Christopher G. Tate - Publications, H-index & Citations

Christopher G. Tate

francis crick institute

65H指数

211论文数

1.8W被引数

收录论文 60

发表时间

De novo design of miniproteins targeting GPCRs 从头设计靶向GPCRs的迷你蛋白

Nature

IF48.5

2026-05-21

PREAI

Edin Muratspahić; David Feldman; David E. Kim; Xiangli Qu; Ana-Maria Bratovianu; Paula Rivera-Sánchez; Jan Hendrik Voss; Emil P. T. Hertz; Mads Jeppesen; Federica Dimitri; Kensuke Sakamoto; Amrita Nallathambi; Pia Peceli; Jianjun Cao; Brian P. Cary; Matthew J. Belousoff; Peter Keov; Phuc N. H. Trinh; Qingchao Chen; Yue Ren; Justyn Fine; Sudha Mishra; Annu Dalal; Shachie Sinha; Ramanuj Banerjee; Manisankar Ganguly; Karthik Varappalayam Karuppusamy; Isaac Sappington; Thomas Schlichthaerle; Jason Z. Zhang; Arvind Pillai; Brian Coventry; Ljubica Mihaljević; Magnus Bauer; Susana Vázquez Torres; Amir Motmaen; Gyu Rie Lee; Long Tran; Xinru Wang; Inna Goreshnik; Dionne K. Vafeados; Justin E. Svendsen; Parisa Hosseinzadeh; Nicolai Lindegaard; Matthäus Brandt; Yann Waltenspühl; Kristine Deibler; Lukas Deweid; Anja Bennett; Jendrik Schöppe; Tiantang Dong; Xiaoli Yan; Luke Oostdyk; William Cao; Lakshmi Anantharaman; Johan J. Weisser; Jesper Frank Bastlund; Christoffer Bundgaard; Ayodeji A. Asuni; Justin G. English; Lance Stewart; Lauren Halloran; Jamie B. Spangler; André Lieber; Arun K. Shukla; Patrick M. Sexton; Bryan L. Roth; Brian E. Krumm; Denise Wootten; Christopher G. Tate; Christoffer Norn; David Baker

Structure of the Gq-coupled adhesion receptor ADGRL4 Gq偶联的粘附受体ADGRL4的结构

Nature Communications

IF15.7

2025-12-30

OAAI

Qingchao Chen; Anastasiia Gusach; Aurora Diamante; Jayesh C. Patel; Patricia C. Edwards; Christopher G. Tate; David M. Favara

Carvedilol Activates a Myofilament Signaling Circuitry to Restore Cardiac Contractility in Heart Failure

JACC-BASIC TO TRANSLATIONAL SCIENCE

IF7.2

2024-08-01

OAAI

Wang, Ying; Zhao, Meimi; Liu, Xianhui; Xu, Bing; Reddy, Gopireddy R.; Jovanovic, Aleksandra; Wang, Qingtong; Zhu, Chaoqun; Xu, Heli; Bayne, Elizabeth F.; Xiang, Wenjing; Tilley, Douglas G.; Ge, Ying; Tate, Christopher G.; Feil, Robert; Chiu, Joanna C.; Bers, Donald M.; Xiang, Yang K.

New insights into GPCR coupling and dimerisation from cryo-EM structures

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-06-01

OAAI

Gusach, Anastasiia; Garcia-Nafria, Javier; Tate, Christopher G.

Developing novel antifungals: lessons from G protein-coupled receptors

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2023-03-01

OAAI

Velazhahan, Vaithish; McCann, Bethany L.; Bignell, Elaine; Tate, Christopher G.

Structure determination of GPCRs: cryo-EM compared with X-ray crystallography

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2021-09-28

OAAI

Garcia-Nafria, Javier; Tate, Christopher G.

