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H

Holger Wille

university of alberta

48H指数
165论文数
1.0W被引数
收录论文 87
发表时间
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Attenuation of Tau-Mediated β-Amyloid1-42 Aggregation by Native PLGA Nanoparticles and Its Relevance to Alzheimer Disease PathologyPLGA纳米颗粒对Tau介导的β-淀粉样蛋白1-42聚集的减弱及其与阿尔茨海默病病理的相关性
errInternational Journal of Molecular Sciences
IF4.9
err2026-09-14
err0
errOAAI
errPallabi Sil Paul; Aliza Borenstein-Katz; Klinton Shmeit; Holger Wille; Satyabrata Kar
err分享
err收藏
Plasmonics-Enhanced Characterization of Cervid PrP (87-114) Fragment Aggregates in Solution等离激元增强的鹿朊蛋白(87-114)片段聚集物溶液表征
errJOURNAL OF BIOPHOTONICS
IF2.3
err2025-11-01
err0
errOAAI
errMidha, Shinki; Sriraman, Aishwarya; Dorosh, Lyudmyla; Wille, Holger; Stepanova, Maria
err分享
err收藏
Multiscale simulations of folded and intrinsically disordered region-containing protein condensates多尺度模拟：含有折叠区域和固有无序区域蛋白凝聚体
errBiophysical Journal
IF3.1
err2025-10-13
err0
PREAI
errLyudmyla Dorosh; Holger Wille; Maria Stepanova
err分享
err收藏
Design of zwitterionic fluorescent polymers for membrane protein solubilization into native nanodiscs设计用于将膜蛋白溶解到天然纳米盘中的两性离子荧光聚合物
errBiophysical Chemistry
IF2.2
err2025-07-09
err0
errOAAI
errMichael Overduin; Gestél C. Kuyler; Mansoore Esmaili; Catharine A. Trieber; Claudia Acevedo-Morantes; Alexander P. Orazietti; Rustem Shaykhutdinov; Rakesh K. Bhat; Tomisin Omotoso; Sabiha Tajammul; Mohammad Rahim; Sophie Zinn-Justin; Russell E. Bishop; R. Scott Prosser; Holger Wille; Bert Klumperman
err分享
err收藏
Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders
errBIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
err2024-04-09
err0
errOAAI
errFlores-Fernandez, Jose Miguel; Pesch, Verena; Sriraman, Aishwarya; Chimal-Juarez, Enrique; Amidian, Sara; Wang, Xiongyao; Duckering, Caleb; Fang, Andrew; Reithofer, Sara; Ma, Liang; Cortez, Leonardo M.; Sim, Valerie L.; Tamgueney, Gueltekin; Wille, Holger
err分享
err收藏
Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease
errBRAIN
IF11.7
err2024-03-01
err1
errOAAI
errPesch, Verena; Flores-Fernandez, Jose Miguel; Reithofer, Sara; Ma, Liang; Oezduezenciler, Pelin; Busch, Yannick; Sriraman, Aishwarya; Wang, YongLiang; Amidian, Sara; Kroepel, Chiara V. M.; Mueller, Laura; Lien, Yi; Rudtke, Olivia; Frieg, Benedikt; Schroeder, Gunnar F.; Wille, Holger; Tamgueney, Gueltekin
err分享
err收藏
SERS probing of fungal HET-s fibrils formed at neutral and acidic pH conditions
errSPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
IF4.6
err2024-03-01
err1
errOAAI
errWu, Min; Flores-Fernandez, Jose Miguel; Wang, Yongliang; Ahmed, Haseeb; Wille, Holger; Stepanova, Maria
err分享
err收藏
Protein thermal sensing regulates physiological amyloid aggregation
errNATURE COMMUNICATIONS
IF15.7
err2024-02-09
err1
errOAAI
errMarijan, Dane; Momchilova, Evgenia A.; Burns, Daniel; Chandhok, Sahil; Zapf, Richard; Wille, Holger; Potoyan, Davit A.; Audas, Timothy E.
err分享
err收藏
Native PLGA nanoparticles attenuate Aβ-seed induced tau aggregation under in vitro conditions: potential implication in Alzheimer's disease pathology
errSCIENTIFIC REPORTS
IF3.9
err2024-01-02
err5
errOAAI
errPaul, Pallabi Sil; Patel, Tark; Cho, Jae-Young; Yarahmady, Allan; Khalili, Aria; Semenchenko, Valentyna; Wille, Holger; Kulka, Marianna; Mok, Sue-Ann; Kar, Satyabrata
err分享
err收藏
Propagation of PrPSc in mice reveals impact of aggregate composition on prion disease pathogenesis
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-11-14
err2
errOAAI
errChang, Sheng Chun; Hannaoui, Samia; Arifin, Maria Immaculata; Huang, Yuan-Hung; Tang, Xinli; Wille, Holger; Gilch, Sabine
err分享
err收藏
Progress in vaccine development for infectious diseases-a Keystone Symposia report传染病疫苗开发的进展-Keystone专题讨论会报告
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2023-04-05
err4
PREAI
