Bryan VanSchouwen - Publications, H-index & Citations

Bryan VanSchouwen

McMaster University

14H指数

49论文数

1.0K被引数

收录论文 24

发表时间

Activating PRKG1 Variant Enhances Smooth Muscle Cell Deformability To Cause Aortopathy 激活PRKG1变体增强平滑肌细胞变形能力导致主动脉病

jacc: basic to translational science

IF0

2026-01-15

OAAI

Marie E. Jost; Moyra Schweizer; Philipp Henning; Christian Gorzelanny; Moritz Lehners; Bernhard Ellinger; Javier Boix-Campos; Johan-Moritz Kux; Shubhangi Singh; Alexandra Fachinger; Karla Martinez Pomier; Bryan VanSchouwen; Anja M. Billing; Doreen Biedenweg; Michaela Schweizer; Saskia Siegel; Rudolph Reimer; Mona Brandt; Laura Priesmeier; Ulrike Fuchs

Probing ligand selectivity in pathogens

ELIFE

IF0

2023-12-21

OAAI

VanSchouwen, Bryan; Melacini, Giuseppe

Fractionation factors reveal hidden frustration in an ancient allosteric module

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2023-03-28

OAAI

VanSchouwen, Bryan; Della Libera, Leonardo; Melacini, Giuseppe

An auto-inhibited state of protein kinase G and implications for selective activation 蛋白激酶G的自动抑制状态及其对选择性激活的影响

ELIFE

IF0

2022-08-05

OAAI

Sharma, Rajesh; Kim, Jeong Joo; Qin, Liying; Henning, Philipp; Akimoto, Madoka; VanSchouwen, Bryan; Kaur, Gundeep; Sankaran, Banumathi; MacKenzie, Kevin R.; Melacini, Giuseppe; Casteel, Darren E.; Herberg, Friedrich W.; Kim, Choel

Identification of core allosteric sites through temperature- and nucleus-invariant chemical shift covariance

BIOPHYSICAL JOURNAL

IF3.1

2022-06-01

OAAI

Mohamed, Hebatallah; Baryar, Ubaidullah; Bashiri, Amir; Selvaratnam, Rajeevan; VanSchouwen, Bryan; Melacini, Giuseppe

State-selective frustration as a key driver of allosteric pluripotency

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Byun, Jung Ah; VanSchouwen, Bryan; Parikh, Nishi; Akimoto, Madoka; McNicholl, Eric Tyler; Melacini, Giuseppe

Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding

BIOPHYSICAL JOURNAL

IF3.1

2020-09-01

OAAI

Boulton, Stephen; Van, Katherine; VanSchouwen, Bryan; Augustine, Jerry; Akimoto, Madoka; Melacini, Giuseppe

Allosteric pluripotency as revealed by protein kinase A

SCIENCE ADVANCES

IF12.5

2020-06-17

OAAI

Byun, J. A.; Akimoto, M.; VanSchouwen, B.; Lazarou, T. S.; Taylor, S. S.; Melacini, G.

The structure of the apo cAMP-binding domain of HCN4-a stepping stone toward understanding the cAMP-dependent modulation of the hyperpolarization-activated cyclic-nucleotide-gated ion channels

FEBS JOURNAL

IF4.2

2018-03-14

OAAI

Akimoto, Madoka; VanSchouwen, Bryan; Melacini, Giuseppe

Molecular Mechanism for the (-)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2017-08-25

PREAI

Ahmed, Rashik; VanSchouwen, Bryan; Jafari, Naeimeh; Ni, Xiaodan; Ortega, Joaquin; Melacini, Giuseppe

Crystal structure of cGMP-dependent protein kinase Iβ cyclic nucleotide-binding-B domain : Rp-cGMPS complex reveals an apo-like, inactive conformation cGMP依赖性蛋白激酶i β 环核苷酸结合B结构域的晶体结构: rp-cgmps复合物揭示了类似apo的非活性构象

FEBS LETTERS

IF3

2016-12-23

OAAI

Campbell, James C.; VanSchouwen, Bryan; Lorenz, Robin; Sankaran, Banumathi; Herberg, Friedrich W.; Melacini, Giuseppe; Kim, Choel

Cracking the allosteric code of NMR chemical shifts

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-08-10

OAAI

VanSchouwen, Bryan; Melacini, Giuseppe

Mechanism of Cyclic AMP Partial Agonism in Protein Kinase G (PKG)

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

VanSchouwen, Bryan; Selvaratnam, Rajeevan; Giri, Rajanish; Lorenz, Robin; Herberg, Friedrich W.; Kim, Choel; Melacini, Giuseppe

Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-11-01

OAAI

VanSchouwen, Bryan; Selvaratnam, Rajeevan; Giri, Rajanish; Lorenz, Robin; Herberg, Friedrich W.; Kim, Choel; Melacini, Giuseppe

Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-07-01

OAAI

VanSchouwen, Bryan; Akimoto, Madoka; Sayadi, Maryam; Fogolari, Federico; Melacini, Giuseppe

A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-08-01

OAAI

Akimoto, Madoka; Zhang, Zaiyong; Boulton, Stephen; Selvaratnam, Rajeevan; VanSchouwen, Bryan; Gloyd, Melanie; Accili, Eric A.; Lange, Oliver F.; Melacini, Giuseppe

Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR 挖掘cAMP信号的翻译潜力: NMR揭示的cAMP激动和拮抗选择性的分子基础

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2014-03-20

PREAI

Boulton, Stephen; Akimoto, Madoka; VanSchouwen, Bryan; Moleschi, Kody; Selvaratnam, Rajeevan; Giri, Rajanish; Melacini, Giuseppe

Allosteric linkers in cAMP signalling

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2014-01-23

OAAI

Akimoto, Madoka; Moleschi, Kody; Boulton, Stephen; VanSchouwen, Bryan; Selvaratnam, Rajeevan; Taylor, Susan S.; Melacini, Giuseppe