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M

Michele Moschetta

AstraZeneca
H指数:51
被引数:7,087

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First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations

naporafenib (LXH254) 联合或不联合spartalizumab在患有MAPK信号通路改变的晚期实体瘤成年患者中的首次人体研究

EUROPEAN JOURNAL OF CANCER
IF7.1
2024-01-015
OA
Janku, Filip; Kim, Tae Min; Iyer, Gopakumar; Spreafico, Anna; Elez, Elena; de Jonge, Maja; Yamamoto, Noboru; van der Wekken, Anthonie J.; Ascierto, Paolo Antonio; Maur, Michela; Marme, Frederik; Kiladjian, Jean-Jacques; Basu, Sumit; Baffert, Fabienne; Buigues, Amparo; Chen, Chi; Cook, Vesselina; Giorgetti, Elisa; Kim, Jaeyeon; McCarthy, Fiona; Moschetta, Michele; Dummer, Reinhard
HRO761, a first-in-class, clinical stage WRN inhibitor with potent preclinical anti-tumor activity in MSIhigh models
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-011
PRE
Ferretti, Stephane; Jaco, Isabel; Decker, Andrea; Hemmerlin, Christelle; Scheufler, Clemens; Quadt, Cornelia; Sterker, Dario; Gavioli, Elena; Nunez, Eloisa Jimenez; Dammassa, Ernesta; Schaeffer, Fanny; Albrecht, Genevieve; Clementi, Giorgia; Martus, Hansjoerg; Hamon, Jacques; Hinrichs, Juergen; Laborde, Laurent; Dourdoigne, Marion; Moschetta, Michele; Stump, Ramona; Andraos-Rey, Rita; Welly, Sarah; Barbe, Stephanie; Romanet, Vincent; Reschke, Markus; De Kanter, Ruben; Jensen, Michael; Moebitz, Henrik; Cros, Marta Cortes
Discovery of HRO761, a novel, first-in-class clinical stage WRN inhibitor with potent and selective anti-tumor activity in cancers with microsatellite instability
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-013
PRE
Cortes-Cros, Marta; Moebitz, Henrik; Barbe, Stephanie; Blank, Jutta; Bordas, Vincent; Clementi, Giorgia; Dammassa, Ernesta; Decker, Andrea; Di Nanni, Noemi; de Kanter, Ruben; Dourdoigne, Marion; Gavioli, Elena; Ferretti, Stephane; Hattenberger, Marc; Hemmerlin, Christelle; Hamon, Jacques; Hinrichs, Juergen; Jaco, Isabel; Jankovic, Dragana; Nunez, Eloisa Jimenez; Li, Yifang; Martus, Hans-Joerg; Moschetta, Michele; Quadt, Cornelia; Reschke, Markus; Romanet, Vincent; Scheufler, Clemens; Schoepfer, Joseph; Strang, Ross; Therier, Maxime; Voshol, Hans; Wartmann, Markus; Welly, Sarah; Pham, Monica; Laborde, Laurent
A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development
CANCER DISCOVERY
IF33.3
2023-05-3046
OAAI
Dickinson, Michael J.; Barba, Pere; Jaeger, Ulrich; Shah, Nirav N.; Blaise, Didier; Briones, Javier; Shune, Leyla; Boissel, Nicolas; Bondanza, Attilio; Mariconti, Luisa; Marchal, Anne-Laure; Quinn, David S.; Yang, Jennifer; Price, Andrew; Sohoni, Akash; Treanor, Louise M.; Orlando, Elena J.; Mataraza, Jennifer; Davis, Jaclyn; Lu, Darlene; Zhu, Xu; Engels, Boris; Moutouh-de Parseval, Laure; Brogdon, Jennifer L.; Moschetta, Michele; Flinn, Ian W.
A View on Drug Development for Cancer Prevention
CANCER DISCOVERY
IF33.3
2023-04-176
OA
