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K

Kie Kyon Huang

Duke-NUS Medical School
H指数:21
被引数:2,444

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Single-cell pharmacogenomic landscapes of epigenetic therapy revealed by gastric cancer Perturb-seq

通过胃癌Perturb-seq揭示的表观遗传疗法的单细胞药物基因组景观

Nature Communications
IF15.7
2026-11-020
OAAI
Chang Xu; Haoran Ma; Taotao Sheng; Ming Hui Lee; Siti Aishah Binte Abdul Ghani; Shen Kiat Lim; Laura Perlaza-Jimenez; Kie Kyon Huang; Supriya Srivastava; Xuewen Ong; Su Ting Tay; Shamaine Wei Ting Ho; Zhi Xuan Ong; Angie Lay Keng Tan; Feng Zhu; Hassan Ashktorab; Alfred Sze-Lok Cheng; Anand D. Jeyasekharan; Shang Li; Ming Teh; Raghav Sundar; David R. Powell; Joseph Rosenbluh; Wei Peng Yong; Jimmy Bok-Yan So; Patrick Tan
Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases

胃癌腹膜转移的空间分辨生态位和肿瘤微环境变化

GASTROENTEROLOGY
IF25.1
2024-12-011
OA
Zhao, Joseph J.; Ong, Chin-Ann Johnny; Srivastava, Supriya; Chia, Daryl Kai Ann; Ma, Haoran; Huang, Kiekyon; Sheng, Taotao; Ramnarayanan, Kalpana; Ong, Xuewen; Tay, Su Ting; Hagihara, Takeshi; Tan, Angie Lay Keng; Teo, Melissa Ching Ching; Tan, Qiu Xuan; Ng, Gillian; Tan, Joey Wee-Shan; Ng, Matthew Chau Hsien; Gwee, Yong Xiang; Walsh, Robert; Law, Jia Hao; Shabbir, Asim; Kim, Guowei; Tay, Yvonne; Her, Zhisheng; Leoncini, Giuseppe; Teh, Bin Tean; Hong, Jing Han; Tay, Ryan Yong Kiat; Teo, Chong Boon; Dings, Mark P. G.; Bijlsma, Maarten; Lum, Jeffrey Huey Yew; Mathur, Sachin; Pietrantonio, Filippo; Blum, Steven M.; van Laarhoven, Hanneke; Klempner, Samuel J.; Yong, Wei Peng; So, Jimmy Bok Yan; Chen, Qingfeng; Tan, Patrick; Sundar, Raghav
Phase I PIANO trialdPIPAC-oxaliplatin d PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes
ESMO OPEN
IF8.3
2024-09-011
OAAI
Sundar, R.; Chia, D. K. A.; Zhao, J. J.; Lee, A. R. Y. B.; Kim, G.; Tan, H. L.; Pang, A.; Shabbir, A.; Willaert, W.; Ma, H.; Huang, K. K.; Hagihara, T.; Tan, A. L. K.; Ong, C. -A. J.; Wong, J. S. M.; Seo, C. J.; Walsh, R.; Chan, G.; Cheo, S. W.; Soh, C. C. C.; Callebout, E.; Geboes, K.; Ng, M. C. H.; Lum, J. H. Y.; Leow, W. Q.; Selvarajan, S.; Hoorens, A.; Ang, W. H.; Pang, H.; Tan, P.; Yong, W. P.; Chia, C. S. L.; Ceelen, W.; So, J. B. Y.
Comprehensive Molecular Phenotyping of ARID1A-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic Opportunities
CANCER RESEARCH
IF16.6
2024-04-150
PRE
Xu, Chang; Huang, Kie Kyon; Law, Jia Hao; Chua, Joy Shijia; Sheng, Taotao; Flores, Natasha M.; Pizzi, Melissa Pool; Okabe, Atsushi; Tan, Angie Lay Keng; Zhu, Feng; Kumar, Vikrant; Lu, Xiaoyin; Benitez, Ana Morales; Lian, Benedict Shi Xiang; Ma, Haoran; Ho, Shamaine Wei Ting; Ramnarayanan, Kalpana; Anene-Nzelu, Chukwuemeka George; Razavi-Mohseni, Milad; Ghani, Siti Aishah Binte Abdul; Tay, Su Ting; Ong, Xuewen; Lee, Ming Hui
Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric neoplasia using the longitudinally monitored cohorts
EBIOMEDICINE
IF10.8
2023-12-017
OAAI
Usui, Genki; Matsusaka, Keisuke; Huang, Kie Kyon; Zhu, Feng; Shinozaki, Tomohiro; Fukuyo, Masaki; Rahmutulla, Bahityar; Yogi, Norikazu; Okada, Tomoka; Minami, Mizuki; Seki, Motoaki; Sakai, Eiji; Fujibayashi, Kazutoshi; Tsao, Stephen Kin Kwok; Khor, Christopher; Ang, Tiing Leong; Abe, Hiroyuki; Matsubara, Hisahiro; Fukayama, Masashi; Gunji, Toshiaki; Matsuhashi, Nobuyuki; Morikawa, Teppei; Ushiku, Tetsuo; Yeoh, Khay Guan; Tan, Patrick; Kaneda, Atsushi
Integrated environmental, lifestyle, and epigenetic risk prediction of primary gastric cancer
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Usui, Genki; Matsusaka, Keisuke; Huang, Kie K.; Zhu, Feng; Shinozaki, Tomohiro; Fukuyo, Masaki; Rahmutulla, Bahityar; Yogi, Norikazu; Okada, Tomoka; Seki, Motoaki; Sakai, Eiji; Fujibayashi, Kazutoshi; Tsao, Stephen K.; Khor, Christopher; Ang, Tiing L.; Abe, Hiroyuki; Matsubara, Hisahiro; Fukayama, Masashi; Gunji, Toshiaki; Matsuhashi, Nobuyuki; Morikawa, Teppei; Ushiku, Tetsuo; Yeoh, Khay G.; Tan, Patrick; Kaneda, Atsushi
Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer (vol 82, pg 2538, 2022)
CANCER RESEARCH
IF16.6
2023-03-020
OA
Nargund, Amrita M.; Xu, Chang; Mandoli, Amit; Okabe, Atsushi; Bin Chen, Gao; Huang, Kie Kyon; Sheng, Taotao; Yao, Xiaosai; Teo, Jia Ming Nickolas; Sundar, Raghav; Kok, Yee Jiun; See, Yi Xiang; Xing, Manjie; Li, Zhimei; Yong, Chern Han; Anand, Aparna; Isa, Zul Fazreen Bin Adam; Poon, Lai Fong; Ng, Michelle Shu Wen; Koh, Javier Yu Peng; Ooi, Wen Fong; Tay, Su Ting; Ong, Xuewen; Tan, Angie Lay Keng; Smoot, Duane T.; Ashktorab, Hassan; Grabsch, Heike I.; Fullwood, Melissa J.; Teh, Bin Tean; Bi, Xuezhi; Kaneda, Atsushi; Li, Shang; Tan, Patrick
Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer
CANCER RESEARCH
IF16.6
2022-05-1812
OA
Nargund, Amrita M.; Xu, Chang; Mandoli, Amit; Okabe, Atsushi; Bin Chen, Gao; Huang, Kie Kyon; Sheng, Taotao; Yao, Xiaosai; Teo, Jia Ming Nickolas; Sundar, Raghav; Kok, Yee Jiun; See, Yi Xiang; Xing, Manjie; Li, Zhimei; Yong, Chern Han; Anand, Aparna; Fazreen, A. I. Zul; Poon, Lai Fong; Ng, Michelle Shu Wen; Koh, Javier Yu Peng; Ooi, Wen Fong; Tay, Su Ting; Ong, Xuewen; Tan, Angie Lay Keng; Grabsch, Heike, I; Fullwood, Melissa J.; Teh, Tean Bin; Bi, Xuezhi; Kaneda, Atsushi; Li, Shang; Tan, Patrick
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer

整合表观基因组学和高通量功能增强子谱分析揭示胃癌中增强子异质性的决定因素

GENOME MEDICINE
IF11.2
2021-10-1113
OAAI
Sheng, Taotao; Ho, Shamaine Wei Ting; Ooi, Wen Fong; Xu, Chang; Xing, Manjie; Padmanabhan, Nisha; Huang, Kie Kyon; Ma, Lijia; Ray, Mohana; Guo, Yu Amanda; Sim, Ngak Leng; Anene-Nzelu, Chukwuemeka George; Chang, Mei Mei; Razavi-Mohseni, Milad; Beer, Michael A.; Foo, Roger Sik Yin; Sundar, Raghav; Chan, Yiong Huak; Tan, Angie Lay Keng; Ong, Xuewen; Skanderup, Anders Jacobsen; White, Kevin P.; Jha, Sudhakar; Tan, Patrick
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation
GENOME BIOLOGY
IF9.4
2021-06-0114
OAAI
Padmanabhan, Nisha; Kyon, Huang Kie; Boot, Arnoud; Lim, Kevin; Srivastava, Supriya; Chen, Shuwen; Wu, Zhiyuan; Lee, Hyung-O K.; Mukundan, Vineeth T.; Chan, Charlene; Chan, Yarn Kit; Xuewen, Ong; Pitt, Jason J.; Isa, Zul Fazreen Adam; Xing, Manjie; Lee, Ming Hui; Tan, Angie Lay Keng; Ting, Shamaine Ho Wei; Luftig, Micah A.; Kappei, Dennis; Kruger, Warren D.; Bian, Jinsong; Ho, Ying Swan; Teh, Ming; Rozen, Steve George; Tan, Patrick
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-05-0415
OA
Xing, Manjie; Ooi, Wen Fong; Tan, Jing; Qamra, Aditi; Lee, Po-Hsien; Li, Zhimei; Xu, Chang; Padmanabhan, Nisha; Lim, Jing Quan; Guo, Yu Amanda; Yao, Xiaosai; Amit, Mandoli; Ng, Ley Moy; Sheng, Taotao; Wang, Jing; Huang, Kie Kyon; Anene-Nzelu, Chukwuemeka George; Ho, Shamaine Wei Ting; Ray, Mohana; Ma, Lijia; Fazzi, Gregorio; Lim, Kevin Junliang; Wijaya, Giovani Claresta; Zhang, Shenli; Nandi, Tannistha; Yan, Tingdong; Chang, Mei Mei; Das, Kakoli; Isa, Zul Fazreen Adam; Wu, Jeanie; Poon, Polly Suk Yean; Lam, Yue Ning; Lin, Joyce Suling; Tay, Su Ting; Lee, Ming Hui; Tan, Angie Lay Keng; Ong, Xuewen; White, Kevin; Rozen, Steven George; Beer, Michael; Foo, Roger Sik Yin; Grabsch, Heike Irmgard; Skanderup, Anders Jacobsen; Li, Shang; Teh, Bin Tean; Tan, Patrick

研究方向

暂未获取到该数据
P
Patrick Tan
H 指数:108论文数:1,022被引数:4.7万
S
Su Ting Tay
H 指数:24论文数:109被引数:2,979
R
Raghav Sundar
H 指数:42论文数:382被引数:6,519
A
Angie Lay Keng Tan
H 指数:18论文数:107被引数:1,602
X
Xuewen Ong
H 指数:17论文数:115被引数:852
B
Bin Tean Teh
H 指数:113论文数:1,105被引数:5.3万
J
Jimmy Bok Yan So
H 指数:59论文数:571被引数:1.3万
M
Manjie Xing
H 指数:17论文数:71被引数:2,147
W
Wei Peng Yong
H 指数:58论文数:507被引数:1.5万
A
Atsushi Okabe
H 指数:19论文数:108被引数:1,268