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Targeting transcription factors through an IMiD independent zinc finger domain 通过IMiD非依赖性锌指域靶向转录因子 Liu, Bee Hui; Liu, Miao; Radhakrishnan, Sridhar; Dai, Meng-Yuan; Jaladanki, Chaitanya Kumar; Gao, Chong; Tang, Jing Ping; Kumari, Kalpana; Go, Mei Lin; Vu, Kim Anh L.; Kwon, Junsu; Seo, Hyuk-Soo; Song, Kijun; Tian, Xi; Feng, Li; Tan, Justin L.; Melkonian, Arek, V; Liu, Zhaoji; Wulf, Gerburg; Arthanari, Haribabu; Qi, Jun; Dhe-Paganon, Sirano; Clohessy, John G.; Choong, Yeu Khai; Sivaraman, J.; Fan, Hao; Tenen, Daniel G.; Chai, Li 分享 收藏
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Effect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals Heng, Yujing J.; Baker, Gabrielle M.; Fein-Zachary, Valerie J.; Guzman-Arocho, Yaileen D.; Bret-Mounet, Vanessa C.; Massicott, Erica S.; Torous, Vanda F.; Schnitt, Stuart J.; Gitin, Sy; Russo, Paul; Tobias, Adam M.; Bartlett, Richard A.; Varma, Gopal; Kontos, Despina; Yaghjyan, Lusine; Irwig, Michael S.; Potter, Jennifer E.; Wulf, Gerburg M. 分享 收藏
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A bedside-to-bench translational analysis demonstrates that NF1 alterations promote CDK4/6 inhibitor (CDK4/6i) resistance in hormone receptor-positive (HR plus ) metastatic breast cancer (MBC) Lloyd, Maxwell; Chica-Parrado, M. Rosario; Knepper, Todd; Lin, Chang-Ching; Podany, Emily; Walko, Christine; Napolitano, Fabiana; Weipert, Caroline; Liao, Jiemin; Medford, Arielle; Ryan, Lianne; Keenan, Jennifer; Zhang, Nicole; Liu, Shiyuan; Wulf, Gerburg; Clifton, Katherine; Ma, Cynthia; Han, Hyo; Ellisen, Leif; Bardia, Aditya; Arteaga, Carlos; Hanker, Ariella; Wander, Seth 分享 收藏
Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth; Nordern, Bryanna; Chevalier, Nicholas; Leshchiner, Ignaty; Stavridi, Anastasia; Kim, Janice; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg; Bardia, Aditya; Spring, Laura; Isakoff, Steven; Lennerz, Jochen; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan; Juric, Dejan 分享 收藏
A phase I trial of the PI3K inhibitor (PI3Ki) copanlisib and fulvestrant in combination with continuous or intermittent abemaciclib in patients with estrogen receptor-positive (ER+), HER2-negative (HER2-) metastatic breast cancer Ma, Cynthia; Luo, Jingqin; Moss, Jessica; Kwa, Maryann; Parajuli, Ritesh; Khoury, Katia; Douglas, Emily; Frith, Ashley; Rigden, Caron; Ademuyiwa, Foluso; Thomas, Shana; Haas, Brittney; Wulf, Gerburg; Dees, Claire; Said, Rabih 分享 收藏
Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry PIN1-APC/CCDH1的相互拮抗作用控制有丝分裂蛋白稳定性和细胞周期进入 Ke, Shizhong; Dang, Fabin; Wang, Lin; Chen, Jia-Yun; Naik, Mandar T.; Li, Wenxue; Thavamani, Abhishek; Kim, Nami; Naik, Nandita M.; Sui, Huaxiu; Tang, Wei; Qiu, Chenxi; Koikawa, Kazuhiro; Batalini, Felipe; Stern Gatof, Emily; Isaza, Daniela Arango; Patel, Jaymin M.; Wang, Xiaodong; Clohessy, John G.; Heng, Yujing J.; Lahav, Galit; Liu, Yansheng; Gray, Nathanael S.; Zhou, Xiao Zhen; Wei, Wenyi; Wulf, Gerburg M.; Lu, Kun Ping 分享 收藏
