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M

Milan G. Chheda

washington university in st louis
H指数:32
被引数:7,420

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Siglec-15 and PD-1 checkpoint blockade in combination with oncolytic Zika virus infection confers protection against immune-resistant gliomas

Siglec-15和PD-1检查点阻断与溶瘤寨卡病毒感染联合应用可对抗免疫抵抗性胶质瘤

Neuro-Oncology
IF13.4
2026-08-080
PRE
Ashwani Kesarwani; Amber S Griffith; Sonam Verma; Tong Hu; Fei Shu; Amanda De Andrade Costa; Yuping Derek Li; Mridu Kanga; Brett H Herzog; David G DeNardo; Mai T Dang; Jingqin Luo; Pei-Yong Shi; Xuping Xie; Jun Wang; Lieping Chen; Albert H Kim; Peggy L Kendall; Michael S Diamond; Milan G Chheda
Laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a Phase 1/randomized Phase 2b trial

激光间质热疗联合辅助帕博利珠单抗治疗复发性高级别星形细胞瘤：一项1期/随机2b期试验

Nature Communications
IF15.7
2026-02-260
OAAI
Jian L. Campian; Son B. Le; Ashley Ghiaseddin; Omar H. Butt; Harshit Manektalia; Dongjiang Chen; Yifei Xu; Jingxia Liu; Maryam Rahman; Nathan Thai; William A. Leidig; Tanner Johanns; George Ansstas; Alice Y. Zhou; Sangami Pugazenthi; Gavin P. Dunn; Jiayi Huang; Milan G. Chheda; Albert H. Kim; Eric C. Leuthardt; David D. Tran
Intracranial injection of genetically modified, mosquito non-transmissible Zika virus: Safety in primates and ramifications for brain tumor therapy

颅内注射经基因改造的、对蚊子非传染性的寨卡病毒：在灵长类动物中的安全性及对脑肿瘤治疗的启示

Cell Reports Medicine
IF10.6
2025-12-160
OAAI
Alec J. Hirsch; Amanda de Andrade Costa; Cody German; Christopher J. Parkins; Jessica L. Smith; Emilie Russler-Germain; Ashwani Kesarwani; Yuping Li; Verginia Cuzon Carlson; Timothy Carlson; Jodi L. McBride; Sathya Srinivasan; Anne D. Lewis; Xuping Xie; Pei-Yong Shi; Michael S. Diamond; Milan G. Chheda
Diffusely metastatic glioblastoma with FGFR3::TACC3 fusion: cell-free DNA fragmentation analyses and molecular characterization of matched primary and metastatic tumor sites

弥漫性转移性胶质母细胞瘤伴FGFR3::TACC3融合：游离DNA片段化分析和匹配的原发及转移肿瘤病灶的分子特征分析

Acta Neuropathologica Communications
IF5.7
2025-11-030
OAAI
Miguel A. Hernandez-Rovira; Alicia Vagnozzi; Tyler Bales; Keerthana N. Prabhu; Noushin Niknafs; Milan Chheda; Jiayi Huang; Albert H. Kim; Michelle Miller-Thomas; Omar Butt; Katie D. Vo; Bhargavi S. Sovani; Ashwin Singh Parihar; Suzanne Crumley; Sonika Dahiya; Dimitrios Mathios
PERSONALIZED MULTIVALENT DNA VACCINATION SAFELY INDUCES BROAD NEOANTIGEN-SPECIFIC T CELL RESPONSES IN NEWLY DIAGNOSED MGMT UNMETHYLATED GLIOBLASTOMA IN A CLINICALLY RELEVANT TIME SCALE

个性化多价DNA疫苗接种安全地诱导新诊断的MGMT未甲基化胶质母细胞瘤中广泛的 neoantigen特异性T细胞反应，在临床上相关的时间尺度内。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Garfinkle, Elizabeth; Perales-Linares, Renzo; Gimple, Ryan; Yan, Jian; Navarro, Jaye; Paxton, Sophia; Livingstone, Alexandra; Roberts, Kaleigh; Cooch, Neil; Perales-Puchalt, Alfredo; Rochestie, Sarah; Peters, Joann; Campian, Jian; Junker, Beth; Chheda, Milan; Chicoine, Michael; Kim, Albert; Willie, Jon; Zipfel, Gregory; Dowling, Joshua; Gillanders, William; Miller, Katherine; Mardis, Elaine; Sardesai, Niranjan; Dunn, Gavin; Johanns, Tanner
LASER INTERSTITIAL THERMAL THERAPY PLUS PEMBROLIZUMAB PROLONGS SURVIVAL AND ELICITS ROBUST ANTI-TUMOR IMMUNITY IN RECURRENT, REFRACTORY HIGH-GRADE ASTROCYTOMA: A PHASE 1/RANDOMIZED PHASE 2B TRIAL

