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收藏分享 收藏 Discretizing multiple continuous predictors with U-shaped relationships with lnOR: introducing the recursive gradient scanning method in clinical and epidemiological research
Yang, Shuo; Su, Huaan; Zhang, Nanxiang; Han, Yuduan; Ge, Yingfeng; Fei, Yi; Liu, Ying; Hilowle, Abdullahi; Xu, Peng; Zhang, Jinxin 分享 收藏 The deacetylase SIRT6 reduces amyloid pathology and supports cognition in mice by reducing the stability of APP in neurons去乙酰化酶SIRT6通过降低神经元中APP的稳定性，减少小鼠的淀粉样蛋白病理并支持其认知能力。Cheng, Rong; Bai, Ning; Liu, Shuhui; Zhao, Xiong; Jiang, Bo; Guo, Wendong; Cao, Sunrun; Liu, Jingwei; Li, Na; Li, Xiaoman; Wu, Xuan; Yi, Fei; Wang, Zhuo; Guo, Qiqiang; Wei, Jiayi; Bai, Ming; Jiang, Xiaoyou; Song, Xiaoyu; Wang, Zhuo; Miao, Qi; Wang, Difei; Di, Yu; Liu, Hua; Cao, Liu 分享 收藏 ABLIM1, a novel ubiquitin E3 ligase, promotes growth and metastasis of colorectal cancer through targeting IĸBα ubiquitination and activating NF-ĸB signalingHe, Ying; Shi, Qian; Ling, Yuhang; Guo, Huihui; Fei, Yi; Wu, Ruoyu; Tang, Chengwu; Zhang, Xilin; Yao, Linhua 分享 收藏 De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivityLiu, Jingwei; Zhou, Tingting; Dong, Xiang; Guo, Qiqiang; Zheng, Lixia; Wang, Xiaoxun; Zhang, Naijin; Li, Danni; Ren, Ling; Yi, Fei; Zhang, Ying; Li, Ziwei; Wang, Xiwen; Deng, Chengsi; Li, Chunlu; Xu, Hongde; Guan, Yi; Li, Xiaoman; Yu, Yang; Guo, Wendong; Wang, Zhuo; Jiang, Bo; Wu, Xuan; Bai, Ning; Feng, Yanling; Ma, Mengtao; Kong, Qingquan; Wei, Jiayi; Wang, Zhenshuang; Li, Hao; Lu, Songming; Cao, Liangzi; Xiao, Yutong; Song, Xiaoyu; Wang, Zhenning; Xing, Chengzhong; Cao, Liu 分享 收藏 分享 收藏 分享 收藏 Progerin modulates the IGF-1R/Akt signaling involved in agingJiang, Bo; Wu, Xuan; Meng, Fang; Si, Limiao; Cao, Sunrun; Dong, Yuqing; Sun, Huayi; Lv, Mengzhu; Xu, Hongde; Bai, Ning; Guo, Qiqiang; Song, Xiaoyu; Yu, Yang; Guo, Wendong; Yi, Fei; Zhou, Tingting; Li, Xiaoman; Feng, Yanling; Wang, Zhuo; Zhang, Dan; Guan, Yi; Ma, Mengtao; Liu, Jingwei; Li, Xining; Zhao, Weidong; Liu, Baohua; Finkel, Toren; Cao, Liu 分享 收藏 Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic miceBai, Ning; Li, Na; Cheng, Rong; Guan, Yi; Zhao, Xiong; Song, Zhijie; Xu, Hongde; Yi, Fei; Jiang, Bo; Li, Xiaoman; Wu, Xuan; Jiang, Cui; Zhou, Tingting; Guo, Qiqiang; Guo, Wendong; Feng, Yanling; Wang, Zhuo; Ma, Mengtao; Yu, Yang; Wang, Zhanyou; Zhang, Shengping; Wang, Chuangui; Zhao, Weidong; Liu, Shihui; Song, Xiaoyu; Liu, Hua; Cao, Liu 分享 收藏 Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicingYuan, Baolei; Zhou, Xuan; Suzuki, Keiichiro; Ramos-Mandujano, Gerardo; Wang, Mengge; Tehseen, Muhammad; Cortes-Medina, Lorena, V; Moresco, James J.; Dunn, Sarah; Hernandez-Benitez, Reyna; Hishida, Tomoaki; Kim, Na Young; Andijani, Manal M.; Bi, Chongwei; Ku, Manching; Takahashi, Yuta; Xu, Jinna; Qiu, Jinsong; Huang, Ling; Benner, Christopher; Aizawa, Emi; Qu, Jing; Liu, Guang-Hui; Li, Zhongwei; Yi, Fei; Ghosheh, Yanal; Shao, Changwei; Shokhirev, Maxim; Comoli, Patrizia; Frassoni, Francesco; Yates, John R., III; Fu, Xiang-Dong; Esteban, Concepcion Rodriguez; Hamdan, Samir; Li, Mo; Belmonte, Juan Carlos Izpisua 分享 收藏 RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progressionZhou, Tingting; Wang, Shengli; Song, Xiaoyu; Liu, Wensu; Dong, Fang; Huo, Yunlong; Zou, Renlong; Wang, Chunyu; Zhang, Siyi; Liu, Wei; Sun, Ge; Lin, Lin; Zeng, Kai; Dong, Xiang; Guo, Qiqiang; Yi, Fei; Wang, Zhuo; Li, Xiaoman; Jiang, Bo; Cao, Liu; Zhao, Yue 分享 收藏 分享 收藏 The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesisYi, Fei; Zhang, Ying; Wang, Zhijun; Wang, Zhuo; Li, Ziwei; Zhou, Tingting; Xu, Hongde; Liu, Jingwei; Jiang, Bo; Li, Xiaoman; Wang, Liang; Bai, Ning; Guo, Qiqiang; Guan, Yi; Feng, Yanling; Mao, Zhiyong; Fan, Guangjian; Zhang, Shengping; Wang, Chuangui; Cao, Longyue; O'Rourke, Brian P.; Wang, Yang; Wu, Yanmei; Wu, Boquan; You, Shilong; Zhang, Naijin; Guan, Junlin; Song, Xiaoyu; Sun, Yingxian; Wei, Shi; Cao, Liu 分享 收藏 Accumulation of prelamin A induces premature aging through mTOR overactivationPan, Xumeng; Jiang, Bo; Wu, Xuan; Xu, Hongde; Cao, Sunrun; Bai, Ning; Li, Xiaoman; Yi, Fei; Guo, Qiqiang; Guo, Wendong; Song, Xiaoyu; Meng, Fang; Li, Xining; Liu, Yi; Cao, Liu 分享 收藏 ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress氧化应激下ATM-CHK2-Beclin 1轴促进自噬维持ROS稳态Guo, Qi-Qiang; Wang, Shan-Shan; Zhang, Shan-Shan; Xu, Hong-De; Li, Xiao-Man; Guan, Yi; Yi, Fei; Zhou, Ting-Ting; Jiang, Bo; Bai, Ning; Ma, Meng-Tao; Wang, Zhuo; Feng, Yan-Ling; Guo, Wen-Dong; Wu, Xuan; Zhao, Gui-Feng; Fan, Guang-Jian; Zhang, Sheng-Ping; Wang, Chuan-Gui; Cao, Long-Yue; O'Rourke, Brian P.; Liu, Shi-Hui; Wang, Ping-Yuan; Han, Shuai; Song, Xiao-Yu; Cao, Liu 分享 收藏 分享 收藏 SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylationZhang, Wenyu; Feng, Yanling; Guo, Qiqiang; Guo, Wendong; Xu, Hongde; Li, Xiaoman; Yi, Fei; Guan, Yi; Geng, Nanxi; Wang, Pingyuan; Cao, Longyue; O'Rourke, Brian P.; Jo, Juhyeon; Kwon, Jiyun; Wang, Ruihong; Song, Xiaoyu; Lee, In Hye; Cao, Liu 分享 收藏 分享 收藏 分享 收藏 
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