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S

Stephen-John Sammut

Institute of Cancer Research
H指数:28
被引数:7,936

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Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells

通过整合免疫细胞、基质细胞和肿瘤细胞的去卷积表达模式，增强对乳腺癌患者化疗反应的预测

Cancer Letters
IF10.1
2025-10-300
PRE
Saugato Rahman Dhruba; Sahil Sahni; Binbin Wang; Di Wu; Padma Sheila Rajagopal; Yael Schmidt; Eldad D. Shulman; Sanju Sinha; Stephen-John Sammut; Carlos Caldas; Kun Wang; Eytan Ruppin
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition

肿瘤相关中性粒细胞前体损害同源DNA修复并促进对PARP抑制的敏感性

Nature Communications
IF15.7
2025-07-300
OA
Siddhartha Mukherjee; Cindy Garda; Letizia Boffa; Angela Rita Elia; Matteo Massara; Maria Teresa Balia; Daniela Brina; Simone Mosole; Anna Campagnari; Giada Andrea Cassanmagnago; Andrea Rinaldi; Giacomo Lazzaroni; David Jarrossay; Diego Morone; Ilaria Ceppi; Riccardo De Sillo; Isabella Giacomini; Ilaria Craparotta; Laura Di Rito; Simon Barry; Endre Laczko; Sebastian Streb; Francesco Meani; Simona Di Lascio; Nancy Hynes; Enrico Lugli; Simone Puccio; Stephen-John Sammut; Ulrike Perriard; Yves Harder; Lorenzo Rossi; Maria Luisa Gasparri; Marco Bolis; Petr Cejka; Arianna Calcinotto
Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones

人类乳腺癌单细胞来源克隆的适应性及转录组可塑性

CELL REPORTS
IF6.9
2025-05-010
OA
Nguyen, Long V.; Eyal-Lubling, Yaniv; Guerrero-Romero, Daniel; Kronheim, Sarah; Chin, Suet-Feung; Garcia, Raquel Manzano; Sammut, Stephen-John; Lerda, Giulia; Lui, Allan J. W.; Bardwell, Helen A.; Greenwood, Wendy; Shin, Hee Jin; Masina, Riccardo; Kania, Katarzyna; Bruna, Alejandra; Esmaeilishirazifard, Elham; Kolyvas, Emily A.; Aparicio, Samuel; Rueda, Oscar M.; Caldas, Carlos
A large-scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression-free survival

一项针对转移性乳腺癌患者的大规模回顾性研究，采用循环肿瘤DNA和机器学习方法来预测治疗效果和无进展生存期。

MOLECULAR ONCOLOGY
IF4.5
2025-04-150
OAAI
Emma J. Beddowes; Mario Ortega Duran; Solon Karapanagiotis; Alistair Martin; Meiling Gao; Riccardo Masina; Ramona Woitek; James Tanner; Fleur Tippin; Justine Kane; Jonathan Lay; Anja Brouwer; Stephen-John Sammut; Suet-Feung Chin; Davina Gale; Dana W. Y. Tsui; Sarah-Jane Dawson; Nitzan Rosenfeld; Maurizio Callari; Oscar M. Rueda; Carlos Caldas
A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer
NPJ BREAST CANCER
IF7.6
2025-02-130
OA
Mukhtar, Rita A.; Gottipati, Soumya; Yau, Christina; Lopez-Tarruella, Sara; Earl, Helena; Hayward, Larry; Hiller, Louise; Osdoit, Marie; van der Noordaa, Marieke; de Croze, Diane; Hamy, Anne-Sophie; Lae, Marick; Reyal, Fabien; Sonke, Gabe S.; Steenbruggen, Tessa G.; van Seijen, Maartje; Wesseling, Jelle; Martin, Miguel; del Monte-Millan, Maria; Boughey, Judy C.; Goetz, Matthew P.; Hoskin, Tanya; Valero, Vicente; Edge, Stephen B.; Abraham, Jean E.; Bartlett, John M. S.; Caldas, Carlos; Dunn, Janet; Provenzano, Elena; Sammut, Stephen-John; Thomas, Jeremy S.; Graham, Ashley; Hall, Peter; Mackintosh, Lorna; Fan, Fang; Godwin, Andrew K.; Schwensen, Kelsey; Sharma, Priyanka; Demichele, Angela M.; Cole, Kimberly; Pusztai, Lajos; Kim, Mi-Ok; van 't Veer, Laura; Cameron, David; Esserman, Laura J.; Fraser Symmans, W.
Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation

