Tomasz Róg - Publications, H-index & Citations

Tomasz Róg

Tampere University

62H指数

240论文数

1.3W被引数

收录论文 98

发表时间

Mechanistic Understanding from Molecular Dynamics in Pharmaceutical Research 2: Lipid Membrane in Drug Design 药物研究中分子动力学的机理理解2: 药物设计中的脂质膜

PHARMACEUTICALS

IF4.8

2021-10-19

OAAI

Rog, Tomasz; Girych, Mykhailo; Bunker, Alex

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors 抗抑郁药通过直接与TRKB神经营养因子受体结合而起作用

CELL

IF42.5

2021-03-01

381

OAAI

Casarotto, Plinio C.; Girych, Mykhailo; Fred, Senem M.; Kovaleva, Vera; Moliner, Rafael; Enkavi, Giray; Biojone, Caroline; Cannarozzo, Cecilia; Sahu, Madhusmita Pryiadrashini; Kaurinkoski, Katja; Brunello, Cecilia A.; Steinzeig, Anna; Winkel, Frederike; Patil, Sudarshan; Vestring, Stefan; Serchov, Tsvetan; Diniz, Cassiano R. A. F.; Laukkanen, Liina; Cardon, Iseline; Antila, Hanna; Rog, Tomasz; Piepponen, Timo Petteri; Bramham, Clive R.; Normann, Claus; Lauri, Sari E.; Saarma, Mart; Vattulainen, Ilpo; Castren, Eero

Mechanistic Understanding From Molecular Dynamics Simulation in Pharmaceutical Research 1: Drug Delivery

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2020-11-25

OAAI

Bunker, Alex; Rog, Tomasz

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering

JOURNAL OF CELL SCIENCE

IF3.6

2020-10-12

OAAI

Kukkurainen, Sampo; Azizi, Latifeh; Zhang, Pingfeng; Jacquier, Marie-Claude; Baikoghli, Mo; von Essen, Magdalena; Tuukkanen, Anne; Laitaoja, Mikko; Liu, Xiaonan; Rahikainen, Rolle; Orlowski, Adam; Janis, Janne; Maatt, Juha A. E.; Varjosalo, Markku; Vattulainen, Ilpo; Rog, Tomasz; Svergun, Dmitri; Cheng, R. Holland; Wu, Jinhua; Hytonen, Vesa P.; Wehrle-Haller, Bernhard

Rigorous Computational Study Reveals What Docking Overlooks: Double Trouble from Membrane Association in Protein Kinase C Modulators 严格的计算研究揭示了对接所忽略的: 蛋白激酶C调节剂中膜缔合的双重麻烦

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-09-11

PREAI

Lautala, Saara; Provenzani, Riccardo; Koivuniemi, Artturi; Kulig, Waldemar; Talman, Virpi; Rog, Tomasz; Tuominen, Raimo K.; Yli-Kauhaluoma, Jari; Bunker, Alex

Tail-Oxidized Cholesterol Enhances Membrane Permeability for Small Solutes 尾部氧化的胆固醇增强了小溶质的膜通透性

LANGMUIR

IF3.9

2020-08-17

OAAI

Olzynska, Agnieszka; Kulig, Waldemar; Mikkolainen, Heikki; Czerniak, Tomasz; Jurkiewicz, Piotr; Cwiklik, Lukasz; Rog, Tomasz; Hof, Martin; Jungwirth, Pavel; Vattulainen, Ilpo

Membrane-Dependent Binding and Entry Mechanism of Dopamine into Its Receptor 多巴胺与其受体的膜依赖性结合和进入机制

ACS CHEMICAL NEUROSCIENCE

IF3.9

2020-06-15

OAAI

Lolicato, Fabio; Juhola, Hanna; Zak, Agata; Postila, Pekka A.; Saukko, Annina; Rissanen, Sami; Enkavi, Giray; Vattulainen, Ilpo; Kepczynski, Mariusz; Rog, Tomasz

Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway Syndecan-4通过激活kindlin-整合素-RhoA途径调节细胞力学

NATURE MATERIALS

IF38.5

2020-01-06

OAAI

Chronopoulos, Antonios; Thorpe, Stephen D.; Cortes, Ernesto; Lachowski, Dariusz; Rice, Alistair J.; Mykuliak, Vasyl V.; Rog, Tomasz; Lee, David A.; Hytonen, Vesa P.; Hernandez, Armando E. del Rio

