortes-Dominguez, Ivan; Guruceaga, Elizabeth; Ambrogio, Chiara; Lecanda, Fernando; Vicent, Silve
Combined treatment with the epigenetic drug CM272 and an anti-BCL-XL proapoptotic drug sensitizes solid tumors to immune checkpoint blockade
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Senent, Yaiza; Fresquet, Vicente; Jimenez, Victoria; Valencia, Karmele; Remirez, Ana; Exposito, Francisco; Gonzalez-Huarriz, Marisol; de Cordoba, Borja Ruiz-Fernandez; Moreno, Haritz; Ajona, Daniel; Alonso, Marta M.; Lecanda, Fernando; Pineda-Lucena, Antonio; Prosper, Felipe; Calvo, Alfonso; Martinez-Climent, Jose Angel; Pio, Ruben
Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood

高效富集血液中循环肿瘤细胞的可调惯性微流控系统设计与验证

BIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
2022-04-297
OAAI
Rodriguez-Pena, Alejandro; Armendariz, Estibaliz; Oyarbide, Alvaro; Morales, Xabier; Ortiz-Espinosa, Sergio; Ruiz-Fernandez de Cordoba, Borja; Cochonneau, Denis; Cornago, Inaki; Heymann, Dominique; Argemi, Josepmaria; D'Avola, Delia; Sangro, Bruno; Lecanda, Fernando; Pio, Ruben; Cortes-Dominguez, Ivan; Ortiz-de-Solorzano, Carlos
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
CANCER LETTERS
IF10.1
2022-03-0161
PRE
Ortiz-Espinosa, Sergio; Morales, Xabier; Senent, Yaiza; Alignani, Diego; Tavira, Beatriz; Macaya, Irati; Ruiz, Borja; Moreno, Haritz; Remirez, Ana; Sainz, Cristina; Rodriguez-Pena, Alejandro; Oyarbide, Alvaro; Ariz, Mikel; Andueza, Maria P.; Valencia, Karmele; Teijeira, Alvaro; Hoehlig, Kai; Vater, Axel; Rolfe, Barbara; Woodruff, Trent M.; Maria Lopez-Picazo, Jose; Vicent, Silvestre; Kochan, Grazyna; Escors, David; Gil-Bazo, Ignacio; Luis Perez-Gracia, Jose; Montuenga, Luis M.; Lambris, John D.; Ortiz de Solorzano, Carlos; Lecanda, Fernando; Ajona, Daniel; Pio, Ruben
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
CANCER DISCOVERY
IF33.3
2022-02-2131
OAAI
Ruiz-Fernandez de Cordoba, Borja; Moreno, Haritz; Valencia, Karmele; Perurena, Naiara; Ruedas, Pablo; Walle, Thomas; Pezonaga-Torres, Alberto; Hinojosa, Juan; Guruceaga, Elisabet; Pineda-Lucena, Antonio; Abengozar-Muela, Marta; Cochonneau, Denis; Zandueta, Carolina; Martinez-Canarias, Susana; Teijeira, Alvaro; Ajona, Daniel; Ortiz-Espinosa, Sergio; Morales, Xabier; Ortiz de Solorzano, Carlos; Santisteban, Marta; Ramos-Garcia, Luis, I; Guembe, Laura; Strnad, Vratislav; Heymann, Dominique; Hervas-Stubbs, Sandra; Pio, Ruben; Rodriguez-Ruiz, Maria E.; de Andrea, Carlos E.; Vicent, Silvestre; Melero, Ignacio; Lecanda, Fernando; Martinez-Monge, Rafael
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted
JOURNAL OF HEPATOLOGY
IF33
2021-08-0134
OAAI
Vallejo, Adrian; Erice, Oihane; Entrialgo-Cadierno, Rodrigo; Feliu, Iker; Guruceaga, Elizabeth; Perugorria, Maria J.; Olaizola, Paula; Muggli, Alexandra; Macaya, Irati; O'Dell, Michael; Ruiz-Fernandez De Cordoba, Borja; Ortiz-Espinosa, Sergio; Hezel, Aram F.; Arozarena, Imanol; Lecanda, Fernando; Avila, Matias A.; Fernandez-Barrena, Maite G.; Evert, Matthias; Ponz-Sarvise, Mariano; Calvisi, Diego F.; Banales, Jesus M.; Vicent, Silve
Sarcoma treatment in the era of molecular medicine

