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Stephen Gottschalk

St Jude Children's Research Hospital

77H指数
689论文数
2.1W被引数
收录论文 178
发表时间
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CD19-CAR T cells persist long-term in the cerebrospinal fluid of pediatric, adolescent and young adult patients with B-cell acute lymphoblastic leukemiaCD19-CAR T细胞在患有B细胞急性淋巴细胞白血病的儿童、青少年和年轻成年患者的脑脊液中长期持续存在
errLeukemia
IF13.4
err2026-09-03
err0
errOAAI
errAimee C. Talleur; Jean-Yves Métais; Ying Li; Sarah Schell; Polly Adams; Rebecca Epperly; Marleni Torres Nunez; Stephen Gottschalk; Swati Naik
err分享
err收藏
Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma靶向B7-H3-CAR T细胞中的Regnase-1重编程肿瘤微环境并增强对骨肉瘤的抗肿瘤功效
errCell Reports Medicine
IF10.6
err2026-09-01
err0
PREAI
errAdeshakin, Adeleye O.; Shi, Hao; Perry, S. Scott; Sheppard, Heather; Nguyen, Phuong; Sun, Xiang; Zhou, Peipei; Metais, Jean-Yves; Cunningham, Trevor; Anil, K. C.; Tian, Liqing; Peche, Vivek; Prater, Mollie S.; Langfitt, Deanna M.; O'Reilly, Carla; Park, Jeoungeun J.; Chabot, Ashley; Zhou, Sheng; Matsubara, Azusa; Lee, GaHyun; Tsai, Shengdar Q.; Pruett-Miller, Shondra M.; Talbot, Lindsay J.; Yustein, Jason T.; Krenciute, Giedre; DeRenzo, Christopher; Chi, Hongbo; Gottschalk, Stephen
err分享
err收藏
Blood Rheology After Allogeneic Hematopoietic Stem Cell Transplantation or Gene Therapy in Sickle Cell Disease异基因造血干细胞移植或基因疗法后镰状细胞病患者的血液流变学
errBlood Advances
IF7.1
err2026-07-16
err0
errOAAI
errAshwin P. Patel; Tami D. John; Stephen Gottschalk; Brandon M. Triplett; Serena De Vita; Elizabeth O. Stenger; Akshay Sharma; Vivien A. Sheehan
err分享
err收藏
Costimulation drives CAR-T cell division fate共刺激驱动CAR-T细胞分裂命运
errNature Immunology
IF27.6
err2026-06-22
err0
PREAI
errAdeleye O. Adeshakin; Stephen Gottschalk
err分享
err收藏
Mining single-cell transcriptomic data reveals distinct T-cell population in pediatric B-ALL and AML at diagnosis挖掘单细胞转录组数据揭示儿童B-ALL和AML初诊时独特的T细胞群体
errBlood Advances
IF7.1
err2026-04-16
err0
errOAAI
errLiqing Tian; Stephen Gottschalk
err分享
err收藏
Cell therapy for brain tumors: The first 60 years脑肿瘤的细胞疗法：前60年
errCell Reports Medicine
IF10.6
err2026-02-17
err0
errOAAI
errSanya Mehta; Giedre Krenciute; Stephen Gottschalk
err分享
err收藏
Roads and detours for CAR T cell therapy in autoimmune diseases自身免疫性疾病中CAR T细胞治疗的道路和弯路
errNature Reviews Drug Discovery
IF101.8
err2026-01-26
err0
PREAI
errJérôme Avouac; Adi Barzel; Delma Caiati; Randall S. Davis; Stephen Gottschalk; Ricardo Grieshaber-Bouyer; Xuming Mao; Eline T. Luning Prak; Marko Radic; Marc Scherlinger; Yatin Suneja; Aimee Talleur; Amber L. Thacker; Derya Unutmaz
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BACH2 regulates T cell lineage state to enhance CAR T cell functionBACH2调节T细胞谱系状态以增强CAR T细胞功能
errNature Immunology
IF27.6
err2026-01-16
err0
PREAI
