logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回

Deterministic patterns in single-cell transcriptomic data

delete2025-01-11
delete0
delete
OA
AI
Z
Zhixing Cao *
Y
Yiling Wang
R
Ramon Grima *
DOI：10.1038/s41540-025-00490-5delete
delete原文链接
delete分享
delete收藏
查看原文
摘要

摘要

En 中文
We report the existence of deterministic patterns in statistical plots of single-cell transcriptomic data. We develop a theory showing that the patterns are neither artifacts introduced by the measurement process nor due to underlying biological mechanisms. Rather they naturally emerge from finite sample size effects. The theory precisely predicts the patterns in data from multiplexed error-robust fluorescence in situ hybridization and five different types of single-cell sequencing platforms.
Keyword:
GENE-EXPRESSION
RNA
AI总结

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

N
npj Systems Biology and Applications
IF:
3.5
论文数:
837
被引数:
1.3K

机构

U
University of Edinburgh
学者数:
5.2W
论文数: 4.6W
被引数: 71
引用论文

引用论文

Temporal changes in plasma levels and metabolism of ketone bodies by liver and brain after ethanol and/or starvation in C57BL/6J miceC57BL/6J小鼠乙醇和/或饥饿后血浆水平和肝脏和大脑中酮体代谢的时间变化
errDrug and Alcohol Dependence
IF0
err1984-03-01
err0
PREAI
errRobert A. Schreiber; Yu-Yan Yeh
err分享
err收藏
Early introduction of palliative care and advanced care planning for children with complex chronic medical conditions: a pilot study对患有复杂慢性疾病的儿童早期引入姑息治疗和高级护理计划: 一项初步研究
errChild: Care, Health and Development
IF0
err2016-03-29
err0
PREAI
errD. B. Liberman; E. Song; L. M. Radbill; P. K. Pham; S. F. Derrington
err分享
err收藏
The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian
errSCIENCE ADVANCES
IF12.5
err2023-08-11
err13
errOAAI
errWeidemann, Douglas E.; Holehouse, James; Singh, Abhyudai; Grima, Ramon; Hauf, Silke
err分享
err收藏
Current best practices in single-cell RNA-seq analysis: a tutorial单细胞rna-seq分析的当前最佳实践: 教程
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2019-06-19
err1.2K
errOAAI
errLuecken, Malte D.; Theis, Fabian J.
err分享
err收藏
Massively parallel digital transcriptional profiling of single cells单细胞的大规模并行数字转录谱分析
errNATURE COMMUNICATIONS
IF15.7
err2017-01-16
err2.9K
errOAAI
errZheng, Grace X. Y.; Terry, Jessica M.; Belgrader, Phillip; Ryvkin, Paul; Bent, Zachary W.; Wilson, Ryan; Ziraldo, Solongo B.; Wheeler, Tobias D.; McDermott, Geoff P.; Zhu, Junjie; Gregory, Mark T.; Shuga, Joe; Montesclaros, Luz; Underwood, Jason G.; Masquelier, Donald A.; Nishimura, Stefanie Y.; Schnall-Levin, Michael; Wyatt, Paul W.; Hindson, Christopher M.; Bharadwaj, Rajiv; Wong, Alexander; Ness, Kevin D.; Beppu, Lan W.; Deeg, H. Joachim; McFarland, Christopher; Loeb, Keith R.; Valente, William J.; Ericson, Nolan G.; Stevens, Emily A.; Radich, Jerald P.; Mikkelsen, Tarjei S.; Hindson, Benjamin J.; Bielas, Jason H.
err分享
err收藏
err
IF0
err
err0
errOAAI
err
err分享
err收藏
Validation of noise models for single-cell transcriptomics
errNATURE METHODS
IF32.1
err2014-04-20
err559
PREAI
errGrun, Dominic; Kester, Lennart; van Oudenaarden, Alexander
err分享
err收藏
Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments
errNATURE BIOTECHNOLOGY
IF41.7
err2013-07-21
err207
PREAI
errWills, Quin F.; Livak, Kenneth J.; Tipping, Alex J.; Enver, Tariq; Goldson, Andrew J.; Sexton, Darren W.; Holmes, Chris
err分享
err收藏
Towards the Automatic Evolution of Reengineering Tools
errNinth European Conference on Software Maintenance and Reengineering
IF0
err2024-09-06
err0
PREAI
errM. Di Penta; K. Taneja
err分享
err收藏
Comparative Analysis of Single-Cell RNA Sequencing Methods单细胞RNA测序方法的比较分析
errMOLECULAR CELL
IF16.6
err2017-02-01
err1.1K
errOAAI
errZiegenhain, Christoph; Vieth, Beate; Parekh, Swati; Reinius, Bjorn; Guillaumet-Adkins, Amy; Smets, Martha; Leonhardt, Heinrich; Heyn, Holger; Hellmann, Ines; Enard, Wolfgang
err分享
err收藏
学者 查看更多内容