.png){kind=icon}
返回
Next-generation interfaces for studying neural function
.png){kind=icon}
OA
AI
DOI：10.1038/s41587-019-0198-8.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Monitoring and modulating the diversity of signals used by neurons and glia in a closed-loop fashion is necessary to establish causative links between biochemical processes within the nervous system and observed behaviors. As developments in neural-interface hardware strive to keep pace with rapid progress in genetically encoded and synthetic reporters and modulators of neural activity, the integration of multiple functional features becomes a key requirement and a pressing challenge in the field of neural engineering. Electrical, optical and chemical approaches have been used to manipulate and record neuronal activity in vivo, with a recent focus on technologies that both integrate multiple modes of interaction with neurons into a single device and enable bidirectional communication with neural circuits with enhanced spatiotemporal precision. These technologies not only are facilitating a greater understanding of the brain, spinal cord and peripheral circuits in the context of health and disease, but also are informing the development of future closed-loop therapies for neurological, neuro-immune and neuroendocrine conditions.
Keyword:
MICROELECTRODE ARRAY
TEMPORAL RESOLUTION
OPTOGENETIC CONTROL
DOPAMINE DETECTION
TRAINING SETS
BRAIN
DYNAMICS
MICRODIALYSIS
PROBES
STIMULATION
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
41.7
论文数:
1.2W
被引数:
11.5W
机构
暂无机构信息
引用论文
分享收藏
A light- and calcium-gated transcription factor for imaging and manipulating activated neurons.png)
NATURE BIOTECHNOLOGYOAAI
NATURE BIOTECHNOLOGYIF41.7
OAAI分享收藏Chronic microsensors for longitudinal, subsecond dopamine detection in behaving animalsNATURE METHODSOAAI
NATURE METHODSIF32.1
OAAI分享收藏
查看更多内容