errTien-Ching Chang; Amanda Heard; John Lattin; John M. Warrington; Amanda Barrett; Jack H. Landmann; Yangdon Tenzin; Vishaal Ganesh; Bryant Thompson; Sadia Afrin; Deepesh Kumar Gupta; Ju-Fang Chang; Julie Ritchey; Mehmet Emrah Selli; Yu-Sung Hsu; Haorui Song; A. J. Federico; Avery Horn; Michael P. Meers; Evan W. Weber; Thomas J. Wandless; Jeremy Chase Crawford; Paul G. Thomas; John F. DiPersio; Stephen Gottschalk; Nathan Singh
err分享
err收藏
Tumor mechanics mediated suppression against CAR T cells in diffuse midline gliomas弥漫性中线胶质瘤中肿瘤力学介导的对CAR T细胞的抑制
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errSinha, Sauradeep; Fleck, Mark; Teis, Robert; Meehl, Michaela; Chockley, Peter; Ward, Meghan; Adeshakin, Adeleye; Jones, Sarah; Gottschalk, Stephen; Yang, Fan; Krenciute, Giedre
err分享
err收藏
Pediatric Acute Myeloid Leukemia-associated S100A9 Drives T Cell Dysfunction
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errWard, Grace A.; Bruno, Tyler G.; Mi, Tian; Velasquez, Paulina; Naik, Swati; Alli, Shanta; Kang, Tae Gun; You, Zhiyuan; Vasandan, Anoop Babu; Langfitt, Deanna M.; Lear, Matthew; Gottschalk, Stephen; Chi, Hongbo; Kanneganti, Thirumala-Devi; Zebley, Caitlin C.; Youngblood, Ben A.
err分享
err收藏
Evaluation of B7-H3-CAR T cells expressing leucine zipper-based cytokine receptors in immunocompetent mouse models
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errSong, Xirui; Wagner, Jessica; Adeshakin, Adeleye Oluwatosin; Prinzing, Brooke; Martin, Reid; Metais, Jean-Yves; Gottschalk, Stephen
err分享
err收藏
Transgenic expression of mutated CD47 enables CD47-CAR T cell persistence and antitumor activity in vivo
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errTuladhar, Shraddha; Beckett, Alexandra N.; Nguyen, Phuong; Oreilly, Carla M.; Gottschalk, Stephen; Derenzo, Christopher
err分享
err收藏
Increased capacity for expansion, not persistence, improves preclinical B7-H3 targeted CAR T cell therapy against aggressive Group 3 medulloblastomas扩增能力而非持久性增强，可改善针对侵袭性Group 3髓母细胞瘤的B7-H3靶向CAR T细胞疗法的前临床效果
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errWard, Meghan; Meehl, Michaela; Senaoui, Linda; Park, Jeoungeun John; Ibanez-Vega, Jorge; Dovidonyte, Rugile; Kujur, Weshely; Zhou, Sheng; Bertrand, Kelsey; Derenzo, Christopher; Gottschalk, Stephen; Roussel, Martine; Youngblood, Benjamin; Chi, Hongbo; Krenciute, Giedre
err分享
err收藏
CELL-FREE DNA ANALYSIS OF CSF SAMPLES ENABLES ASSESSMENT OF TREATMENT RESPONSE AND TRACKING OF CAR T-CELLS POST-LOCOREGIONAL DELIVERY IN PEDIATRIC BRAIN TUMOR PATIENTS脑脊液样本的无细胞DNA分析能够评估治疗反应，并追踪在儿科脑肿瘤患者中局部区域给药后的CAR T细胞。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errKostecka, Anna; Smith, Kyle S.; Han, Katie; Martin, Vincentius; Lin, Hong; Langfitt, Deanna; Ward, Meghan B.; Walhart, Tara; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher; Bertrand, Kelsey C.; Northcott, Paul A.