NCI10217: Phase Ib biomarker-driven tumor-agnostic combination (Combo) trial of copanlisib (Copa) and olaparib (Ola) in molecularly-selected patients (pts) with advanced cancers with PIK3CA hotspot, PTEN and DNA damage response (DDR) mutations Yap, Timothy A.; Dumbrava, Ecaterina E.; Ahnert, Jordi Rodon; Tsimberidou, Apostolia M.; Hong, David; Piha-Paul, Sarina A.; Karp, Daniel D.; Fu, Siqing; Naing, Aung; Pohlmann, Paula; Rhudy, Jessica R.; Berenji-Jalaei, Sheila B.; Cole, Ashley A.; Valladolid, Christian; Dufner, Desirae; Bockorny, Bruno B.; Bullock, Andrea; Fein, Daniel; Buchbinder, Elizabeth; Choudhury, Atish; Haddox, Candace; Lee, Elizabeth; Wulf, Gerburg; Ivy, Percy; Said, Rabih; Shapiro, Geoffrey; Meric-Bernstam, Funda 分享 收藏
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Drug monitoring during ciprofloxacin prophylaxis of allogeneic stem cell transplant patients: associations with bacterial infections through a monocentric observational prospective study Kaba, H. E. J.; Hasenkamp, J.; Tas, H.; Schulz, M.; Streit, F.; Eiffert, H.; Wulf, G.; Truemper, L.; Binder, L.; Kaase, M.; Scheithauer, S. 分享 收藏
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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations 变构PI3Kα 抑制克服了继发性PIK3CA突变介导的对正构抑制剂的靶向抗性 Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Stavridi, Anastasia-Maria; Yuan, Xin; Kim, Janice S.; Ellis, Haley; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian P.; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg M.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Del Vecchio, Kathryn; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan 分享 收藏
Simultaneous isolation of hormone receptor-positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms Hogstrom, Jenny M.; Cruz, Kayla A.; Selfors, Laura M.; Ward, Madelyn N.; Mehta, Tejas S.; Kanarek, Naama; Philips, Jordana; Dialani, Vandana; Wulf, Gerburg; Collins, Laura C.; Patel, Jaymin M.; Muranen, Taru 分享 收藏
Toker Cell Hyperplasia in the Nipple-Areolar Complex of Transmasculine Individuals Baker, Gabrielle M.; Bret-Mounet, Vanessa C.; Xu, Jingxiong; Fein-Zachary, Valerie J.; Tobias, Adam M.; Bartlett, Richard A.; Clohessy, John G.; Vlachos, Ioannis S.; Massicott, Erica S.; Wulf, Gerburg M.; Schnitt, Stuart J.; Heng, Yujing J. 分享 收藏
Olaparib plus /- atezolizumab in patients with BRCA-mutated (BRCAmt) locally advanced unresectable or metastatic (advanced) breast cancer: an open-label, multicenter, randomized phase II trial Fanucci, Kristina A.; Pilat, Mary Jo; Shyr, Derek; Shyr, Yu; Boerner, Scott A.; Durecki, Diane; Noonan, Anne; Abramson, Vandana; Santa-Maria, Cesar; Han, Hyo; Nanda, Rita; Dees, Elizabeth Claire; Park, Haeseong; Buys, Saundra; Peswani, Namrata; Chew, Helen; Assad, Hadeel; Wulf, Gerburg; Richardson, Angelique; Trivedi, Meghna S.; Brufsky, Adam; Abbruzzese, James; Afghahi, Anosheh; Sharon, Elad; Schalper, Kurt; LoRusso, Patricia 分享 收藏
Polymerase theta inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in BRCA-deficient cancers Patterson-Fortin, Jeffrey; Jadhav, Heta; Pantelidou, Constantia; Phan, Tin; Grochala, Carter; Mehta, Anita K.; Guerriero, Jennifer L.; Wulf, Gerburg M.; Wolpin, Brian M.; Stanger, Ben Z.; Aguirre, Andrew J.; Cleary, James M.; D'Andrea, Alan D.; Shapiro, Geoffrey I. 分享 收藏
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