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A Framework for Genetic Logic Synthesis

delete2015-11-01
delete22
PRE
AI
P
Prashant Vaidyanathan *
B
Bryan S. Der
S
Swapnil Bhatia
N
Nicholas Roehner
R
Ryan Silva
C
Christopher A. Voigt
D
Douglas Densmore
DOI:10.1109/JPROC.2015.2443832delete
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摘要

摘要

En 中文
Digital electronic circuits have inspired synthetic biologists to program living cells with synthetic decision-making circuits by creating multilevel genetic logic gates. In both genetic and electronic circuits, logic synthesis translates an abstract functional description into a representation that can be physically implemented. However, inherent differences in genetic logic devices present new synthesis challenges. Here we provide a starting point for a growing set of biodesign automation tools to tackle this challenge in a unified way. This framework will enable direct comparison of new approaches, results that are transferable and standardized, and research into independent areas of the problem formulation with a clear path toward future integration.
Keyword:
Boolean
digital
genetic
logic
synthesis
synthetic biology
transcription
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期刊

Proceedings of the IEEE 封面图
Proceedings of the IEEE
IF:
25.9
论文数:
9.9K
被引数:
4.5W

机构

B
boston university
学者数:
3.8W
论文数: 3.2W
被引数: 67
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