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TreeFam:: 2008 update

delete2007-12-23
delete295
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OA
AI
J
Jue Ruan
H
Heng Li
Z
Zhongzhong Chen
A
Avril Coghlan
L
Lachlan Coin
G
Guo, Yiran
J
Jean-Karim Hèriché
H
Hu, Yafeng
K
Karsten Kristiansen
L
Li, Ruiqiang
L
Liu, Tao
M
Moses, Alan
J
Junjie Qin
S
Søren Vang
A
Albert J. Vilella
U
Ureta-Vidal, Abel
B
Bolund, Lars
W
Wang, Jun
R
Richard Durbin *
DOI:10.1093/nar/gkm1005delete
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Abstract

Abstract

En 中文
TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains curated trees for 1314 families and automatically generated trees for another 14 351 families. We have expanded TreeFam to include 25 fully sequenced animal genomes, as well as four genomes from plant and fungal outgroup species. We have also introduced more accurate approaches for automatically grouping genes into families, for building phylogenetic trees, and for inferring orthologues and paralogues. The user interface for viewing phylogenetic trees and family information has been improved. Furthermore, a new perl API lets users easily extract data from the TreeFam mysql database.
Keywords:
PHYLOGENETIC TREES
DATABASE
GENOME
ORTHOLOGS
SEQUENCE
RESOURCE
INFORMATION
PARALOGS
AI Summary

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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Nucleic Acids Research cover
Nucleic Acids Research
IF:
13.1
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3.6W
Citations:
29.0W

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B
beijing institute of genomics, cas
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Aarhus University
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University of Southern Denmark
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wellcome trust sanger institute
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chinese academy of sciences
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