使用基于深度学习的语义分割从乳腺癌的CD-31免疫组织化学图像量化肿瘤脉管系统环境

BREAST CANCER RESEARCH
IF5.6
2025-02-040
OAAI
Whitmarsh, Tristan; Cope, Wei; Carmona-Bozo, Julia; Manavaki, Roido; Sammut, Stephen-John; Woitek, Ramona; Provenzano, Elena; Brown, Emma L.; Bohndiek, Sarah E.; Gallagher, Ferdia A.; Caldas, Carlos; Gilbert, Fiona J.; Markowetz, Florian
A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics

一种深度学习框架，通过转录组学预测组织病理学图像的癌症治疗反应

NATURE CANCER
IF28.5
2024-07-035
OA
Hoang, Danh-Tai; Dinstag, Gal; Shulman, Eldad D.; Hermida, Leandro C.; Ben-Zvi, Doreen S.; Elis, Efrat; Caley, Katherine; Sammut, Stephen-John; Sinha, Sanju; Sinha, Neelam; Dampier, Christopher H.; Stossel, Chani; Patil, Tejas; Rajan, Arun; Lassoued, Wiem; Strauss, Julius; Bailey, Shania; Allen, Clint; Redman, Jason; Beker, Tuvik; Jiang, Peng; Golan, Talia; Wilkinson, Scott; Sowalsky, Adam G.; Pine, Sharon R.; Caldas, Carlos; Gulley, James L.; Aldape, Kenneth; Aharonov, Ranit; Stone, Eric A.; Ruppin, Eytan
Comparison of tumor-informed and tumor-naive sequencing assays for ctDNA detection in breast cancer

用于乳腺癌中ctDNA检测的肿瘤知情和未肿瘤测序分析的比较

EMBO MOLECULAR MEDICINE
IF8.3
2023-05-109
OAAI
Santonja, Angela; Cooper, Wendy N.; Eldridge, Matthew D.; Edwards, Paul A. W.; Morris, James A.; Edwards, Abigail R.; Zhao, Hui; Heider, Katrin; Couturier, Dominique-Laurent; Vijayaraghavan, Aadhitthya; Mennea, Paulius; Ditter, Emma-Jane; Smith, Christopher G.; Boursnell, Chris; Garcia, Raquel Manzano; Rueda, Oscar M.; Beddowes, Emma; Biggs, Heather; Sammut, Stephen-John; Rosenfeld, Nitzan; Caldas, Carlos; Abraham, Jean E.; Gale, Davina
AACR Project GENIE: 100,000 Cases and Beyond

AACR项目精灵: 100,000个案例及以后

CANCER DISCOVERY
IF33.3
2022-07-1239
OAAI
Pugh, Trevor J.; Bell, Jonathan L.; Bruce, Jeff P.; Doherty, Gary J.; Galvin, Matthew; Green, Michelle F.; Hunter-Zinck, Haley; Kumari, Priti; Lenoue-Newton, Michele L.; Li, Marilyn M.; Lindsay, James; Mazor, Tali; Ovalle, Andrea; Sammut, Stephen-John; Schultz, Nikolaus; Yu, Thomas, V; Sweeney, Shawn M.; Bernard, Brady
Multi-omic machine learning predictor of breast cancer therapy response

