Clare M. Isacke - Publications, H-index & Citations

Clare M. Isacke

the institute of cancer research

63H指数

472论文数

1.1W被引数

收录论文 111

发表时间

A disease model resource reveals core principles of tissue-specific cancer evolution 一个疾病模型资源揭示了组织特异性癌症演化的核心原则

Nature

IF48.5

2026-02-25

OAAI

Sebastian Mueller; Niklas de Andrade Krätzig; Markus Tschurtschenthaler; Miguel G. Silva; Chiara Thordsen; Riccardo Trozzo; Perrine Simon; Frederic Saab; Thorsten Kaltenbacher; Magdalena Zukowska; Daniele Lucarelli; Rupert Öllinger; Joscha Griger; Nina Groß; Tanja Groll; Jessica Löprich; Antonio E. Zaurito; Linus R. Schömig; Jeroen M. Bugter; Stefanie Bärthel; Chiara Falcomatà; Alexander Strong; Cordelia Brandt; Mulham Najajreh; Aristeidis Papargyriou; Roman Maresch; Katharina A. N. Collins; David Sailer; Christian Schneeweis; Sebastian Burger; Lisa M. Fröhlich; Christine Klement; Alexander Belka; Juan J. Montero; Ute Jungwirth; Maximilian Reichert; Markus Moser; Jens Neumann; George Vassiliou; Juan Cadiñanos; Ignacio Varela; Carsten Marr; Daniel F. Alonso; Pier-Luigi Lollini; Jean Zhao; Louis Chesler; Clare M. Isacke; Angela Riedel; Christian J. Braun; Martin L. Sos; Filippo Beleggia; Hans C. Reinhardt; Monica Musteanu; Mariano Barbacid; Michael Quante; Marc Schmidt-Supprian; Günter Schneider; Simon Clare; Trevor D. Lawley; Gordon Dougan; Katja Steiger; Nathalie Conte; Allan Bradley; Lena Rad; Dieter Saur; Roland Rad

Clinical challenges and proposed solutions for patients with invasive lobular breast cancer 浸润性小叶乳腺癌患者的临床挑战和建议的解决方案

Annals of Oncology

IF65.4

2025-07-21

OAAI

K. Van Baelen; E. Sawyer; J. Van Cauwenberge; P. Aftimos; M.F. Covington; M. Maetens; G. Zels; C. Brisken; L. Djerroudi; R. Dresen; A. Fitzpatrick; R.L. Flaherty; G. Floris; S. Freeney; A.B. Hanker; D. Honey; C.M. Isacke; R.C. Jankowitz; R. Jeselsohn; T. Koorman; C. Kuhl; S. Linn; C.J. Lord; C. Malhaire; J. Mouabbi; R. Mukhtar; G. Nader-Marta; R. Natrajan; P. Neven; S. Oesterreich; J.L. Sandoval; S.J. Schnitt; E. Senkus; C. Turner; V. Vandecaveye; H. Wildiers; A. Vincent-Salomon; P.W.B. Derksen; C. Desmedt

Essential requirements for reporting radiation therapy in breast cancer clinical trials: An international multi-disciplinary consensus endorsed by the European Society for Radiotherapy and Oncology (ESTRO)

RADIOTHERAPY AND ONCOLOGY

IF5.3

2024-06-01

OAAI

Kaidar-Person, Orit; Meattini, Icro; Boersma, Liesbeth J.; Becherini, Carlotta; Cortes, Javier; Curigliano, Giuseppe; de Azambuja, Evandro; Harbeck, Nadia; Rugo, Hope S.; Del Mastro, Lucia; Gennari, Alessandra; Isacke, Clare M.; Maraldo, Maja Vestm o; Marangoni, Elisabetta; Marta, Gustavo Nader; Mjaaland, Ingvil; Salvestrini, Viola; Spanic, Tanja; Visani, Luca; Morandi, Andrea; Lambertini, Matteo; Livi, Lorenzo; Coles, Charlotte E.; Poortmans, Philip; V. Offersen, Birgitte

Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer 基于通路的签名可预测浸润性小叶乳腺癌的患者结局，化疗益处和合成致死依赖性

BRITISH JOURNAL OF CANCER

IF6.8

2024-04-10

OAAI

Alexander, John; Schipper, Koen; Nash, Sarah; Brough, Rachel; Kemp, Harriet; Iacovacci, Jacopo; Isacke, Clare; Natrajan, Rachael; Sawyer, Elinor; Lord, Christopher J.; Haider, Syed

Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2024-02-27

OAAI

Ash, Sarah L.; Orha, Rebecca; Mole, Holly; Dinesh-Kumar, Meg; Lee, Steven P.; Turrell, Frances K.; Isacke, Clare M.

Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers

CANCER RESEARCH

IF16.6

2023-10-06

OAAI

Soosainathan, Arany; Iravani, Marjan; El-Botty, Rania; Alexander, John; Sourd, Laura; Morisset, Ludivine; Painsec, Pierre; Orha, Rebecca; Nikitorowicz-Buniak, Joanna; Pancholi, Sunil; Haider, Syed; Dowsett, Mitch; Marangoni, Elisabetta; Martin, Lesley-Ann; Isacke, Clare M.

Safety profile of cyclin-dependent kinase (CDK) 4/6 inhibitors with concurrent radiation therapy: A systematic review and meta-analysis

CANCER TREATMENT REVIEWS

IF10.5

2023-09-01

OAAI

Becherini, Carlotta; Visani, Luca; Caini, Saverio; Bhattacharya, Indrani S.; Kirby, Anna M.; Marta, Gustavo Nader; Morgan, Gilberto; Salvestrini, Viola; Coles, Charlotte E.; Cortes, Javier; Curigliano, Giuseppe; de Azambuja, Evandro; Harbeck, Nadia; Isacke, Clare M.; Kaidar-Person, Orit; Marangoni, Elisabetta; Offersen, Birgitte; Rugo, Hope S.; Morandi, Andrea; Lambertini, Matteo; Poortmans, Philip; Livi, Lorenzo; Meattini, Icro

Safety profile of trastuzumab-emtansine (T-DM1) with concurrent radiation therapy: A systematic review and meta-analysis

RADIOTHERAPY AND ONCOLOGY

IF5.3

2023-09-01

OAAI

Salvestrini, Viola; Kim, Kyubo; Caini, Saverio; Alkner, Sara; Ekholm, Maria; Skytta, Tanja; Becherini, Carlotta; Coles, Charlotte E.; Kaidar-Person, Orit; Offersen, Birgitte; Visani, Evandro de Azambuja Luca; Visani, Luca; Cortes, Javier; Harbeck, Nadia; Rugo, Hope S.; Isacke, Clare M.; Marangoni, Elisabetta; Morandi, Andrea; Lambertini, Matteo; Poortmans, Philip; Livi, Lorenzo; Meattini, Icro

Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse

NATURE CANCER

IF28.5

2023-03-13

OAAI

Turrell, Frances K.; Orha, Rebecca; Guppy, Naomi J.; Gillespie, Andrea; Guelbert, Matthew; Starling, Chris; Haider, Syed; Isacke, Clare M.

Endo180 (MRC2) Antibody-Drug Conjugate for the Treatment of Sarcoma

MOLECULAR CANCER THERAPEUTICS

IF5.5

2022-11-18

OAAI

Evans, Rachel J.; Perkins, Douglas W.; Selfe, Joanna; Kelsey, Anna; Birch, Gavin P.; Shipley, Janet M.; Schipper, Koen; Isacke, Clare M.

Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment (vol 132, e148667, 2022)

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-10-03

OAAI

Araujo, Angela M.; Abaurrea, Andrea; Azcoaga, Peio; Lopez-Velazco, Joanna I.; Manzano, Sara; Rodriguez, Javier; Rezola, Ricardo; Egia-Mendikute, Leire; Valdes-Mora, Fatima; Flores, Juana M.; Jenkins, Liam; Pulido, Laura; Osorio-Querejeta, Inaki; Fernandez-Nogueira, Patricia; Ferrari, Nicola; Viera, Cristina; Martin-Martin, Natalia; Tzankov, Alexandar; Eppenberger-Castori, Serenella; Alvarez-Lopez, Isabel; Urruticoechea, Ander; Bragado, Paloma; Coleman, Nicholas; Palazon, Asis; Carracedo, Arkaitz; Gallego-Ortega, David; Calvo, Fernando; Isacke, Clare M.; Caffarel, Maria M.; Lawrie, Charles H.

Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade 癌症相关成纤维细胞抑制CD8 T细胞浸润并赋予对免疫检查点阻断的抗性

CANCER RESEARCH

IF16.6

2022-06-24

104

OAAI

Jenkins, Liam; Jungwirth, Ute; Avgustinova, Alexandra; Iravani, Marjan; Mills, Adam; Haider, Syed; Harper, James; Isacke, Clare M.

Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer (vol 41, pg 2932, 2022)

ONCOGENE

IF7.3

2022-05-24

OAAI

Ratze, Max A. K.; Koorman, Thijs; Sijnesael, Thijmen; Bassey-Archibong, Blessing; van de Ven, Robert; Enserink, Lotte; Visser, Daan; Jaksani, Sridevi; Viciano, Ignacio; Bakker, Elvira R. M.; Richard, Francois; Tutt, Andrew; O'Leary, Lynda; Fitzpatrick, Amanda; Roca-Cusachs, Pere; van Diest, Paul J.; Desmedt, Christine; Daniel, Juliet M.; Isacke, Clare M.; Derksen, Patrick W. B.

Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer

ONCOGENE

IF7.3

2022-04-18

OAAI

Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment 基质制瘤素M细胞因子通过重编程肿瘤微环境促进乳腺癌进展

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-04-01

OAAI

Araujo, Angela M.; Abaurrea, Andrea; Azcoaga, Peio; Lopez-Velazco, Joanna, I; Manzano, Sara; Rodriguez, Javier; Rezola, Ricardo; Egia-Mendikute, Leire; Valdes-Mora, Fatima; Flores, Juana M.; Jenkins, Liam; Pulido, Laura; Osorio-Querejeta, Inaki; Fernandez-Nogueira, Patricia; Ferrari, Nicola; Viera, Cristina; Martin-Martin, Natalia; Tzankov, Alexandar; Eppenberger-Castori, Serenella; Alvarez-Lopez, Isabel; Urruticoechea, Ander; Bragado, Paloma; Coleman, Nicholas; Palazon, Asis; Carracedo, Arkaitz; Gallego-Ortega, David; Calvo, Fernando; Isacke, Clare M.; Caffarel, Maria M.; Lawrie, Charles H.

Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis

CLINICAL CANCER RESEARCH

IF10.2

2022-03-14

OAAI

Fitzpatrick, Amanda; Iravani, Marjan; Mills, Adam; Childs, Lucy; Alaguthurai, Thanussuyah; Clifford, Angela; Garcia-Murillas, Isaac; Van Laere, Steven; Dirix, Luc; Harries, Mark; Okines, Alicia; Turner, Nicholas C.; Haider, Syed; Tutt, Andrew N. J.; Isacke, Clare M.

Exploiting novel models of endocrine-resistant breast cancer to identify new therapeutic targets

CANCER RESEARCH

IF16.6

2022-02-15

PREAI

Soosainathan, Arany; Nikitorowicz-Buniak, Joanna; Pancholi, Sunil; Iravani, Marjan; Alexander, John; Haider, Syed; Johnston, Stephen R.; Dowsett, Mitchell; Martin, Lesley A.; Isacke, Clare M.

Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis

NATURE COMMUNICATIONS

IF15.7

2021-06-10

OAAI

Jungwirth, Ute; van Weverwijk, Antoinette; Evans, Rachel J.; Jenkins, Liam; Vicente, David; Alexander, John; Gao, Qiong; Haider, Syed; Iravani, Marjan; Isacke, Clare M.

The INTEND 1 randomized controlled trial of duct endoscopy as an indicator of margin excision in breast conservation surgery

BREAST CANCER RESEARCH AND TREATMENT

IF3

2021-01-04

PREAI

Gui, Gerald; Panopoulou, Effrosyni; Tang, Sarah; Twelves, Dominique; Kabir, Mohammed; Ward, Ann; Montgomery, Catherine; Nerurkar, Ashutosh; Osin, Peter; Isacke, Clare M.

Assessing tumour fraction of CSF cfDNA improves diagnostic accuracy and therapeutic monitoring in breast cancer leptomeningeal metastasis (BCLM)

ANNALS OF ONCOLOGY

IF65.4

2020-09-01

OAAI

Fitzpatrick, A.; Iravani, M.; Okines, A.; Harries, M.; Tutt, A.; Isacke, C.

研究方向