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J

John Troutman

Procter & Gamble

H指数:15

被引数:996

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Enhancement of Skin Permeability Prediction through PBPK Modeling, Bayesian Inference, and Experiment Design

通过PBPK建模，贝叶斯推理和实验设计增强皮肤渗透性预测

IF5.5

2023-11-241

OAAI

Mechanistic Skin Modeling of Plasma Concentrations of Sunscreen Active Ingredients Following Facial Application

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2023-09-015

OAAI

Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment

使用体外代谢和生物动力学测定来改进预测的体内和体外内部暴露于化妆品成分苯氧乙醇，用于风险评估

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2022-06-0111

OAAI

A Mechanistic Bayesian Inferential Workflow for Estimation of In Vivo Skin Permeation from In Vitro Measurements

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2022-03-018

PRE

Cosmetics Europe evaluation of 6 in silico skin penetration models

COMPUTATIONAL TOXICOLOGY

IF2.9

2021-08-0120

OAAI

Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2021-06-0114

PREAI

Assessment of Vehicle Volatility and Deposition Layer Thickness in Skin Penetration Models

IF5.5

2021-05-2811

OAAI

Refinement of the Peroxidase Peptide Reactivity Assay and Prediction Model for Assessing Skin Sensitization Potential

用于评估皮肤致敏潜能的过氧化物酶肽反应性测定和预测模型的改进

TOXICOLOGICAL SCIENCES

IF4.1

2020-09-108

OAAI

Intrinsic relative potency of a series of pyrrolizidine alkaloids characterized by rate and extent of metabolism

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2019-09-0125

PREAI

Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment

REGULATORY TOXICOLOGY AND PHARMACOLOGY

IF3.5

2015-11-0128

PREAI

Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2015-09-0119

OAAI

Estimation of in vivo dose of dermally applied chemicals leading to estrogen/androgen receptor-mediated toxicity from in vitro data-Illustration with four reproductive toxicants

REPRODUCTIVE TOXICOLOGY

IF2.8

2015-08-019

PREAI

Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2014-02-0155

PRE

The Incorporation of Lysine into the Peroxidase Peptide Reactivity Assay for Skin Sensitization Assessments

TOXICOLOGICAL SCIENCES

IF4.1

2011-05-0959

OAAI

Investigation of Peptide Reactivity of Pro-hapten Skin Sensitizers Using a Peroxidase-Peroxide Oxidation System

TOXICOLOGICAL SCIENCES

IF4.1

2009-09-11121

OAAI