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deepTools: a flexible platform for exploring deep-sequencing data

delete2014-05-05
delete2.2K
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OA
AI
F
Fidel Ramírez
F
Friederike Dündar
D
Diehl, Sarah
B
Björn Grüning
T
Thomas Manke *
DOI:10.1093/nar/gku365delete
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摘要

摘要

En 中文
We present a Galaxy based web server for processing and visualizing deeply sequenced data. The web server's core functionality consists of a suite of newly developed tools, called deepTools, that enable users with little bioinformatic background to explore the results of their sequencing experiments in a standardized setting. Users can upload pre-processed files with continuous data in standard formats and generate heatmaps and summary plots in a straight-forward, yet highly customizable manner. In addition, we offer several tools for the analysis of files containing aligned reads and enable efficient and reproducible generation of normalized coverage files. As a modular and open-source platform, deepTools can easily be expanded and customized to future demands and developments. The deepTools webserver is freely available at http://deeptools.ie-freiburg.mpg.de and is accompanied by extensive documentation and tutorials aimed at conveying the principles of deep-sequencing data analysis. The web server can be used without registration. deepTools can be installed locally either stand-alone or as part of Galaxy.
Keyword:
GALAXY
BIAS
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期刊

Nucleic Acids Research 封面图
Nucleic Acids Research
IF:
13.1
论文数:
3.6W
被引数:
29.0W

机构

U
University of Freiburg
学者数:
3.3W
论文数: 2.4W
被引数: 3.4W
M
Max Planck Society
学者数:
8.2W
论文数: 7.7W
被引数: 3.3W
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