.png){kind=icon}
返回
Engineered Tools to Study Intercellular Communication
.png){kind=icon}
OA
AI
DOI：10.1002/advs.202002825.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
All multicellular organisms rely on intercellular communication networks to coordinate physiological functions. As members of a dynamic social network, each cell receives, processes, and redistributes biological information to define and maintain tissue homeostasis. Uncovering the molecular programs underlying these processes is critical for prevention of disease and aging and development of therapeutics. The study of intercellular communication requires techniques that reduce the scale and complexity of in vivo biological networks while resolving the molecular heterogeneity in omic layers that contribute to cell state and function. Recent advances in microengineering and high-throughput genomics offer unprecedented spatiotemporal control over cellular interactions and the ability to study intercellular communication in a high-throughput and mechanistic manner. Herein, this review discusses how salient engineered approaches and sequencing techniques can be applied to understand collective cell behavior and tissue functions.
Keyword:
biomedical devices
cell– cell communication
high‐ throughput sequencing
intercellular communication
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
14.1
论文数:
1.8W
被引数:
11.5W
机构
暂无机构信息
引用论文
Occurrence of the potent mutagens 2-nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles在细小的空气传播颗粒中发生有效的诱变剂2-硝基苯并蒽酮和3-硝基苯并蒽酮.png)
SCIENTIFIC REPORTSOAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏Disorder, electron-electron interactions and the metal-insulator transition in heavily doped Si:P
PREAI
分享收藏Recent advances in microfluidic technologies for cell-to-cell interaction studiesLAB ON A CHIPOAAI
LAB ON A CHIPIF5.4
OAAI分享收藏Spatial organization of the somatosensory cortex revealed by osmFISHosmFISH揭示的体感皮层的空间组织NATURE METHODS
NATURE METHODSIF32.1
PREAI
分享收藏Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasisNATURE REVIEWS CANCER
NATURE REVIEWS CANCERIF66.8
PREAI
分享收藏CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexesCellPhoneDB: 从多亚基配体-受体复合物的联合表达推断细胞-细胞通讯NATURE PROTOCOLSOAAI
NATURE PROTOCOLSIF16
OAAI分享收藏
查看更多内容