errCable, Jennifer; Graham, Barney S.; Koup, Richard A.; Seder, Robert A.; Kariko, Katalin; Pardi, Norbert; Barouch, Dan H.; Sharma, Bhawna; Rauch, Susanne; Nachbagauer, Raffael; Forsell, Mattias N. E.; Schotsaert, Michael; Ellebedy, Ali H.; Lore, Karin; Irvine, Darrell J.; Pilkington, Emily; Tahtinen, Siri; Thompson, Elizabeth A.; Feraoun, Yanis; King, Neil P.; Saunders, Kevin; Alter, Galit; Moin, Syed M.; Sliepen, Kwinten; Karlsson Hedestam, Gunilla B.; Wardemann, Hedda; Pulendran, Bali; Doria-Rose, Nicole A.; He, Wan-Ting; Juno, Jennifer A.; Ataca, Sila; Wheatley, Adam K.; McLellan, Jason S.; Walker, Laura M.; Lederhofer, Julia; Lindesmith, Lisa C.; Wille, Holger; Hotez, Peter J.; Bekker, Linda-Gail
err分享
err收藏
A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err45
errOAAI
errSupattapone, S; Bouzamondo, E; Ball, HL; Wille, H; Nguyen, HOB; Cohen, FE; DeArmond, SJ; Prusiner, SB; Scott, M
err分享
err收藏
Somatostatin slows Aβ plaque deposition in aged APPNL-F/NL-F mice by blocking Aβ aggregation
errSCIENTIFIC REPORTS
IF3.9
err2023-02-09
err3
errOAAI
errWilliams, Declan; Yan, Bei Qi; Wang, Hansen; Negm, Logine; Sackmann, Christopher; Verkuyl, Claire; Rezai-Stevens, Vanessa; Eid, Shehab; Vediya, Nimit; Sato, Christine; Watts, Joel C.; Wille, Holger; Schmitt-Ulms, Gerold
err分享
err收藏
Essential collective dynamics analysis reveals nonlocal interactions of alpha-synuclein38-95 monomers with fibrillar seeds
errJOURNAL OF CHEMICAL PHYSICS
IF3.1
err2022-12-21
err0
PREAI
errWu, Min; Wille, Holger; Stepanova, Maria
err分享
err收藏
Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology天然PLGA纳米粒在阿尔茨海默病病理治疗中的意义
errBIOACTIVE MATERIALS
IF20.3
err2022-11-01
err28
errOAAI
errAnand, Bibin; Wu, Qi; Nakhaei-Nejad, Maryam; Karthivashan, Govindarajan; Dorosh, Lyudmyla; Amidian, Sara; Dahal, Abhishek; Li, Xiuju; Stepanova, Maria; Wille, Holger; Giuliani, Fabrizio; Kar, Satyabrata
err分享
err收藏
Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-04-01
err5
errOAAI
errDaude, Nathalie; Lau, Agnes; Vanni, Ilaria; Kang, Sang-Gyun; Castle, Andrew R.; Wohlgemuth, Serene; Dorosh, Lyudmyla; Wille, Holger; Stepanova, Maria; Westaway, David
err分享
err收藏
Unconjugated PLGA nanoparticles attenuate temperature-dependent β-amyloid aggregation and protect neurons against toxicity: implications for Alzheimer's disease pathology未结合的PLGA纳米颗粒可减弱温度依赖性 β-淀粉样蛋白聚集并保护神经元免受毒性: 对阿尔茨海默氏病病理学的影响
errJOURNAL OF NANOBIOTECHNOLOGY
IF12.6
err2022-02-04
err22
errOAAI
errPaul, Pallabi Sil; Cho, Jae-Young; Wu, Qi; Karthivashan, Govindarajan; Grabovac, Emily; Wille, Holger; Kulka, Mariana; Kar, Satyabrata
err分享
err收藏
Mimosine functionalized gold nanoparticles (Mimo-AuNPs) suppress β-amyloid aggregation and neuronal toxicity
errBIOACTIVE MATERIALS
IF20.3
err2021-12-01
err21
errOAAI
errAnand, Bibin G.; Wu, Qi; Karthivashan, Govindarajan; Shejale, Kiran P.; Amidian, Sara; Wille, Holger; Kar, Satyabrata
err分享
err收藏
Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology
errDISEASE MODELS & MECHANISMS
IF3.3
err2021-10-26
err16
errOAAI
errWu, Qi; Cortez, Leonardo; Kamali-Jamil, Razieh; Sim, Valerie; Wille, Holger; Kar, Satyabrata
err分享
err收藏
Biosynthesis of Silver Nanoparticles Using Stenocereus queretaroensis Fruit Peel Extract: Study of Antimicrobial Activity使用queretaroensis果皮提取物生物合成银纳米颗粒: 抗菌活性的研究
errMATERIALS
IF3.2
err2021-08-12
err16
errOAAI
errPadilla-Camberos, Eduardo; Moises Sanchez-Hernandez, Ivan; Ricardo Torres-Gonzalez, Omar; Ramirez-Rodriguez, Patricia; Diaz, Emmanuel; Wille, Holger; Flores-Fernandez, Jose Miguel
err分享
err收藏

研究方向

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合作学者
合作期刊
B
Bruce L. Miller
H 指数: 201 · 论文数: 2.1K
S
Stuart L. Schreiber
H 指数: 166 · 论文数: 1.3K
M
Michael P. Lisanti
H 指数: 161 · 论文数: 800
J
Jonathan S. Weissman
H 指数: 157 · 论文数: 553
S
Stanley B. Prusiner
H 指数: 155 · 论文数: 653
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