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Multi-Omic Analyses of TP53-Mutated Acute Myeloid Leukemia Identify Prognostic Metabolic Signatures 多组学分析识别TP53突变急性髓系白血病的预后代谢特征 Uadakekolathu, Jayakumar; Skuli, Sarah; Boocock, David J.; Coveney, Clare; Ikpo, Eruchi G.; Wang, Bofei; Fenu, Elena M.; Abbas, Hussein A.; Lai, Catherine E.; Carroll, Martin P.; Rutella, Sergio 分享 收藏
Safety and efficacy of autologous haematopoietic stem-cell transplantation with low-dose cyclophosphamide mobilisation and reduced intensity conditioning versus standard of care in refractory Crohn's disease (ASTIClite): an open-label, multicentre, randomised controlled trial 自体造血干细胞移植联合低剂量环磷酰胺动员和低强度预处理与标准治疗难治性克罗恩病的安全性和有效性 (ASTIClite): 一项开放标签、多中心、随机对照试验 Lindsay, James O.; Hind, Daniel; Swaby, Lizzie; Berntsson, Hannah; Bradburn, Mike; Bannur, C. Uday; Byrne, Jennifer; Clarke, Christopher; Desoysa, Lauren; Dickins, Ben; Din, Shahida; Emsley, Richard; Foulds, Gemma A.; Gribben, John; Hawkey, Christopher; Irving, Peter M.; Kazmi, Majid; Lee, Ellen; Loban, Amanda; Lobo, Alan; Mahida, Yashwant; Moran, Gordon W.; Papaioannou, Diana; Parkes, Miles; Peniket, Andrew; Pockley, A. Graham; Satsangi, Jack; Subramanian, Sreedhar; Travis, Simon; Turton, Emily; Uttenthal, Ben; Rutella, Sergio; Snowden, John A. 分享 收藏
WU-NK-101, best in class memory-NK cell, has key features vital for adoptive cell therapy (ACT) in solid tumors (ST) Muth, J.; Leedom, T.; Magee, K.; Muz, B.; Vadakekulathu, J.; Petit, V.; Bhatnagar, N.; Primo, D.; Pennacchi, P. Comune; Berrien-Elliott, M.; Fehniger, T. A.; Davidson-Moncada, J.; Rutella, S. 分享 收藏
xWU-NK-101 as salvage therapy post immune checkpoint blockade (ICB) Leedom, Tom A.; Muz, Barbara; Vadakekolathu, Jaykumar; Muth, John J.; Li, Xiao-Hua; Watson, Gregory; Magee, Kristaan; Sullivan, Ryan P.; Berrien-Elliott, Melissa; Fenigher, Todd; Rutella, Sergio; Cooper, Matthew L.; Kabakibi, Ayman; Davidson-Moncada, Jan K. 分享 收藏
Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia Rutella, Sergio; Vadakekolathu, Jayakumar; Mazziotta, Francesco; Reeder, Stephen; Yau, Tung -On; Mukhopadhyay, Rupkatha; Dickins, Benjamin; Altmann, Heidi; Kramer, Michael; Knaus, Hanna A.; Blazar, Bruce R.; Radojcic, Vedran; Zeidner, Joshua F.; Arruda, Andrea; Wang, Bofei; Abbas, Hussein A.; Minden, Mark D.; Tasian, Sarah K.; Bornhaeuser, Martin; Gojo, Ivana; Luznik, Leo 分享 收藏
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An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia Ragaini, Simone; Wagner, Sarah; Marconi, Giovanni; Parisi, Sarah; Sartor, Chiara; Nanni, Jacopo; Cristiano, Gianluca; Talami, Annalisa; Olivi, Matteo; Ocadlikova, Darina; Ciciarello, Marilena; Corradi, Giulia; Ottaviani, Emanuela; Papayannidis, Cristina; Paolini, Stefania; Vadakekolathu, Jayakumar; Cavo, Michele; Rutella, Sergio; Curti, Antonio 分享 收藏
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TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML Vadakekolathu, Jayakumar; Lai, Catherine; Reeder, Stephen; Church, Sarah E.; Hood, Tressa; Lourdusamy, Anbarasu; Rettig, Michael P.; Aldoss, Ibrahim; Advani, Anjali S.; Godwin, John; Wieduwilt, Matthew J.; Arellano, Martha; Muth, John; Yau, Tung On; Ravandi, Farhad; Sweet, Kendra; Altmann, Heidi; Foulds, Gemma A.; Stoelzel, Friedrich; Middeke, Jan Moritz; Ciciarello, Marilena; Curti, Antonio; Valk, Peter J. M.; Loewenberg, Bob; Gojo, Ivana; Bornhaeuser, Martin; DiPersio, John F.; Davidson-Moncada, Jan K.; Rutella, Sergio 分享 收藏
TP53 abnormalities correlate with immune infiltration and are associated with response to flotetuzumab, an investigational immunotherapy, in acute myeloid leukemia Vadakekolathu, Jayakumar; Lai, Catherine; Reeder, Stephen; Church, Sarah E.; Hood, Tressa; Muth, John; Altmann, Heidi; Ciciarello, Marilena; Curti, Antonio; Valk, Peter J.; Lowenberg, Bob; Bornhaeuser, Martin; DiPersio, John F.; Davidson-Moncada, Jan K.; Rutella, Sergio 分享 收藏
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia Vadakekolathu, Jayakumar; Minden, Mark D.; Hood, Tressa; Church, Sarah E.; Reeder, Stephen; Altmann, Heidi; Sullivan, Amy H.; Viboch, Elena J.; Patel, Tasleema; Ibrahimova, Narmin; Warren, Sarah E.; Arruda, Andrea; Liang, Yan; Smith, Thomas H.; Foulds, Gemma A.; Bailey, Michael D.; Gowen-MacDonald, James; Muth, John; Schmitz, Marc; Cesano, Alessandra; Pockley, A. Graham; Valk, Peter J. M.; Lowenberg, Bob; Bornhaeuser, Martin; Tasian, Sarah K.; Rettig, Michael P.; Davidson-Moncada, Jan K.; DiPersio, John F.; Rutella, Sergio 分享 收藏
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Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer Foulds, Gemma A.; Vadakekolathu, Jayakumar; Abdel-Fatah, Tarek M. A.; Nagarajan, Divya; Reeder, Stephen; Johnson, Catherine; Hood, Simon; Moseley, Paul M.; Chan, Stephen Y. T.; Pockley, A. Graham; Rutella, Sergio; McArdle, Stephanie E. B. 分享 收藏
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