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J

Jan Wijnholds

leiden university medical center
H指数:56
被引数:1.2万

个人简介

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荣誉奖项

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CRB1-Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow-Up

CRB1相关遗传性视网膜变性：为期4年的前瞻性自然病史研究

Clinical and Experimental Ophthalmology
IF5.6
2026-08-060
OAAI
Jessica S. Karuntu; Xuan-Thanh-An Nguyen; Mays Talib; Mary J. van Schooneveld; Jan Wijnholds; Maria M. van Genderen; Jos Twisk; Nicoline E. Schalij-Delfos; Caroline C. W. Klaver; Ralph J. Florijn; Jacoline B. ten Brink; Magda A. Smoor; L. Ingeborgh van den Born; Carel B. Hoyng; Alberta A. H. J. Thiadens; Camiel J. F. Boon
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy
NATURE COMMUNICATIONS
IF15.7
2023-10-1817
OAAI
Riedmayr, Lisa Maria; Hinrichsmeyer, Klara Sonnie; Thalhammer, Stefan Bernhard; Mittas, David Manuel; Karguth, Nina; Otify, Dina Yehia; Boehm, Sybille; Weber, Valentin Johannes; Bartoschek, Michael David; Splith, Victoria; Bruemmer, Manuela; Ferreira, Raphael; Boon, Nanda; Woegenstein, Gabriele Maria; Grimm, Christian; Wijnholds, Jan; Mehlfeld, Verena; Michalakis, Stylianos; Fenske, Stefanie; Biel, Martin; Becirovic, Elvir
CRB1 is required for recycling by RAB11A+vesicles in human retinal organoids

CRB1是人类视网膜类器官中RAB11A囊泡再循环所必需的

STEM CELL REPORTS
IF5.1
2023-09-017
OAAI
Buck, Thilo M.; Quinn, Peter M. J.; Pellissier, Lucie P.; Mulder, Aat A.; Jongejan, Aldo; Lu, Xuefei; Boon, Nanda; Koot, Danielle; Almushattat, Hind; Arendzen, Christiaan H.; Vos, Rogier M.; Bradley, Edward J.; Freund, Christian; Mikkers, Harald M. M.; Boon, Camiel J. F.; Moerland, Perry D.; Baas, Frank; Koster, Abraham J.; Neefjes, Jacques; Berlin, Ilana; Jost, Carolina R.; Wijnholds, Jan
CRB1-Associated Retinal Dystrophies: A Anticipation of Future Clinical Trials
AMERICAN JOURNAL OF OPHTHALMOLOGY
IF4.2
2022-02-0125
OAAI
Nguyen, Xuan-thanh-an; Talib, Mays; van Schooneveld, Mary J.; Wijnholds, J. A. N.; van Genderen, Maria M.; Schalij-delfos, Nicoline E.; Klaver, Caroline C. W.; Talsma, Herman E.; Fiocco, Marta; Florijn, Ralph J.; ten Brink, Jacoline B.; Cremers, Frans P. M.; Meester-smoor, Magda A.; van den Born, L. Ingeborgh; Hoyng, Carel B.; Thiadens, Alberta A. H. J.; Bergen, Arthur A.; Boon, Camiel J. F.
Defining inclusion criteria and endpoints for clinical trials: a prospective cross-sectional study in CRB1-associated retinal dystrophies
ACTA OPHTHALMOLOGICA
IF2.8
2021-02-0214
OAAI
Talib, Mays; van Schooneveld, Mary J.; Wijnholds, Jan; van Genderen, Maria M.; Schalij-Delfos, Nicoline E.; Talsma, Herman E.; Florijn, Ralph J.; ten Brink, Jacoline B.; Cremers, Frans P. M.; Thiadens, Alberta A. H. J.; van den Born, L. Ingeborgh; Hoyng, Carel B.; Meester-Smoor, Magda A.; Bergen, Arthur A.; Boon, Camiel J. F.
Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Muller Glia Are Targets of AAV5
STEM CELL REPORTS
IF5.1
2019-05-0172
OAAI
Quinn, Peter M.; Buck, Thilo M.; Mulder, Aat A.; Ohonin, Charlotte; Alves, C. Henrique; Vos, Rogier M.; Bialecka, Monika; van Herwaarden, Tessa; van Dijk, Elon H. C.; Talib, Mays; Freund, Christian; Mikkers, Harald M. M.; Hoeben, Rob C.; Goumans, Marie-Jose; Boon, Camiel J. F.; Koster, Abraham J.; Lopes, Susana M. Chuva de Sousa; Jost, Carolina R.; Wijnholds, Jan
The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
2018-08-1344
OAAI
Talib, Mays; van Schooneveld, Mary J.; Van Cauwenbergh, Caroline; Wijnholds, Jan; ten Brink, Jacoline B.; Florijn, Ralph J.; Schalij-Delfos, Nicoline E.; Dagnelie, Gislin; van Genderen, Maria M.; De Baere, Elfride; Meester-Smoor, Magda A.; De Zaeytijd, Julie; Cremers, Frans P. M.; van den Born, L. Ingeborgh; Thiadens, Alberta A.; Hoyng, Carel B.; Klaver, Caroline C.; Leroy, Bart P.; Bergen, Arthur A.; Boon, Camiel J. F.

研究方向

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P
Piet Borst
H 指数:134论文数:621被引数:6.2万
J
Jan Klooster
H 指数:37论文数:114被引数:4,249
L
Lucie P. Pellissier
H 指数:24论文数:74被引数:1,592
A
Arthur A. Bergen
H 指数:64论文数:325被引数:1.5万
J
Jos H. Beijnen
H 指数:129论文数:1,778被引数:7.5万
P
Peter R. Wielinga
H 指数:29论文数:49被引数:5,202
P
Peter M. J. Quinn
H 指数:18论文数:60被引数:1,471
C
C. Henrique Alves
H 指数:20论文数:65被引数:1,711
M
Mays Talib
H 指数:14论文数:26被引数:663
M
Marcel de Haas
H 指数:29论文数:82被引数:7,656