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M

Mariangela Figini

istituto nazionale dei tumori
H指数:32
被引数:3,655

个人简介

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教育背景

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工作经历

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荣誉奖项

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Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production

通过工艺开发和良好生产规范生产，对首个同类抗肿瘤IgE抗体药物MOv18进行理化性质和功能评价

MABS
IF7.3
2025-01-201
OA
Heather J Bax; Jitesh Chauhan; Alexandra J McCraw; Melanie Grandits; Chara Stavraka; Heike Lentfer; Tim Hillyer; Simon Carroll; Kim Vigor; Chris Selkirk; Mariangela Figini; Jack Cheeseman; Paulina A Urbanowicz; Richard A Gardner; Daniel I R Spencer; Nigel Westwood; Sarah Mellor; James Spicer; Debra H Josephs; Sophia N Karagiannis
Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial
NATURE COMMUNICATIONS
IF15.7
2023-07-258
OAAI
Spicer, James; Basu, Bristi; Montes, Ana; Banerji, Udai; Kristeleit, Rebecca; Miller, Rowan; Veal, Gareth J. J.; Corrigan, Christopher J. J.; Till, Stephen J. J.; Figini, Mariangela; Canevari, Silvana; Barton, Claire; Jones, Paul; Mellor, Sarah; Carroll, Simon; Selkirk, Chris; Nintos, George; Kwatra, Vineet; Funingana, Ionut-Gabriel; Doherty, Gary; Gould, Hannah J. J.; Pellizzari, Giulia; Nakamura, Mano; Ilieva, Kristina M. M.; Khiabany, Atousa; Stavraka, Chara; Chauhan, Jitesh; Gillett, Cheryl; Pinder, Sarah; Bax, Heather J. J.; Josephs, Debra H. H.; Karagiannis, Sophia N. N.
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
BRITISH JOURNAL OF CANCER
IF6.8
2022-11-1937
OA
Bax, Heather J.; Chauhan, Jitesh; Stavraka, Chara; Santaolalla, Aida; Osborn, Gabriel; Khiabany, Atousa; Grandits, Melanie; Lopez-Abente, Jacobo; Palhares, Lais C. G. F.; Hak, Charleen Chan Wah; Robinson, Alexandra; Pope, Amy; Woodman, Natalie; Naceur-Lombardelli, Cristina; Malas, Sadek; Coumbe, Jack E. M.; Nakamura, Mano; Laddach, Roman; Mele, Silvia; Crescioli, Silvia; Black, Anna M.; Lombardi, Sara; Canevari, Silvana; Figini, Mariangela; Sayasneh, Ahmad; Tsoka, Sophia; FitzGerald, Kevin; Gillett, Cheryl; Pinder, Sarah; Van Hemelrijck, Mieke; Kristeleit, Rebecca; Ghosh, Sharmistha; Montes, Ana; Spicer, James; Karagiannis, Sophia N.; Josephs, Debra H.
FIRST-IN-HUMAN PHASE I CLINICAL TRIAL EVALUATING INTRAPERITONEAL ADMINISTRATION OF MOV19-BBZ CAR T CELLS IN PATIENTS WITH ALPHA FOLATE RECEPTOR-EXPRESSING RECURRENT HIGH GRADE SEROUS OVARIAN CANCER
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2021-11-103
OA
Shah, Payal; Shlanksy-Goldberg, Richard; Martin, Lainie; Nadolski, Gregory; Hexner, Elizabeth; Shamimi-Noori, Susan; Hwang, Wei-Ting; Matlawski, Tina; Cervini, Amanda; Shea, Joanne; Nelson, Lauren; Lacey, Simon; Plesa, Gabriela; Lledo, Lester; Dengel, Karen; Marshall, Amy; Leskowitz, Rachel; Kandalaft, Lana; Figini, Mariangela; Canevari, Silvana; Coukos, George; Powell, Daniel
Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2021-06-1016
OAAI
Pellizzari, Giulia; Martinez, Olivier; Crescioli, Silvia; Page, Robert; Di Meo, Ashley; Mele, Silvia; Chiaruttini, Giulia; Hoinka, Jan; Batruch, Ihor; Prassas, Ioannis; Grandits, Melanie; Lopez-Abente, Jacobo; Bugallo-Blanco, Eva; Ward, Malcolm; Bax, Heather J.; French, Elise; Cheung, Anthony; Lombardi, Sara; Figini, Mariangela; Lacy, Katie E.; Diamandis, Eleftherios P.; Josephs, Debra H.; Spicer, James; Papa, Sophie; Karagiannis, Sophia N.
Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)
SCIENTIFIC REPORTS
IF3.9
2020-06-0115
OAAI
Hoffmann, Ricarda M.; Mele, Silvia; Cheung, Anthony; Larcombe-Young, Daniel; Bucaite, Gintare; Sachouli, Eirini; Zlatareva, Iva; Morad, Hassan O. J.; Marlow, Rebecca; McDonnell, James M.; Figini, Mariangela; Lacy, Katie E.; Tutt, Andrew J. N.; Spicer, James F.; Thurston, David E.; Karagiannis, Sophia N.; Crescioli, Silvia
Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer
CLINICAL CANCER RESEARCH
IF10.2
2018-10-1568
OAAI
Cheung, Anthony; Opzoomer, James; Ilieva, Kristina M.; Gazinska, Patrycja; Hoffmann, Ricarda M.; Mirza, Hasan; Marlow, Rebecca; Francesch-Domenech, Erika; Fittall, Matthew; Rodriguez, Diana Dominguez; Clifford, Angela; Badder, Luned; Patel, Nirmesh; Mele, Silvia; Pellizzari, Giulia; Bax, Heather J.; Crescioli, Silvia; Petranyi, Gyula; Larcombe-Young, Daniel; Josephs, Debra H.; Canevari, Silvana; Figini, Mariangela; Pinder, Sarah; Nestle, Frank O.; Gillett, Cheryl; Spicer, James F.; Grigoriadis, Anita; Tutt, Andrew N. J.; Karagiannis, Sophia N.
An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE
ALLERGY
IF12
2018-10-0823
OAAI
Josephs, D. H.; Nakamura, M.; Bax, H. J.; Dodev, T. S.; Muirhead, G.; Saul, L.; Karagiannis, P.; Ilieva, K. M.; Crescioli, S.; Gazinska, P.; Woodman, N.; Lombardelli, C.; Kareemaghay, S.; Selkirk, C.; Lentfer, H.; Barton, C.; Canevari, S.; Figini, M.; Downes, N.; Dombrowicz, D.; Corrigan, C. J.; Nestle, F. O.; Jones, P. S.; Gould, H. J.; Blower, P. J.; Tsoka, S.; Spicer, J. F.; Karagiannis, S. N.

研究方向

暂未获取到该数据
S
Silvana Canevari
H 指数:56论文数:411被引数:1.1万
J
James Spicer
H 指数:67论文数:566被引数:1.5万
S
Sophia N. Karagiannis
H 指数:52论文数:350被引数:7,779
E
Elena Luison
H 指数:16论文数:48被引数:654
D
Delia Mezzanzanica
H 指数:41论文数:171被引数:5,168
B
Barbara Frigerio
H 指数:8论文数:18被引数:293
S
Silvia Crescioli
H 指数:28论文数:117被引数:3,273
D
Debra H. Josephs
H 指数:41论文数:218被引数:5,095
H
Heather J. Bax
H 指数:30论文数:107被引数:2,953
S
Silvia Mele
H 指数:21论文数:82被引数:1,779