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Image Data Resource: a bioimage data integration and publication platform
DOI:10.1038/NMETH.4326.png)
摘要
En 中文
Access to primary research data is vital for the advancement of science. To extend the data types supported by community repositories, we built a prototype Image Data Resource (IDR). IDR links data from several imaging modalities, including high-content screening, multi-dimensional microscopy and digital pathology, with public genetic or chemical databases and cell and tissue phenotypes expressed using controlled ontologies. Using this integration, IDR facilitates the analysis of gene networks and reveals functional interactions that are inaccessible to individual studies. To enable reanalysis, we also established a computational resource based on Jupyter notebooks that allows remote access to the entire IDR. IDR is also an open-source platform for publishing imaging data. Thus IDR provides an online resource and a software infrastructure that promotes and extends publication and reanalysis of scientific image data.
Keyword:
CARBONIC-ANHYDRASE-IV
GENOME-WIDE RNAI
SUBCELLULAR-LOCALIZATION
GENE-EXPRESSION
CELL-DIVISION
MICROSCOPY
REVEALS
ATLAS
REPOSITORY
MANAGEMENT
AI总结
对已上传原文的论文进行重点信息的提取,主要内容包括:简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
32.1
论文数:
7.2K
被引数:
12.7W
机构
引用论文
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
NATURE CELL BIOLOGY
IF19.1
A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly敏化的RNAi筛选揭示了纺锤体组装所需的ch-tog遗传相互作用网络
SCIENTIFIC REPORTS
IF3.9

