.png){kind=icon}
返回
Milestones in directed enzyme evolution
.png){kind=icon}
PRE
AI
DOI：10.1016/S1367-5931(02)00396-4.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Directed evolution has now been used for over two decades as an alternative to rational design for protein engineering. Protein function, however, is complex, and modifying enzyme activity is a tall order. We can now improve existing enzyme activity, change enzyme selectivity and evolve function de novo using directed evolution. Although directed evolution is now used routinely to improve existing enzyme activity, there are still only a handful of examples where substrate selectivity has been modified sufficiently for practical application, and the de novo evolution of function largely eludes us.
Keyword:
RED FLUORESCENT PROTEIN
PHAGE DISPLAY
RANDOM MUTAGENESIS
ESCHERICHIA-COLI
SITE-SPECIFICITY
CRE RECOMBINASE
GENETIC-CODE
SELECTION
LIBRARY
CATALYSIS
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
6.1
论文数:
3.1K
被引数:
1.1W
机构
暂无机构信息
引用论文
分享收藏
Relationship of Flag Leaf Characteristics to Economically Important Traits in Two Spring Wheat Crosses.png)
Crop Science
Crop ScienceIF0
PREAI
分享收藏
查看更多内容