Seán O. Hynes - Publications, H-index & Citations

Seán O. Hynes

School of Medicine

28H指数

126论文数

2.8K被引数

收录论文 43

发表时间

Intravenous delivery of mesenchymal stromal cells reverses Müller cell endoplasmic reticulum stress in diabetic retinopathy 静脉输注间充质基质细胞可逆转糖尿病视网膜病变中的 Müller 细胞内质网应激

Stem Cell Research & Therapy

IF7.3

2025-12-27

OAAI

Wei Yan; Ruiyun Guo; Tong Liu; Yukun Liu; Rui Ping; Boxin Liu; Jingjing He; Matthew D. Griffin; Seán O. Hynes; Sanbing Shen; Yan Liu; Jun Ma; Timothy O’Brien

Improving Options and Access for People With a Substance Use Disorder: A Service Evaluation of a Novel Nurse Practitioner-Led Ambulatory Model of Care for Withdrawal Management 改善物质使用障碍患者的选择与可及性：一项关于新型护士主导型门诊戒断管理护理模式的服务评估

Drug and Alcohol Review

IF2.6

2025-10-13

PREAI

Carol Reid; Jeanine Young; Darren Smyth; Adam Searby; Mary Fenech; Sean Hynes; Katharina Merollini; Joshua Knowles

The Tumour Glyco-Code: Sialylation as a Mediator of Stromal Cell Immunosuppression in the Tumour Microenvironment 肿瘤糖密码：唾液酸化作为肿瘤微环境中基质细胞免疫抑制的介导因素

European Journal of Immunology

IF3.7

2025-07-16

OAAI

Aoise O'Neill; Norashikin Zakaria; Hannah Egan; Oliver Treacy; Aisling M. Hogan; Michael O'Dwyer; Sean O. Hynes; Aideen E. Ryan

Calcified Coronary Artery Disease: Pathology, Prevalence, Predictors and Impact on Outcomes 钙化冠状动脉疾病：病理学、患病率、预测因子及对预后的影响

INTERVENTIONAL CARDIOLOGY-REVIEWS RESEARCH RESOURCES

IF2.8

2025-02-14

OAAI

Mcinerney, Angela; Hynes, Sean O.; Gonzalo, Nieves

Mesenchymal stromal cell transplantation ameliorates fibrosis and microRNA dysregulation in skeletal muscle ischemia

Stem Cells

IF3.6

2024-09-16

OAAI

Sanz-Nogues, Clara; Keane, Alan J.; Creane, Michael; Hynes, Sean O.; Chen, Xizhe; Lyons, Caomhan J.; Horan, Emma; Elliman, Stephen J.; Goljanek-Whysall, Katarzyna; O'Brien, Timothy

Client and stakeholder perceptions of a novel, nurse practitioner-led alcohol and other drug ambulatory withdrawal service

DRUG AND ALCOHOL REVIEW

IF2.6

2024-06-03

OAAI

Searby, Adam; Burr, Dianna; Reid, Carol; Smyth, Darren; Hynes, Sean; Fenech, Mary; Merollini, Katharina; Young, Jeanine

Human umbilical cord-derived mesenchymal stromal cells improve myocardial fibrosis and restore miRNA-133a expression in diabetic cardiomyopathy

STEM CELL RESEARCH & THERAPY

IF7.3

2024-04-24

OAAI

Liu, Boxin; Wei, Yan; He, Jingjing; Feng, Baofeng; Chen, Yimeng; Guo, Ruiyun; Griffin, Matthew D.; Hynes, Sean O.; Shen, Sanbing; Liu, Yan; Cui, Huixian; Ma, Jun; O'Brien, Timothy

Targeting NOS2 and the tumor microenvironment in endometrioid ovarian cancer: Implications for treatment and survival

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Melone, Gianmarco; Li, Mailin; Uzair, Ivonne; Chervo, Maria; Ortega, Karina; Qian, Wei; Zhou, Jianying; Guzman, Liliana; Hynes, Sean; Glynn, Sharon; Thomas, Christoforos; Matre, Polina; Francis, Lewis; Chang, Jenny

Amelioration of diabetic nephropathy in mice by a single intravenous injection of human mesenchymal stromal cells at early and later disease stages is associated with restoration of autophagy

STEM CELL RESEARCH & THERAPY

IF7.3

2024-03-05

OAAI

He, Jingjing; Liu, Boxin; Du, Xiaofeng; Wei, Yan; Kong, Desheng; Feng, Baofeng; Guo, Ruiyun; Asiamah, Ernest Amponsah; Griffin, Matthew D.; Hynes, Sean O.; Shen, Sanbing; Liu, Yan; Cui, Huixian; Ma, Jun; O'Brien, Timothy

The strategic use of biopsy in the diagnosis of coeliac disease in adults

DIGESTIVE AND LIVER DISEASE

IF3.8

2023-12-01

PREAI

Deane, Charlene; O'Connor, Eoghan; O'Donovan, Helen; McHale, Ciaran; Alvain, Aoife; Shannon, Eileen; Tormey, Vincent; Hynes, Sean O.; Byrnes, Valerie

Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

CELL REPORTS

IF6.9

2023-05-01

OAAI

Egan, Hannah; Treacy, Oliver; Lynch, Kevin; Leonard, Niamh A.; O'Malley, Grace; Reidy, Eileen; O'Neill, Aoise; Corry, Shania M.; De Veirman, Kim; Vanderkerken, Karin; Egan, Laurence J.; Ritter, Thomas; Hogan, Aisling M.; Redmond, Keara; Peng, Li; Che, Jenny; Gatlin, Wayne; Jayaraman, Pushpa; Sheehan, Margaret; Canney, Aoife; Hynes, Sean O.; Kerr, Emma M.; Dunne, Philip D.; O'Dwyer, Michael E.; Ryan, Aideen E.