激光间质热疗联合帕博利珠单抗延长复发性难治性高级别星形细胞瘤的生存期并诱导强烈的抗肿瘤免疫反应：一项1期/随机2b期试验

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Tran, David; Campian, Jian; Le, Son; Ghiaseddin, Ashley; Butt, Omar; Manektalia, Harshit; Chen, Dongjiang; Rahman, Maryam; Chheda, Milan; Kim, Albert; Leuthardt, Eric
Dual blockade of Siglec-15 and PD-1, combined with oncolytic Zika virus therapy, confers protection against immune-resistant gliomas

联合使用Siglec-15和PD-1的双阻断疗法，结合溶瘤寨卡病毒疗法，能够对抗免疫抵抗性胶质瘤的保护作用。

NEURO-ONCOLOGY
IF13.4
2025-11-010
PRE
Kesarwani, Ashwani; Verma, Sonam; Griffith, Amber Neil; Hu, Tong; Shu, Fei; De Costa, Amanda Andrade; Li, Yuping Derek; Kanga, Mridu; Herzog, Brett H.; DeNardo, David G.; Dang, Mai; Luo, Jingqin; Shi, Pei-Yong; Xie, Xuping; Wang, Jun; Chen, Lieping; Kim, Albert; Kendall, Peggy; Diamond, Michael S.; Chheda, Milan G.
Phase I study of NT-I7, a long-acting interleukin-7, in severe treatment-related lymphopenia following standard radiation and temozolomide for high-grade glioma

I期研究：NT-I7（一种长效白介素-7）在标准放疗和替莫唑胺治疗高级别胶质瘤后严重治疗相关性淋巴细胞减少中的应用

NEURO-ONCOLOGY ADVANCES
IF4.1
2025-01-011
OA
Campian, Jian L.; Grossman, Stuart A.; Kask, Angela Shaulov; Kosydar, Samuel; Strowd, Roy; Piotrowski, Anna; Tang, Justin; Chheda, Milan G.; Dipersio, John F.; Schullery, Dan; D'Amico, Leonard; Desideri, Serena; Danda, Neeraja; Ferrando-Martinez, Sara; Lee, Byung Ha; Fling, Steven P.; Ye, Xiaobu
A PHASE II STUDY OF RETIFANLIMAB (PD-1 INHIBITOR) AND EPACADOSTAT (IDO1 INHIBITOR) IN COMBINATION WITH BEVACIZUMAB AND HYPOFRACTIONATED RADIOTHERAPY FOR RECURRENT GLIOBLASTOMA: NCT03532295
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Butt, Abeer; Luo, Jingqin; Tao, Yu; Butt, Omar; Etter, Kelsey; Nehring, Leslie; Hissim, Deanna; Mckean, Cole; Ansstas, George; Kim, Albert; Abraham, Christopher; Kizilbash, Sani; Strowd, Roy; Johanns, Tanner; Huang, Jiayi; Ciorba, Matthew; Campian, Jian; Chheda, Milan
NT-I7, A LONG-ACTING INTERLEUKIN-7, PROMOTES ACTIVATION, CYTOTOXIC FUNCTION, AND SELECTIVE CLONOTYPE EXPANSION OF CD8+T CELLS IN PATIENTS WITH HIGH GRADE GLIOMAS
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Barozinsky, Kaiden; Foltz, Jennifer A.; Butt, Omar H.; Zhou, Alice Y.; Singhal, Kartik; Griffith, Obi; Griffith, Malachi; Etter, Kelsey; Grote, Cierra; Luo, Jingqin; Nehring, Leslie; Katumba, Ruth; Ferrando-Martinez, Sara; Stermer, Kristina; Lee, Byung Ha; Johanns, Tanner; Huang, Jiayi; Dipersio, John; Chheda, Milan; Fehniger, Todd; Campian, Jian L.
A Phase 1/2 Study of Disulfiram and Copper With Concurrent Radiation Therapy and Temozolomide for Patients With Newly Diagnosed Glioblastoma

双硫仑和铜联合放射治疗和替莫唑胺对新诊断的胶质母细胞瘤患者的1/2期研究

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
2024-11-012
PRE
Huang, Jiayi; Campian, Jian L.; Dewees, Todd A.; Skrott, Zdenek; Mistrik, Martin; Johanns, Tanner M.; Ansstas, George; Butt, Omar; Leuthardt, Eric; Dunn, Gavin P.; Zipfel, Gregory J.; Osbun, Joshua W.; Abraham, Christopher; Badiyan, Shahed; Schwetye, Katherine; Cairncross, J. Gregory; Rubin, Joshua B.; Kim, Albert H.; Chheda, Milan G.
Tumour evolution and microenvironment interactions in 2D and 3D space