乳腺癌治疗反应的多组学机器学习预测器

Nature
IF48.5
2021-12-070
OAAI
Stephen-John Sammut; Mireia Crispin-Ortuzar; Suet-Feung Chin; Elena Provenzano; Helen A. Bardwell; Wenxin Ma; Wei Cope; Ali Dariush; Sarah-Jane Dawson; Jean E. Abraham; Janet Dunn; Louise Hiller; Jeremy Thomas; David A. Cameron; John M. S. Bartlett; Larry Hayward; Paul D. Pharoah; Florian Markowetz; Oscar M. Rueda; Helena M. Earl; Carlos Caldas
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

1538乳腺癌的DNA甲基化景观揭示了与复制相关的时钟，表观基因组不稳定性和顺式调节

NATURE COMMUNICATIONS
IF15.7
2021-09-1332
OAAI
Batra, Rajbir Nath; Lifshitz, Aviezer; Vidakovic, Ana Tufegdzic; Chin, Suet-Feung; Sati-Batra, Ankita; Sammut, Stephen-John; Provenzano, Elena; Ali, H. Raza; Dariush, Ali; Bruna, Alejandra; Murphy, Leigh; Purushotham, Arnie; Ellis, Ian; Green, Andrew; Garrett-Bakelman, Francine E.; Mason, Chris; Melnick, Ari; Aparicio, Samuel A. J. R.; Rueda, Oscar M.; Tanay, Amos; Caldas, Carlos
The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers

HER2-negative原发性乳腺癌的时间突变和免疫肿瘤微环境重塑

NPJ BREAST CANCER
IF7.6
2021-06-075
OAAI
De Mattos-Arruda, Leticia; Cortes, Javier; Blanco-Heredia, Juan; Tiezzi, Daniel G.; Villacampa, Guillermo; Goncalves-Ribeiro, Samuel; Pare, Laia; Souza, Carla Anjos; Ortega, Vanesa; Sammut, Stephen-John; Cusco, Pol; Fasani, Roberta; Chin, Suet-Feung; Perez-Garcia, Jose; Dienstmann, Rodrigo; Nuciforo, Paolo; Villagrasa, Patricia; Rubio, Isabel T.; Prat, Aleix; Caldas, Carlos
Residual cancer burden after neoadjuvant therapy and long-term survival outcomes in breast cancer: A multi-center pooled analysis
CANCER RESEARCH
IF16.6
2020-02-1513
PRE
Yau, Christina; van der Noordaa, Marieke; Wei, Jane; Osdoit, Marie; Reyal, Fabien; Hamy, Anne-Sophie; Lae, Marick; Martin, Miguel; del Monte, Maria; Boughey, Judy C.; Gould, Rebekah; Wesseling, Jelle; Steenbruggen, Tessa; van Seijen, Maartje; Sonke, Gabe; Edge, Stephen; Sammut, Stephen-John; Provenzano, Elena; Abraham, Jean; Hall, Peter; Graham, Ashley; Mackintosh, Lorna; Cameron, David; Wang, Alice; Sharma, Priyanka; Cole, Kimberly; Pusztai, Lajos; Kim, Mi-Ok; van't Veer, Laura; Esserman, Laura; Symmans, W. Fraser

研究方向

暂未获取到该数据
C
Carlos Caldas
H 指数:158论文数:1,383被引数:12.8万
S
Suet‐Feung Chin
H 指数:76论文数:366被引数:4.7万
O
Oscar M. Rueda
H 指数:56论文数:339被引数:2.5万
E
Elena Provenzano
H 指数:76论文数:394被引数:3.8万
A
Alejandra Bruna
H 指数:41论文数:205被引数:8,900
S
Samuel Aparício
H 指数:115论文数:474被引数:8.5万
M
Maurizio Callari
H 指数:0论文数:2被引数:1
P
Paul D.P. Pharoah
H 指数:150论文数:1,771被引数:9.6万
A
Arnie Purushotham
H 指数:56论文数:369被引数:2.3万
I
Ian O. Ellis
H 指数:147论文数:1,774被引数:11.0万