Charles P. Theuer - Publications, H-index & Citations

Charles P. Theuer

Genentech

43H指数

276论文数

7.6K被引数

收录论文 47

发表时间

Quantifying Return on Investment of Differentiating Technologies in Drug Development: A Decision Analytics Framework 量化差异化技术在药物开发中投资回报的决策分析框架

Journal of Pharmaceutical Innovation

IF2.7

2026-04-23

OAAI

Ryan P. Nolan; Charles Theuer

Anti-Endoglin monoclonal antibody prevents the progression of liver sinusoidal endothelial inflammation and fibrosis in MASH 抗Endoglin单克隆抗体预防MASH中肝窦内皮炎症和纤维化的进展

LIFE SCIENCES

IF5.1

2025-03-01

OAAI

Eissazadeh, Samira; Fikrova, Petra; Rathouska, Jana Urbankova; Nemeckova, Ivana; Tripska, Katarina; Vasinova, Martina; Havelek, Radim; Mohammadi, Seyedehniloufar; Sa, Ivone Cristina Igreja; Theuer, Charles; Konig, Matthias; Micuda, Stanislav; Nachtigal, Petr

Endoglin inhibitor TRC105 with or without bevacizumab for bevacizumab-refractory glioblastoma (ENDOT): a multicenter phase II trial

COMMUNICATIONS MEDICINE

IF6.3

2023-09-08

OAAI

Ahluwalia, Manmeet S.; Rogers, Lisa R.; Chaudhary, Rekha; Newton, Herbert; Ozair, Ahmad; Khosla, Atulya A.; Nixon, Andrew B.; Adams, Bonne J.; Seon, Ben K.; Peereboom, David M.; Theuer, Charles P.

A phase I/II study of preoperative letrozole, everolimus, and carotuximab in stage 2 and 3 hormone receptor-positive and Her2-negative breast cancer

BREAST CANCER RESEARCH AND TREATMENT

IF3

2023-02-03

OAAI

Vaklavas, Christos; Stringer-Reasor, Erica M.; Elkhanany, Ahmed M.; Ryan, Kevin J.; Li, Yufeng; Theuer, Charles P.; Acosta, Edward P.; Wei, Shi; Yang, Eddy S. S.; Grizzle, William E.; Forero-Torres, Andres

Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells

FRONTIERS IN MEDICINE

IF3

2022-09-07

OAAI

Tripska, Katarina; Sa, Ivone Cristina Igreja; Vasinova, Martina; Vicen, Matej; Havelek, Radim; Eissazadeh, Samira; Svobodova, Zuzana; Vitverova, Barbora; Theuer, Charles; Bernabeu, Carmelo; Nachtigal, Petr

Identification of neuroblastoma cell lines with uncommon TAZ+/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-01-15

OAAI

Canzonetta, Claudia; Pelosi, Andrea; Di Matteo, Sabina; Veneziani, Irene; Tumino, Nicola; Vacca, Paola; Munari, Enrico; Pezzullo, Marco; Theuer, Charles; De Vito, Rita; Pistoia, Vito; Tomao, Luigi; Locatelli, Franco; Moretta, Lorenzo; Caruana, Ignazio; Azzarone, Bruno

Therapeutic effect of TRC105 and decitabine combination in AML xenografts

HELIYON

IF3.6

2020-10-01

OAAI

Baik, June; Felices, Martin; Yingst, Ashley; Theuer, Charles P.; Verneris, Michael R.; Miller, Jeffrey S.; Perlingeiro, Rita

Synergistic inhibition of cancer invasion and metastasis by combined anti-PD1-TRC105-mediated Endoglin targeting on cancer-associated fibroblasts and endothelial cells

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Schoonderwoerd, Mark J. A.; Paauwe, Madelon; Angela, Ricardo; Koops, Maaike; Harryvan, Tom; Sier, Cornelis; Fransen, Marieke; Theuer, Charles; Hawinkels, Lukas J. A. C.

An adaptive population enrichment phase III trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma (TAPPAS trial)TRC105和帕唑帕尼与单独帕唑帕尼在晚期血管肉瘤患者中的适应性群体富集III期试验 (TAPPAS试验)

ANNALS OF ONCOLOGY

IF65.4

2019-01-01

OAAI

Mehta, C. R.; Liu, L.; Theuer, C.

Modulation of Circulating Protein Biomarkers in Cancer Patients Receiving Bevacizumab and the Anti-Endoglin Antibody, TRC105

MOLECULAR CANCER THERAPEUTICS

IF5.5

2018-10-01

OAAI

Liu, Yingmiao; Starr, Mark D.; Brady, John C.; Rushing, Christel; Pang, Herbert; Adams, Bonne; Alvarez, Delia; Theuer, Charles P.; Hurwitz, Herbert I.; Nixon, Andrew B.

