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J

J. G. Coen van Hasselt

Leiden University

33H指数
174论文数
3.9K被引数
收录论文 103
发表时间
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Population Pharmacokinetic and Exposure-Response Analysis of Vancomycin Nephrotoxicity in Cystic Fibrosis Patients万古霉素肾毒性在囊性纤维化患者中的群体药代动力学和暴露-反应分析
errPediatric Pulmonology
IF2.3
err2026-09-30
err0
errOAAI
errJessica Barry; J. G. C. van Hasselt; Michael Evans; Elizabeth B. Hirsch; Jordan Dunitz; Sarah Shockley; Joanne Billings; Sílvia M. Illamola
err分享
err收藏
In reply to the letter to editor regarding: Strain-dependent variability in pharmacodynamic interactions for phage-antibiotic combinations in Pseudomonas aeruginosa针对关于铜绿假单胞菌中噬菌体-抗生素组合的药效学相互作用菌株依赖性变异的致编辑信的回复
errInternational Journal of Antimicrobial Agents
IF4.6
err2026-09-01
err0
PREAI
errBaars, Laura R.; Gu, Meng; Guo, Tingjie; Hasselt, J. G. Coen van
err分享
err收藏
Successful Translational Prediction of Bedaquiline's Phase 2a Clinical Trial Results against Tuberculosis: The Zebrafish as a New Approach Methodology成功预测贝达喹啉2a期临床试验结果对结核病的转化：斑马鱼作为一种新的方法学
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2026-08-29
err0
errOAAI
errBart van Lieshout; Aanisah Hanuun; J. G. Coen van Hasselt; Rob C. van Wijk
err分享
err收藏
Do Brain Extracellular Fluid Concentrations Predict PET-Inferred Receptor Occupancy in Human CNS? A Mechanistic Model-Based Analysis of Dopamine D2 Receptor Ligands脑部细胞外液浓度能否预测PET推断的人体中枢神经系统受体占有率？基于多巴胺D2受体配体的机制模型分析
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2026-08-27
err0
errOAAI
errDivakar Budda; J.G. Coen van Hasselt; Elizabeth C.M. de Lange
err分享
err收藏
Collateral sensitivity identified in surveillance data shows limited reproducibility in clinical isolates在监测数据中识别出的伴生敏感性在临床分离株中显示出有限的重复性
errLancet Microbe
IF20.4
err2026-08-05
err0
errOAAI
errJohan G C van Hasselt; Sebastian T Tandar; Wiep Klaas Smits; Apostolos Liakopoulos; Laura B Zwep; Linda B S Aulin
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err收藏
Pharmacodynamic modeling of colistin and imipenem against in vitro Pseudomonas aeruginosa biofilms体外铜绿假单胞菌生物膜中多黏菌素和美罗培南的药效学模型
errBiofilm
IF4.9
err2026-08-01
err0
PREAI
errGuo, Yuchen; Yin, Jinqiu; Aulin, Linda B. S.; Ciofu, Oana; Moser, Claus; Upadhyay, Parth J.; Hoiby, Niels; Wang, Hengzhuang; Guo, Tingjie; van Hasselt, J. G. Coen
err分享
err收藏
Ribavirin post-exposure prophylaxis for Andes virus exposure: a viewpoint利巴韦林暴露后预防用于安第斯病毒暴露：一种观点
errEBioMedicine
IF10.8
err2026-07-16
err0
errOAAI
errRoger J. Brüggemann; Albert Vollaard; Sacha de Stoppelaar; Johan G.C. van Hasselt; David M. Burger; Job J. Engel; Jeroen J.A. van Kampen; Matthew McCall; Loek Smits; Hetty Jolink; Leo G. Visser; Frank van de Veerdonk; Karin Ellen Veldkamp; Chantal P. Rovers; Rob J.W. Arts
err分享
err收藏
Strain-dependent variability in pharmacodynamic interactions for phage-antibiotic combinations in Pseudomonas aeruginosa铜绿假单胞菌中噬菌体-抗生素组合的药效学相互作用存在菌株依赖性变异性
errInternational Journal of Antimicrobial Agents
IF4.6
err2026-07-01
err2
PREAI
errBaars, Laura R.; Gu, Meng; Guo, Tingjie; van Hasselt, J. G. Coen
err分享
err收藏
Copulas for Covariate Simulation in Pharmacometrics用于药代动力学协变量模拟的Copulas
errcpt: pharmacometrics & systems pharmacology
IF0
err2026-04-14
err0
errOAAI
errYuchen Guo; Tingjie Guo; J. G. Coen van Hasselt; Laura B. Zwep
err分享
err收藏
Experimental and Virus-Specific Drivers of EC50 Variability in Antiviral Assays Evaluated Using Mathematical Modeling使用数学模型评估的抗病毒测定中EC50变异性的实验和病毒特异性驱动因素
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2026-02-19
err0
errOAAI
errChenyu Wang; Qinhao Wu; Xuanlin Liu; Lalitya M. Sudarsono; Anne-Grete Märtson; J.G.C. van Hasselt
err分享
err收藏
Aggregate data modelling: A fast implementation for fitting pharmacometrics models to summary-level data in R聚合数据建模：一种在R中快速实现将药代动力学模型拟合到汇总级数据的方案
errJOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
IF2.8
err2025-12-09
err0
