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The selfishly selfless placenta
DOI:10.1172/JCI134272.png)
摘要
En 中文
Although iron deficiency continues to pose a problem for pregnant women and fetal development, an incomplete understanding of placental adaptation to limited iron availability has hindered efforts to identify optimal supplementation strategies. In this issue of the JCI, Sangkhae et al. used mouse models and human placentas to explore maternal, placental, and fetal responses to alterations in iron status during pregnancy. The authors identified molecular mechanisms that limit placental ability to upregulate iron transport in the setting of severe iron deficiency and explored a potential marker of placental maladaptation.
Keyword:
IRON STATUS
FETAL
HEPCIDIN
HEALTH
期刊
IF:
13.6
论文数:
1.5W
被引数:
11.5W
机构
引用论文
Impact of maternal and neonatal iron status on placental transferrin receptor expression in pregnant adolescents
PLACENTA
IF2.5
Iron Supplementation during Pregnancy and Infancy: Uncertainties and Implications for Research and Policy
NUTRIENTS
IF5