In Vivo Tumor-Targeted Dual-Modality PET/Optical Imaging with a Yolk/Shell-Structured Silica Nanosystem

NANO-MICRO LETTERS

IF36.3

2018-07-16

OAAI

Shi, Sixiang; Chen, Feng; Goel, Shreya; Graves, Stephen A.; Luo, Haiming; Theuer, Charles P.; Engle, Jonathan W.; Cai, Weibo

Targeting angiogenesis for radioimmunotherapy with a 177Lu-labeled antibody

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2017-08-18

OAAI

Ehlerding, Emily B.; Lacognata, Saige; Jiang, Dawei; Ferreira, Carolina A.; Goel, Shreya; Hernandez, Reinier; Jeffery, Justin J.; Theuer, Charles P.; Cai, Weibo

Inhibition of NF-kB inducing kinase (NIK) selectively abrogates NIK and TRAF3 mutant multiple myeloma tumor growth

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Versele, Matthias; Janssen, Lut; Geerts, Tamara; Floren, Wim; Janssens, Boudewijn; Millar, Hillary; Jacoby, Edgar; Gross, Gerhard; Ligny, Yannick; Simonnet, Yvan; Amblard, Nathalie; Querolle, Olivier; Csoka, Imre; Poncelet, Virginie; Tronel, Virginie; Nocquet-Thibault, Sophie; Meerpoel, Lieven; Edwards, James; Salvati, Marc; Balasubramanian, Sriram; Lenox, Laurie; Theuer, Charles; Attar, Ricardo; Stansfield, Ian

ENDOGLIN AS AN IMPORTANT REGULATOR OF COLORECTAL CANCER INVASION AND METASTASIS

GASTROENTEROLOGY

IF25.1

2017-04-01

PREAI

Paauwe, Madelon; Schoonderwoerd, Mark; van Pelt, Gabi; Theuer, Charles; Verspaget, Hein W.; Hardwick, James; Sier, Cornelis F.; ten Dijke, Peter; Hawinkels, Lukas

TRAXAR study: a randomized phase 2 trial of axitinib and TRC105 versus axitinib alone in patients with advanced or metastatic renal cell carcinoma (mRCC)

ANNALS OF ONCOLOGY

IF65.4

2016-10-01

OAAI

Choueiri, T.; Agarwal, N.; Ho, T.; Pal, S. K.; Seon, B.; Jivani, M.; Adams, B.; Shazer, R.; Theuer, C.

A phase 1b dose-escalation study of TRC105 (endoglin antibody) in combination with axitinib in patients with metastatic renal cell carcinoma (mRCC)

ANNALS OF ONCOLOGY

IF65.4

2016-10-01

OAAI

Choueiri, T.; Michaelson, M. D.; Posadas, E.; Sonpavde, G.; McDermott, D.; Seon, B.; Jivani, M.; Shazer, R.; Adams, B.; Theuer, C.

Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing Mesoporous Silica Nanostructures for In Vivo Biodistribution and Tumor Targeting Studies

ADVANCED SCIENCE

IF14.1

2016-05-27

OAAI

Goel, Shreya; Chen, Feng; Luan, Shijie; Valdovinos, Hector F.; Shi, Sixiang; Graves, Stephen A.; Ai, Fanrong; Barnhart, Todd E.; Theuer, Charles P.; Cai, Weibo

Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer

ONCOGENE

IF7.3

2016-01-25

OAAI

Paauwe, M.; Heijkants, R. C.; Oudt, C. H.; van Pelt, G. W.; Cui, C.; Theuer, C. P.; Hardwick, J. C. H.; Sier, C. F. M.; Hawinkels, L. J. A. C.

High Yield Production and Radiochemical Isolation of Isotopically Pure Arsenic-72 and Novel Radioarsenic Labeling Strategies for the Development of Theranostic Radiopharmaceuticals

BIOCONJUGATE CHEMISTRY

IF3.9

2015-12-22

OAAI

Ellison, Paul A.; Barnhart, Todd E.; Chen, Feng; Hong, Hao; Zhang, Yin; Theuer, Charles P.; Cai, Weibo; Nickles, Robert J.; DeJesus, Onofre T.

Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-09-28

OAAI

Luo, Haiming; Hernandez, Reinier; Hong, Hao; Graves, Stephen A.; Yang, Yunan; England, Christopher G.; Theuer, Charles P.; Nickles, Robert J.; Cai, Weibo

研究方向