2D和3D空间中的肿瘤进化和微环境相互作用

Nature
IF48.5
2024-10-300
OAAI
Chia-Kuei Mo; Jingxian Liu; Siqi Chen; Erik Storrs; Andre Luiz N. Targino da Costa; Andrew Houston; Michael C. Wendl; Reyka G. Jayasinghe; Michael D. Iglesia; Cong Ma; John M. Herndon; Austin N. Southard-Smith; Xinhao Liu; Jacqueline Mudd; Alla Karpova; Andrew Shinkle; S. Peter Goedegebuure; Abdurrahman Taha Mousa Ali Abdelzaher; Peng Bo; Lauren Fulghum; Samantha Livingston; Metin Balaban; Angela Hill; Joseph E. Ippolito; Vesteinn Thorsson; Jason M. Held; Ian S. Hagemann; Eric H. Kim; Peter O. Bayguinov; Albert H. Kim; Mary M. Mullen; Kooresh I. Shoghi; Tao Ju; Melissa A. Reimers; Cody Weimholt; Liang-I Kang; Sidharth V. Puram; Deborah J. Veis; Russell Pachynski; Katherine C. Fuh; Milan G. Chheda; William E. Gillanders; Ryan C. Fields; Benjamin J. Raphael; Feng Chen; Li Ding
Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages

差异染色质可及性和转录动力学定义乳腺癌亚型及其谱系

NATURE CANCER
IF28.5
2024-10-301
OAAI
Iglesia, Michael D.; Jayasinghe, Reyka G.; Chen, Siqi; Terekhanova, Nadezhda V.; Herndon, John M.; Storrs, Erik; Karpova, Alla; Zhou, Daniel Cui; Al Deen, Nataly Naser; Shinkle, Andrew T.; Lu, Rita Jui-Hsien; Caravan, Wagma; Houston, Andrew; Zhao, Yanyan; Sato, Kazuhito; Lal, Preet; Street, Cherease; Rodrigues, Fernanda Martins; Southard-Smith, Austin N.; da Costa, Andre Luiz N. Targino; Zhu, Houxiang; Mo, Chia-Kuei; Crowson, Lisa; Fulton, Robert S.; Wyczalkowski, Matthew A.; Fronick, Catrina C.; Fulton, Lucinda A.; Sun, Hua; Davies, Sherri R.; Appelbaum, Elizabeth L.; Chasnoff, Sara E.; Carmody, Madelyn; Brooks, Candace; Liu, Ruiyang; Wendl, Michael C.; Oh, Clara; Bender, Diane; Cruchaga, Carlos; Harari, Oscar; Bredemeyer, Andrea; Lavine, Kory; Bose, Ron; Margenthaler, Julie; Held, Jason M.; Achilefu, Samuel; Ademuyiwa, Foluso; Aft, Rebecca; Ma, Cynthia; Colditz, Graham A.; Ju, Tao; Oh, Stephen T.; Fitzpatrick, James; Hwang, E. Shelley; Shoghi, Kooresh I.; Chheda, Milan G.; Veis, Deborah J.; Chen, Feng; Fields, Ryan C.; Gillanders, William E.; Ding, Li
Epigenetic regulation during cancer transitions across 11 tumour types
Nature
IF48.5
2023-11-010
OAAI
Nadezhda V. Terekhanova; Alla Karpova; Wen-Wei Liang; Alexander Strzalkowski; Siqi Chen; Yize Li; Austin N. Southard-Smith; Michael D. Iglesia; Michael C. Wendl; Reyka G. Jayasinghe; Jingxian Liu; Yizhe Song; Song Cao; Andrew Houston; Xiuting Liu; Matthew A. Wyczalkowski; Rita Jui-Hsien Lu; Wagma Caravan; Andrew Shinkle; Nataly Naser Al Deen; John M. Herndon; Jacqueline Mudd; Cong Ma; Hirak Sarkar; Kazuhito Sato; Omar M. Ibrahim; Chia-Kuei Mo; Sara E. Chasnoff; Eduard Porta-Pardo; Jason M. Held; Russell Pachynski; Julie K. Schwarz; William E. Gillanders; Albert H. Kim; Ravi Vij; John F. DiPersio; Sidharth V. Puram; Milan G. Chheda; Katherine C. Fuh; David G. DeNardo; Ryan C. Fields; Feng Chen; Benjamin J. Raphael; Li Ding

研究方向

暂未获取到该数据
A
Albert H. Kim
H 指数:55论文数:931被引数:1.1万
J
Jian Campian
H 指数:40论文数:274被引数:7,301
O
Omar H. Butt
H 指数:23论文数:112被引数:2,283
T
Tanner M. Johanns
H 指数:29论文数:832被引数:3,698
G
George Ansstas
H 指数:24论文数:161被引数:3,374
J
Jiayi Huang
H 指数:48论文数:360被引数:7,151
E
Eric C. Leuthardt
H 指数:64论文数:404被引数:1.4万
李丁 封面图
李丁
H 指数:135论文数:1,113被引数:12.4万
Jingqin Luo 封面图
Jingqin Luo
H 指数:57论文数:714被引数:1.6万
R
Reyka G. Jayasinghe
H 指数:46论文数:233被引数:2.0万