Reynolds, Andrew R.; Moschetta, Michele; Yohannes, Alula R.; Walcott, Farzana; Ashford, Marianne; Szucs, Zoltan; Sarbajna, Tina; Hadfield, James; Harrison, Eden; Challis, Benjamin G.; Hernandez, Amaya Gasco; Schiavon, Gaia; Germa, Caroline; Zorenyi, Gyorgy; Crean, Barry; Galbraith, Susan
Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer
NPJ BREAST CANCER
IF7.6
2021-04-1624
OAAI
Smyth, Lillian M.; Batist, Gerald; Meric-Bernstam, Funda; Kabos, Peter; Spanggaard, Iben; Lluch, Ana; Jhaveri, Komal; Varga, Andrea; Wong, Andrea; Schram, Alison M.; Ambrose, Helen; Carr, T. Hedley; de Bruin, Elza C.; Salinas-Souza, Carolina; Foxley, Andrew; Hauser, Joana; Lindemann, Justin P. O.; Maudsley, Rhiannon; McEwen, Robert; Moschetta, Michele; Nikolaou, Myria; Schiavon, Gaia; Razavi, Pedram; Banerji, Udai; Baselga, Jose; Hyman, David M.; Chandarlapaty, Sarat
Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-03-3011
OA
Carnevalli, Larissa S.; Taylor, Molly A.; King, Matthew; Coenen-Stass, Anna M. L.; Hughes, Adina M.; Bell, Sigourney; Proia, Theresa A.; Wang, Yanjun; Ramos-Montoya, Antonio; Wali, Neha; Carroll, Danielle; Singh, Maneesh; Moschetta, Michele; Gutierrez, Pablo Morentin; Gardelli, Cristina; Critchlow, Susan E.; Klinowska, Teresa; Fawell, Stephen E.; Barry, Simon T.
Capivasertib (AZD5363) in combination with fulvestrant in PTEN-mutant ER plus metastatic breast cancer
CANCER RESEARCH
IF16.6
2020-02-150
PRE
Smyth, Lillian M.; Batist, Gerald; Meric-Bernstam, Funda; Kabos, Peter; Spanggaard, Iben; Lluch, Ana; Schram, Alison; Varga, Andrea; Wong, Andrea; Ambrose, Helen; Barnicle, Alan; Carr, T. Hedley; de Bruin, Elza C.; Salinas-Souza, Carolina; Foxley, Andrew; Hauser, Joana; Lindemann, Justin P. O.; Maudsley, Rhiannon; McEwen, Robert; Moschetta, Michele; Roudier, Martine; Schiavon, Gaia; Razavi, Pedram; Banerji, Udai; Chandarlapaty, Sarat; Baselga, Jose; Hyman, David M.
A pre-surgical, window of opportunity study comparing the novel oral SERD AZD9496 with fulvestrant in patients with newly diagnosed ER+HER2-primary breast cancer
CANCER RESEARCH
IF16.6
2020-02-152
PRE
Robertson, John F. R.; Evans, Abigail; Henschen, Stephan; Kirwan, Cliona; Jahan, Ali; Kenny, Laura; Dixon, J. Michael; Schmid, Peter; Kothari, Ashutosh; Mohamed, Omar; Fasching, Peter A.; Cheung, Kwok-Leung; Wuerstlein, Rachel; Carroll, Danielle; Klinowska, Teresa; Lindemann, Justin P. O.; MacDonald, Alexander; Mather, Richard; Maudsley, Rhiannon; Moschetta, Michele; Nikolaou, Myria; Roudier, Martine P.; Sarvotham, Tinnu; Schiavon, Gaia; Zhou, Diansong; Zhou, Li; Harbeck, Nadia

研究方向

暂未获取到该数据
I
Irene M. Ghobrial
H 指数:99论文数:1,117被引数:4.5万
A
Aldo M. Roccaro
H 指数:63论文数:521被引数:1.2万
A
Antonio Sacco
H 指数:45论文数:360被引数:7,561
Y
Yuji Mishima
H 指数:36论文数:206被引数:4,063
S
Salomon Manier
H 指数:49论文数:415被引数:1.0万
S
Stergios Boussios
H 指数:48论文数:204被引数:5,672
M
Michaela R. Reagan
H 指数:40论文数:173被引数:6,757
A
Angelo Vacca
H 指数:82论文数:836被引数:3.0万
Y
Yawara Kawano
H 指数:24论文数:164被引数:2,482
S
Siobhan Glavey
H 指数:14论文数:37被引数:1,739