Probing ligand selectivity in pathogens

doi:10.7554/eLife.94720

2023-12-21

Bryan VanSchouwen

Giuseppe Melacini *

DOI：10.7554/eLife.94720

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摘要

En 中文

Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?

Keyword:

Protein kinase A

ligand selectivity

trypanosomatid pathogens

T. brucei

T. cruzi

L. donovani

Other

期刊

eLife

IF:

论文数:

1.8W

被引数:

机构

McMaster University

学者数:

3.6W

论文数: 3.3W

被引数: 4.4W

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