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High-resolution single-photon imaging with physics-informed deep learning

delete2023-09-22
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边丽蘅 封面图
边丽蘅 (Liheng Bian) *
H
Haoze Song
L
Lintao Peng
X
Xuyang Chang
X
Xi Yang
R
Roarke Horstmeyer
叶林 封面图
叶林 (Lin Ye)
朱
朱春丽 (Chunli Zhu)
秦通 封面图
秦通 (Tong Qin)
郑
郑德智 (Dezhi Zheng)
张
张军 (Jun Zhang) *
DOI:10.1038/s41467-023-41597-9delete
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摘要

摘要

En 中文
High-resolution single-photon imaging remains a big challenge due to the complex hardware manufacturing craft and noise disturbances. Here, we introduce deep learning into SPAD, enabling super-resolution single-photon imaging with enhancement of bit depth and imaging quality. We first studied the complex photon flow model of SPAD electronics to accurately characterize multiple physical noise sources, and collected a real SPAD image dataset (64 x 32 pixels, 90 scenes, 10 different bit depths, 3 different illumination flux, 2790 images in total) to calibrate noise model parameters. With this physical noise model, we synthesized a large-scale realistic single-photon image dataset (image pairs of 5 different resolutions with maximum megapixels, 17250 scenes, 10 different bit depths, 3 different illumination flux, 2.6 million images in total) for subsequent network training. To tackle the severe super-resolution challenge of SPAD inputs with low bit depth, low resolution, and heavy noise, we further built a deep transformer network with a content-adaptive self-attention mechanism and gated fusion modules, which can dig global contextual features to remove multi-source noise and extract full-frequency details. We applied the technique in a series of experiments including microfluidic inspection, Fourier ptychography, and high-speed imaging. The experiments validate the technique's state-of-the-art super-resolution SPAD imaging performance. High-resolution single-photon imaging is challenging due to complex hardware and noise disturbances. Here, the authors realise simultaneous single-photon denoising and super-resolution enhancement by physics-informed deep learning, with a physical multi-source noise model, two single-photon image datasets, and a deep transformer network.
Keyword:
ROOM-TEMPERATURE
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期刊

Nature Communications 封面图
Nature Communications
IF:
15.7
论文数:
9.4W
被引数:
91.2W

机构

D
Duke University
学者数:
6.3W
论文数: 5.7W
被引数: 6.5W
B
beijing institute of technology
学者数:
5.5W
论文数: 4.0W
被引数: 63
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