err分享
err收藏
Locoregional B7-H3 CAR-T cells for relapsed/refractory CNS tumors: preliminary clinical experience of the Loc3CAR trial局部区域B7-H3 CAR-T细胞治疗复发/难治性中枢神经系统肿瘤：Loc3CAR试验的初步临床经验
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errBertrand, Kelsey; Hanzlik, Emily; Chiang, Jason; Pinto, Soniya; Selukar, Subodh; Kosteka, Anna; Smith, Kyle; Han, Katie; Ibanez, Jorge; Tlais, Dana; Orr, Brent; Langfitt, Deanna; Metais, Jean-Yves; Lockey, Timothy; Willis, Catherine; Fazio, Frank; Shanmugmam, Raghu; Tian, Liqing; Walhart, Tara; Wang, Yu; Allmon, Patricia; Perry, Scott; Schell, Sarah; Adams, Polly; Ward, Meghan; Meehl, Michaela; Akel, Salem; Poston, Leigh; Bag, Asim; Mack, Stephen; Klimo, Paul; Gajjar, Amar; Thomas, Paul; Crawford, Jeremy; Robinson, Giles; Park, Julie; Northcott, Paul; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher
err分享
err收藏
Tumor inflammation-associated neurotoxicities for patients treated with intracranial B7-H3-CAR T cells on a phase I clinical trialI期临床试验中接受颅内B7-H3-CAR T细胞治疗的患者的肿瘤炎症相关神经毒性
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errHanzlik, Emily M.; Bertrand, Kelsey C.; Chiang, Jason; Pinto, Soniya; Khan, Raja B.; Solanki, Arun; Selukar, Subodh; Wang, Yu; Bakare, Deborah; Swartz, Kate; Gajjar, Amar; Robinson, Giles W.; Park, Julie R.; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher
err分享
err收藏
De novo generation of innate memory-like T cells occur early during human immune development
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errVasandan, Anoop Babu; Abdelsamed, Hossam Aly; Boi, Shannon K.; Ward, Grace A.; Alli, Shanta; Mi, Tian; Lan, Xin; Zhang, Xusheng; Cowan, Morton J.; Puck, Jennifer M.; Petrovic, Aleksandra; Rawlings, David J.; Zhou, Albert; Mamcarz, Ewelina; Gottschalk, Stephen; Zebley, Caitlin C.; Youngblood, Ben A.
err分享
err收藏
Cytotoxic bystander activation of endogenous CAR-negative T cells in response to CD19-CAR T cell therapy
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errQu, Jia-Hua; Langfitt, Deanna; Chou, Ching-Heng; Kim, Hyunjin; Wilson, Taylor Leigh; Allen, Kaity; Talleur, Aimee; Gottschalk, Stephen; Thomas, Paul Glyndwr; Crawford, Jeremy Chase
err分享
err收藏
International consensus guidelines for the conduct and reporting of CAR T-cell clinical trials in AML国际共识指南：关于AML CAR T细胞临床研究的实施与报告
errBlood Advances
IF7.1
err2025-08-21
err0
errOAAI
errSwati Naik; Richard Aplenc; Susanne H.C. Baumeister; Marco Becilli; Anand S. Bhagwat; Challice L. Bonifant; Lihua E. Budde; Christopher D. Chien; Kevin J. Curran; Anthony F. Daniyan; Alexandra Dreyzin; Rebecca A. Gardner; Sara Ghorashian; Stephen Gottschalk; LaQuisa C. Hill; M. Eric Kohler; Adam Lamble; Franco Locatelli; Maksim Mamonkin; Bilal Omer
err分享
err收藏
Innate-like memory T cells rapidly emerge in humans after gene therapy for SCID-X1类先天记忆T细胞在X1联合免疫缺陷症基因治疗后迅速出现在人类体内
errImmunity
IF26.3
err2025-07-31
err0
errOAAI
errAnoop Babu Vasandan; Hossam A. Abdelsamed; Shannon K. Boi; Grace Ward; Shanta Alli; Tian Mi; Xin Lan; Xusheng Zhang; Morton J. Cowan; Jennifer M. Puck; Aleksandra Petrovic; David Rawlings; Albert Zhou; Ewelina Mamcarz; Stephen Gottschalk; Caitlin C. Zebley; Ben Youngblood
err分享
err收藏

研究方向

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