Development and Validation of a Multiparametric Semiquantitative Scoring System for the Histopathological Assessment of Ischaemia Severity in Skeletal Muscle

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

IF2.6

2023-03-16

OAAI

Sanz-Nogues, Clara; Creane, Michael; Hynes, Sean O.; Chen, Xizhe; Lagonda, Christine Ayu; Goljanek-Whysall, Katarzyna; O'Brien, Timothy

Human endogenous retrovirus-K (HERV-K) is aberrantly expressed in triple negative breast cancer (TNBC) and associated with increased distant metastasis: Impact of HERV-K knockdown on gene expression patterns and invasive potential of mesenchymal TNBC

CANCER RESEARCH

IF16.6

2022-02-15

PREAI

Glynn, Sharon A.; Bhattacharyya, Dibyangana; Lambe, Shauna; Kerr, Emma; McDade, Simon; Khan, Faizan H.; Dervan, Eoin; Wang-Johanning, Feng; Hynes, Sean; Callagy, Grace

Inflammation-specific targeted carriers for local drug delivery to inflammatory bowel disease

BIOMATERIALS

IF12.9

2022-02-01

OAAI

Kotla, Niranjan G.; Singh, Rajbir; Baby, Becca, V; Rasala, Swetha; Rasool, Jawad; Hynes, Sean O.; Martin, Darrell; Egan, Laurence J.; Vemula, Praveen K.; Jala, Venkatakrishna R.; Rochev, Yury; Pandit, Abhay

SUGAR HIGH: DOES THE SIALIC ACID PROFILE OF CANCER-ASSOCIATED FIBROBLASTS INDUCE A MORE TUMOUR-PERMISSIVE MICROENVIRONMENT?

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-12-10

PREAI

Egan, Hannah; Treacy, Oliver; Lynch, Kevin; Leonard, Niamh; Nader, Amir; Sheehan, Margaret; Hynes, Sean; Egan, Laurence; Ritter, Thomas; Daly, John; Hogan, Aisling; Michael, O.; Ryan, Aideen

MDM2 amplification and hyperprogression following treatment with immune checkpoint inhibitors in advanced non-small cell lung cancer

ANNALS OF ONCOLOGY

IF65.4

2020-09-01

OAAI

Cowzer, D.; Blazkova, S.; Henry, S.; Donnellan, P.; Hynes, S.

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy

ANNALS OF ONCOLOGY

IF65.4

2018-01-01

OAAI

Jain, S.; Lyons, C. A.; Walker, S. M.; McQuaid, S.; Hynes, S. O.; Mitchell, D. M.; Pang, B.; Logan, G. E.; McCavigan, A. M.; O'Rourke, D.; McArt, D. G.; McDade, S. S.; Mills, I. G.; Prise, K. M.; Knight, L. A.; Steele, C. J.; Medlow, P. W.; Berge, V.; Katz, B.; Loblaw, D. A.; Harkin, D. P.; James, J. A.; O'Sullivan, J. M.; Kennedy, R. D.; Waugh, D. J.

A Metastatic Biology Gene Expression Assay to Predict the Risk of Distant Metastases in Patients With Localized Prostate Cancer Treated With Primary Radical Treatment

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2017-10-01

OAAI

Jain, S.; Lyons, C.; Walker, S.; McQuaid, S.; Hynes, S.; Mitchell, D.; Pang, B.; Logan, G.; McCavigan, A.; O'Rourke, D.; Davidson, C.; Knight, L.; Berge, V.; Neal, D.; Pandha, H.; Harkin, P.; James, J.; Kennedy, R.; O'Sullivan, J.; Waugh, D.

IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer

CELL DEATH DISCOVERY

IF7

2017-08-14

OAAI

Hutchinson, Ryan A.; Coleman, Helen G.; Gately, Kathy; Young, Vincent; Nicholson, Siobhan; Cummins, Robert; Kayo, Elaine; Hynes, Sean O.; Dunne, Philip D.; Senevirathne, Seedevi; Hamilton, Peter W.; McArt, Darragh G.; Longley, Daniel B.

Response to Park et al. reply to Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study'

HISTOPATHOLOGY

IF4.1

2017-05-19

OAAI

Hynes, Sean O.; Coleman, Helen G.; Kelly, Paul J.; Dunne, Philip D.; Salto-Tellez, Manuel; Loughrey, Maurice B.

研究方向