Sébastien Léon - Publications, H-index & Citations

Sébastien Léon

centre national de la recherche scientifique (cnrs)

27H指数

71论文数

2.6K被引数

收录论文 34

发表时间

A genetic screen reveals a key role for Reg1 in 2-deoxyglucose sensing and yeast AMPK inhibition 遗传筛选揭示了Reg1在2-脱氧葡萄糖感应和酵母AMPK抑制中的关键作用

PLOS GENETICS

IF3.7

2025-10-01

PREAI

Ballin, Alberto; Albanese, Veronique; Miled, Samia; Legros, Veronique; Chevreux, Guillaume; Verraes, Agathe; Friedrich, Anne; Leon, Sebastien

Ubiquiton-An inducible, linkage-specific polyubiquitylation tool

MOLECULAR CELL

IF16.6

2024-01-01

OAAI

Renz, Christian; Asimaki, Evrydiki; Meister, Cindy; Albanese, Veronique; Petriukov, Kirill; Krapoth, Nils C.; Wegmann, Sabrina; Wollscheid, Hans-Peter; Wong, Ronald P.; Fulzele, Amitkumar; Chen, Jia-Xuan; Leon, Sebastien; Ulrich, Helle D.

2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

PLOS GENETICS

IF3.7

2022-08-11

OAAI

laussel, Clotilde; Albanese, Veronique; Garcia-Rodriguez, Francisco Javier; Ballin, Alberto; Defenouillere, Quentin; Leon, Sebastien

Cellular toxicity of the metabolic inhibitor 2-deoxyglucose and associated resistance mechanisms 代谢抑制剂2-脱氧葡萄糖的细胞毒性及相关耐药机制

BIOCHEMICAL PHARMACOLOGY

IF5.6

2020-12-01

OAAI

Laussel, Clotilde; Leon, Sebastien

Sensitive detection of protein ubiquitylation using a protein fragment complementation assay (vol 133, jcs240093, 2020)

JOURNAL OF CELL SCIENCE

IF3.6

2020-08-12

OAAI

Le Boulch, Marie; Brossard, Audrey; Le Daz, Gaelle; Leon, Sebastien; Rabut, Gwenael

Complementary α-arrestin-ubiquitin ligase complexes control nutrient transporter endocytosis in response to amino acids

ELIFE

IF0

2020-08-03

OAAI

Ivashov, Vasyl; Zimmer, Johannes; Schwabl, Sinead; Kahlhofer, Jennifer; Weys, Sabine; Gstir, Ronald; Jakschitz, Thomas; Kremser, Leopold; Bonn, Gunther K.; Lindner, Herbert; Huber, Lukas A.; Leon, Sebastien; Schmidt, Oliver; Teis, David

Sensitive detection of protein ubiquitylation using a protein fragment complementation assay

JOURNAL OF CELL SCIENCE

IF3.6

2020-06-24

OAAI

Le Boulch, Marie; Brossard, Audrey; Le Dez, Gaelle; Leon, Sebastien; Rabut, Gwenael

Ubc13-Mms2 cooperates with a family of RING E3 proteins in budding yeast membrane protein sorting

JOURNAL OF CELL SCIENCE

IF3.6

2020-05-27

OAAI

Renz, Christian; Albanese, Veronique; Troester, Vera; Albert, Thomas K.; Santt, Olivier; Jacobs, Susan C.; Khmelinskii, Anton; Leon, Sebastien; Ulrich, Helle D.

The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose

SCIENCE SIGNALING

IF6.6

2019-09-03

OAAI

Defenouillere, Quentin; Verraes, Agathe; Laussel, Clotilde; Friedrich, Anne; Schacherer, Joseph; Leon, Sebastien

Functional patchworking at the plasma membrane

EMBO JOURNAL

IF8.3

2018-07-30

OAAI

Leon, Sebastien; Teis, David

Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms

SCIENCE ADVANCES

IF12.5

2018-05-04

OAAI

Kazamia, Elena; Sutak, Robert; Paz-Yepes, Javier; Dorrell, Richard G.; Vieira, Fabio Rocha Jimenez; Mach, Jan; Morrissey, Joe; Leon, Sebastien; Lam, France; Pelletier, Eric; Camadro, Jean-Michel; Bowler, Chris; Lesuisse, Emmanuel

The yeast arrestin-related protein Bul1 is a novel actor of glucose-induced endocytosis

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2018-05-01

OAAI

Hovsepian, Junie; Albanese, Veronique; Becuwe, Michel; Ivashov, Vasyl; Teis, David; Leon, Sebastien

Ubiquitination-dependent control of sexual differentiation in fission yeast

ELIFE

IF0

2017-08-25

OAAI

Simonetti, Fabrizio; Candelli, Tito; Leon, Sebastien; Libri, Domenico; Rougemaille, Mathieu

Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis

JOURNAL OF CELL BIOLOGY

IF6.4

2017-05-03

OAAI

Hovsepian, Junie; Defenouillere, Quentin; Albanese, Veronique; Vachova, Libuse; Garcia, Camille; Palkova, Zdena; Leon, Sebastien

Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2015-06-01

OAAI

Herrador, Antonio; Livas, Daniela; Soletto, Lucia; Becuwe, Michel; Leon, Sebastien; Vincent, Olivier

Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5

ELIFE

IF0

2014-11-07

OAAI

Becuwe, Michel; Leon, Sebastien

A Mechanism for Protein Monoubiquitination Dependent on a trans-Acting Ubiquitin-binding Domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-06-01

OAAI

Herrador, Antonio; Leon, Sebastien; Haguenauer-Tsapis, Rosine; Vincent, Olivier

Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-03-14

161

OAAI

Miermont, Agnes; Waharte, Francois; Hu, Shiqiong; McClean, Megan Nicole; Bottani, Samuel; Leon, Sebastien; Hersen, Pascal

A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2012-06-01

OAAI

Erpapazoglou, Zoi; Dhaoui, Manel; Pantazopoulou, Marina; Giordano, Francesca; Mari, Muriel; Leon, Sebastien; Raposo, Graca; Reggiori, Fulvio; Haguenauer-Tsapis, Rosine

A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis

JOURNAL OF CELL BIOLOGY

IF6.4

2012-01-16

124

OAAI

Becuwe, Michel; Vieira, Neide; Lara, David; Gomes-Rezende, Jessica; Soares-Cunha, Carina; Casal, Margarida; Haguenauer-Tsapis, Rosine; Vincent, Olivier; Paiva, Sandra; Leon, Sebastien

研究方向