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Functional patchworking at the plasma membrane
DOI:10.15252/embj.2018100144.png)
摘要
En 中文
Lipids and proteins are not evenly distributed within the plasma membrane (PM), but instead segregate laterally into many specialized microdomains whose functional relevance is not clear. In this issue, Busto et al (2018) demonstrate that substrate flux through a nutrient transporter drives the lateral relocation of the transporter between specific microdomains at the yeast PM, suggesting that regulating the lateral plasma membrane compartmentalization for individual proteins could be a general process for cellular response to environmental conditions.
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期刊
IF:
8.3
论文数:
1.3W
被引数:
6.3W
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引用论文
Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation
SCIENTIFIC REPORTS
IF3.9

