.png){kind=icon}
返回
Phase imaging through a single multimode fiber
.png){kind=icon}
PRE
AI
DOI：10.1364/OL.527588.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Phase imaging techniques are pivotal for achieving high- contrast visualization of unstained biological specimens in vitro, which is typically not applicable in narrow spaces. Recently, multimode fiber (MMF) has shown promise in enabling high-resolution in vivo endoscopy in biological research. Herein, we introduce a novel, to the best of our knowledge, phase imaging microscopy technique employing a single multimode fiber, showcasing remarkable capabilities in high-contrast imaging and quantitative shape reconstruction through frequency-domain modulation. Our method, validated through comparisons with reflection and phase- contrast results, demonstrates exceptional ability in imaging diverse samples, including microspheres, semiconductor chips, and oral epithelial cells. Notably, the quantitative reconstruction of surface shape achieves a sensitivity of less than 100 nm, enabling the extraction of three-dimensional information from single focal plane images. Moreover, our technique excels in contrast enhancement and defocused background suppression, presenting a promising avenue for minimally invasive, high-contrast, label-free in vivo phase imaging. (c) 2024 Optica Publishing Group
Keyword:
MICROSCOPY
ENDOSCOPY
期刊
IF:
3.3
论文数:
4.0W
被引数:
7.6W
机构
引用论文
分享收藏分享收藏Refractive index tomograms and dynamic membrane fluctuations of red blood cells from patients with diabetes mellitus.png)
SCIENTIFIC REPORTS
OAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏Association of Histone Methyltransferase G9a and Overall Survival After Liver Resection of Patients With Hepatocellular Carcinoma With a Median Observation of 40 Months组蛋白甲基转移酶G9a与肝细胞癌患者肝切除术后总生存期的关系，中位观察时间为40个月MedicineOAAI
MedicineIF0
OAAI分享收藏
查看更多内容