Behavior of the DPH fluorescence probe in membranes perturbed by drugs DPH荧光探针在药物干扰膜中的行为

CHEMISTRY AND PHYSICS OF LIPIDS

IF2.8

2019-09-01

OAAI

Poojari, Chetan; Wilkosz, Natalia; Lira, Rafael B.; Dimova, Rumiana; Jurkiewicz, Piotr; Petka, Rafal; Kepczynski, Mariusz; Rog, Tomasz

Complex Behavior of Phosphatidylcholine-Phosphatidic Acid Bilayers and Monolayers: Effect of Acyl Chain Unsaturation 磷脂酰胆碱-磷脂酸双层和单层的复杂行为: 酰基链不饱和的影响

LANGMUIR

IF3.9

2019-04-03

OAAI

Kulig, Waldemar; Korolainen, Hanna; Zatorska, Maria; Kwolek, Urszula; Wydro, Pawel; Kepczynski, Mariusz; Rog, Tomasz

Itraconazole Perturbs Behavior of Fluorescent Probes in Lipid Bilayer

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

PREAI

Poojari, Chetan; Wilkosz, Natalia; Jurkiewicz, Piotr; Vattulainen, Ilpo; Kepczynski, Mariusz; Rog, Tomasz

Cholesterol-dependent effect of antidepressants on activation BDNF receptor (TRKB)

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2019-01-01

PREAI

Casarotto, P.; Fred, S. M.; Biojone, C.; Girych, M.; Rog, T.; Vattulainen, I.; Castren, E.

Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico

SCIENTIFIC REPORTS

IF3.9

2018-09-11

OAAI

Mobarak, Edouard; Haversen, Liliana; Manna, Moutusi; Rutberg, Mikael; Levin, Malin; Perkins, Rosie; Rog, Tomasz; Vattulainen, Ilpo; Boren, Jan

How cardiolipin peroxidation alters the properties of the inner mitochondrial membrane?心磷脂过氧化如何改变线粒体内膜的性质？

CHEMISTRY AND PHYSICS OF LIPIDS

IF2.8

2018-08-01

OAAI

Vahaheikkila, Marjut; Peltomaa, Tapio; Rog, Tomasz; Vazdar, Mario; Poyry, Sanja; Vattulainen, Ilpo

Membrane bound COMT isoform is an interfacial enzyme: general mechanism and new drug design paradigm 膜结合COMT同工型是一种界面酶: 一般机制和新的药物设计范式

CHEMICAL COMMUNICATIONS

IF4.2

2018-01-01

PREAI

Magarkar, Aniket; Parkkila, Petteri; Viitala, Tapani; Lajunen, Tatu; Mobarak, Edouard; Licari, Giuseppe; Cramariuc, Oana; Vauthey, Eric; Rog, Tomasz; Bunker, Alex

doGlycans-Tools for Preparing Carbohydrate Structures for Atomistic Simulations of Glycoproteins, Glycolipids, and Carbohydrate Polymers for GROMACS Dglycoans-用于制备碳水化合物结构的工具，用于GROMACS的糖蛋白，糖脂和碳水化合物聚合物的原子模拟

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2017-10-12

OAAI

Danne, Reinis; Poojari, Chetan; Martinez-Seara, Hector; Rissanen, Sami; Lolicato, Fabio; Rog, Tomasz; Vattulainen, Ilpo

Dynamics and energetics of the mammalian phosphatidylinositol transfer protein phospholipid exchange cycle

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-09-01

OAAI

Grabon, Aby; Orlowski, Adam; Tripathi, Ashutosh; Vuorio, Joni; Javanainen, Matti; Rog, Tomasz; Lonnfors, Max; McDermott, Mark I.; Siebert, Garland; Somerharju, Pentti; Vattulainen, Ilpo; Bankaitis, Vytas A.

Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin

FRONTIERS IN PHYSIOLOGY

IF3.4

2017-05-09

OAAI

Rissanen, Sami; Grzybek, Michal; Orlowski, Adam; Rog, Tomasz; Cramariuc, Oana; Levental, Ilya; Eggeling, Christian; Sezgin, Erdinc; Vattulainen, Ilpo

A computational study suggests that replacing PEG with PMOZ may increase exposure of hydrophobic targeting moiety 一项计算研究表明，用PMOZ代替PEG可能会增加疏水性靶向部分的暴露

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2017-05-01

PREAI

Magarkar, Aniket; Rog, Tomasz; Bunker, Alex