分子医学时代的肉瘤治疗

EMBO MOLECULAR MEDICINE
IF8.3
2020-10-13173
OAAI
Grunewald, Thomas G. P.; Alonso, Marta; Avnet, Sofia; Banito, Ana; Burdach, Stefan; Cidre-Aranaz, Florencia; Di Pompo, Gemma; Distel, Martin; Dorado-Garcia, Heathcliff; Garcia-Castro, Javier; Gonzalez-Gonzalez, Laura; Grigoriadis, Agamemnon E.; Kasan, Merve; Koelsche, Christian; Krumbholz, Manuela; Lecanda, Fernando; Lemma, Silvia; Longo, Dario L.; Madrigal-Esquivel, Claudia; Morales-Molina, Alvaro; Musa, Julian; Ohmura, Shunya; Ory, Benjamin; Pereira-Silva, Miguel; Perut, Francesca; Rodriguez, Rene; Seeling, Carolin; Al Shaaili, Nada; Shaabani, Shabnam; Shiavone, Kristina; Sinha, Snehadri; Tomazou, Eleni M.; Trautmann, Marcel; Vela, Maria; Versleijen-Jonkers, Yvonne M. H.; Visgauss, Julia; Zalacain, Marta; Schober, Sebastian J.; Lissat, Andrej; English, William R.; Baldini, Nicola; Heymann, Dominique
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-03-0928
OAAI
Valencia, Karmele; Erice, Oihane; Kostyrko, Kaja; Hausmann, Simone; Guruceaga, Elizabeth; Tathireddy, Anuradha; Flores, Natasha M.; Sayles, Leanne C.; Lee, Alex G.; Fragoso, Rita; Sun, Tian-Qiang; Vallejo, Adrian; Roman, Marta; Entrialgo-Cadierno, Rodrigo; Migueliz, Itziar; Razquin, Nerea; Fortes, Puri; Lecanda, Fernando; Lu, Jun; Ponz-Sarvise, Mariano; Chen, Chang-Zheng; Mazur, Pawel K.; Sweet-Cordero, E. Alejandro; Vicent, Silvestre
Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade

短期饥饿降低IGF-1水平，使肺肿瘤对PD-1免疫检查点阻滞敏感

NATURE CANCER
IF28.5
2020-01-1393
PREAI
Ajona, Daniel; Ortiz-Espinosa, Sergio; Lozano, Teresa; Exposito, Francisco; Calvo, Alfonso; Valencia, Karmele; Redrado, Miriam; Remirez, Ana; Lecanda, Fernando; Alignani, Diego; Lasarte, Juan J.; Macaya, Irati; Senent, Yaiza; Bertolo, Cristina; Sainz, Cristina; Gil-Bazo, Ignacio; Eguren-Santamaria, Inaki; Lopez-Picazo, Jose M.; Gonzalez, Alvaro; Perez-Gracia, Jose L.; de Andrea, Carlos E.; Vicent, Silvestre; Sanmamed, Miguel F.; Montuenga, Luis M.; Pio, Ruben
YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2019-10-0154
OAAI
Garmendia, Irati; Pajares, Maria J.; Hermida-Prado, Francisco; Ajona, Daniel; Bertolo, Cristina; Sainz, Cristina; Lavin, Amaya; Remirez, Ana B.; Valencia, Karmele; Moreno, Haritz; Ferrer, Irene; Behrens, Carmen; Cuadrado, Myriam; Paz-Ares, Luis; Bustelo, Xose R.; Gil-Bazo, Ignacio; Alameda, Daniel; Lecanda, Fernando; Calvo, Alfonso; Felip, Enriqueta; Sanchez-Cespedes, Montse; Wistuba, Ignacio I.; Granda-Diaz, Rocio; Pablo Rodrigo, Juan; Maria Garcia-Pedrero, Juana; Pio, Ruben; Montuenga, Luis M.; Agorreta, Jackeline

研究方向

暂未获取到该数据
C
Carolina Zandueta
H 指数:19论文数:62被引数:1,292
A
Ana Patiño‐García
H 指数:46论文数:322被引数:7,099
K
Karmele Valencia
H 指数:21论文数:173被引数:1,738
S
Silvestre Vicent
H 指数:34论文数:187被引数:3,577
R
Rubén Pı́o
H 指数:52论文数:299被引数:8,418
I
Iker Antón
H 指数:10论文数:61被引数:704
D
Diego Luis-Ravelo
H 指数:15论文数:49被引数:3,338
S
Sharon A. Savage
H 指数:76论文数:575被引数:2.3万
D
Daniel Ajona
H 指数:31论文数:135被引数:4,326
M
Meredith Yeager
H 指数:91论文数:585被引数:3.3万