High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-07-29

OAAI

Wu, Na; Olechwier, Agnieszka M.; Brunner, Cyrill; Edwards, Patricia C.; Tsai, Ching-Ju; Tate, Christopher G.; Schertler, Gebhard F. X.; Schneider, Gisbert; Deupi, Xavier; Zenobi, Renato; Ma, Pikyee

Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles

NANOSCALE

IF5.1

2021-01-01

OAAI

Grime, Rachael L.; Logan, Richard T.; Nestorow, Stephanie A.; Sridhar, Pooja; Edwards, Patricia C.; Tate, Christopher G.; Klumperman, Bert; Dafforn, Tim R.; Poyner, David R.; Reeves, Philip J.; Wheatley, Mark

Cryo-Electron Microscopy: Moving Beyond X-Ray Crystal Structures for Drug Receptors and Drug Development

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY

IF0

2020-01-06

PREAI

Garcia-Nafria, Javier; Tate, Christopher G.

Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors

BIOPHYSICAL JOURNAL

IF3.1

2019-12-01

OAAI

Muk, Sanychen; Ghosh, Soumadwip; Achuthan, Srisairam; Chen, Xiaomin; Yao, XiaoJie; Sandhu, Manbir; Griffor, Matthew C.; Fennell, Kimberly F.; Che, Ye; Shanmugasundaram, Veerabahu; Qiu, Xiayang; Tate, Christopher G.; Vaidehi, Nagarajan

Cryo-EM structures of GPCRs coupled to Gs, Gi and Go

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2019-05-01

122

PREAI

Garcia-Nafria, Javier; Tate, Christopher G.

Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity

SCIENCE ADVANCES

IF12.5

2018-09-07

OAAI

Tsai, Ching-Ju; Pamula, Filip; Nehme, Rony; Muhle, Jonas; Weinert, Tobias; Flock, Tilman; Nogly, Przemyslaw; Edwards, Patricia C.; Carpenter, Byron; Gruhl, Thomas; Ma, Pikyee; Deupi, Xavier; Standfuss, Jorg; Tate, Christopher G.; Schertler, Gebhard F. X.

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein

ELIFE

IF0

2018-05-04

203

OAAI

Garcia-Nafria, Javier; Lee, Yang; Bai, Xiaochen; Carpenter, Byron; Tate, Christopher G.

Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells 用于活细胞中活性g蛋白偶联受体 (gpcr) 的微型g蛋白探针

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-05-01

264

OAAI

Wan, Qingwen; Okashah, Najeah; Inoue, Asuka; Nehme, Rony; Carpenter, Byron; Tate, Christopher G.; Lambert, Nevin A.

Dynamic Behaviors of Various Conformational States of A2A Receptor

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Lee, Sangbae; Nivedha, Anita K.; Tate, Christopher; Vaidehi, Nagarajan

Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor

NATURE COMMUNICATIONS

IF15.7

2017-11-27

OAAI

Solt, Andras S.; Bostock, Mark J.; Shrestha, Binesh; Kumar, Prashant; Warne, Tony; Tate, Christopher G.; Nietlispach, Daniel

Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2017-08-01

OAAI

Carpenter, Byron; Tate, Christopher G.

STRUCTURAL BIOLOGY A receptor that might block itself

NATURE

IF48.5

2017-04-05

OAAI

Tate, Christopher G.

How Do Short Chain Nonionic Detergents Destabilize G-Protein-Coupled Receptors?

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-11-15

OAAI

Lee, Sangbae; Mao, Allen; Bhattacharya, Supriyo; Robertson, Nathan; Grisshammer, Reinhard; Tate, Christopher G.; Vaidehit, Nagarajan

A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

NATURE PROTOCOLS

IF16

2016-07-28

OAAI

Magnani, Francesca; Serrano-Vega, Maria J.; Shibata, Yoko; Abdul-Hussein, Saba; Lebon, Guillaume; Miller-Gallacher, Jennifer; Singhal, Ankita; Strege, Annette; Thomas, Jennifer A.; Tate, Christopher G.

研究方向