PREAI
errvan de Beek, Hidde; Valitalo, Pyry A. J.; van Hasselt, J. G. Coen; Zwep, Laura B.
err分享
err收藏
Model-based optimisation for teicoplanin dosing in patients undergoing maintenance haemodialysis基于模型的替考拉宁给药优化用于接受维持性血液透析的患者
errClinical Microbiology and Infection
IF8.5
err2025-12-02
err0
PREAI
errSebastian T. Tandar; Arnaud De Clercq; Linda B.S. Aulin; Wim Van Biesen; Sigurd Delanghe; Floris Vanommeslaeghe; Peter De Paepe; J.G.Coen van Hasselt; Pieter A. De Cock; Sunny Eloot
err分享
err收藏
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety定量系统毒理学: 建模以机械地理解和预测药物安全性
errNature Reviews Drug Discovery
IF101.8
err2025-10-27
err0
PREAI
errChristopher E. Goldring; Giusy Russomanno; Carmen Pin; Panuwat Trairatphisan; Kylie A. Beattie; Ciarán P. Fisher; Janet Piñero; Richard J. Brennan; Diana Clausznitzer; Ian M. Copple; Theo M. de Kok; Carrie A. Duckworth; Laura I. Furlong; Barbara Füzi; Attila Gabor; Louis Gall; Jan Hengstler; Henning Hermjakob; Fiona Hunter; Danyel Jennen; Mikko Koskinen; Steven J. Kunnen; Lieve Lammens; Sebastian Lobentanzer; Marcel Mohr; Elisa Passini; D. Mark Pritchard; Rahuman S. Malik-Sheriff; Blanca Rodríguez; Eric I. Rossman; Julio Saez-Rodríguez; Friedemann Schmidt; Rowena Sison-Young; Inari Soininen; Sean Turner; Bob van de Water; Johan G. C. van Hasselt; Filippo Venezia; Jeffrey A. Willy; Derek J. Leishman; James L. Stevens; Loic Laplanche
err分享
err收藏
Spatial Pharmacokinetic and Pharmacodynamic Modeling in Airway Mucus气道黏液中的空间药代动力学和药效动力学建模
errClinical Pharmacokinetics
IF4
err2025-10-06
err0
errOAAI
errYuchen Guo; Jinqiu Yin; Sirin Yonucu; Catherijne A. J. Knibbe; Tingjie Guo; J. G. Coen van Hasselt
err分享
err收藏
Beta-endorphin is the key endogenous opioid influencing morphine µ-opioid receptor occupancy in rat hypothalamus: a binding kinetic model analysisβ-内啡肽是影响大鼠下丘脑中吗啡μ-阿片受体占据率的关键内源性阿片肽：一项结合动力学模型分析
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-07-10
err0
errOAAI
errDivakar Budda; Zhicheng Zhang; J.G. Coen van Hasselt; Elizabeth C.M. de Lange
err分享
err收藏
Integrating Pharmacokinetics and Quantitative Systems Pharmacology Approaches in Generative Drug Design整合药代动力学和定量系统药理学方法在生成式药物设计中的应用
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-05-09
err0
errOAAI
errvan den Maagdenberg, Helle W.; de Mol van Otterloo, Jikke; van Hasselt, J. G. Coen; van der Graaf, Piet H.; van Westen, Gerard J. P.
err分享
err收藏
Target attainment of benzylpenicillin in patients with infective endocarditis苯唑西林在感染性心内膜炎患者中的目标达标情况
errClinical Microbiology and Infection
IF8.5
err2025-04-28
err0
PREAI
errMagnus Bock; Johan G.C. Van Hasselt; Kurt Fuursted; Nikolaj Ihlemann; Sabine Gill; Ulrik Christiansen; Niels Eske Bruun; Hanne Elming; Jonas A. Povlsen; Lars Køber; Dan E. Høfsten; Emil L. Fosbøl; Mia M. Pries-Heje; Jens Jørgen Christensen; Flemming S. Rosenvinge; Christian Torp Pedersen; Jannik Helweg-Larsen; Niels Tønder; Kasper Iversen; Henning Bundgaard; Claus Moser
err分享
err收藏
Prediction of the Extent of Blood-Brain Barrier Transport Using Machine Learning and Integration into the LeiCNS-PK3.0 Model
errPHARMACEUTICAL RESEARCH
IF4.3
err2025-02-10
err0
errOAAI
errGulave, Berfin; van den Maagdenberg, Helle W.; van Boven, Luke; van Westen, Gerard J. P.; de Lange, Elizabeth C. M.; van Hasselt, J. G. Coen
err分享
err收藏
Clinical Pharmacokinetics of N,N-Dimethyltryptamine (DMT): A Systematic Review and Post-hoc AnalysisN,N-二甲基色胺（DMT）的临床药代动力学：一项系统评价和事后分析
errCLINICAL PHARMACOKINETICS
IF4
err2025-01-21
err3
errOAAI
errvan der Heijden, K. V.; Otto, M. E.; Schoones, J. W.; van Esdonk, M. J.; Borghans, L. G. J. M.; van Hasselt, J. G. C.; van Gerven, J. M. A.; Jacobs, G.
err分享
err收藏
Pharmacodynamics of interspecies interactions in polymicrobial infections多微生物感染中种间相互作用的药效学
errNPJ BIOFILMS AND MICROBIOMES
IF9.2
err2025-01-21
err1
errOAAI
errHerzberg, C.; van Hasselt, J. G. C.
err分享
err收藏

研究方向

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