arrow
Return

A method for comparing multiple imputation techniques: A case study on the US national COVID cohort collaborative

delete2023-03-01
delete11
delete
OA
AI
E
Elena Casiraghi *
R
Rachel Wong *
M
Margaret Hall
B
Ben Coleman
M
Marco Notaro
M
Michael D. Evans
J
Jena Shaw Tronieri
H
Hannah Blau
B
Bryan Laraway
T
Tiffany J. Callahan
L
Lauren Chan
C
Carolyn T. Bramante
J
John B. Buse
R
Richard A. Moffitt
T
Til Stürmer‎
S
Steve Johnson
Y
Yu Raymond Shao
J
Justin Reese
P
Peter N. Robinson
A
Alberto Paccanaro
G
Giorgio Valentini
J
Jared D. Huling
K
Kenneth J. Wilkins
DOI:10.1016/j.jbi.2023.104295delete
deleteOriginal
deleteShare
deleteSave
View PDF
Abstract

Abstract

En 中文
Healthcare datasets obtained from Electronic Health Records have proven to be extremely useful for assessing associations between patients' predictors and outcomes of interest. However, these datasets often suffer from missing values in a high proportion of cases, whose removal may introduce severe bias. Several multiple imputation algorithms have been proposed to attempt to recover the missing information under an assumed missingness mechanism. Each algorithm presents strengths and weaknesses, and there is currently no consensus on which multiple imputation algorithm works best in a given scenario. Furthermore, the selection of each algorithm's parameters and data-related modeling choices are also both crucial and challenging.
Keywords:
Multiple Imputation
Evaluation framework
Clinical informatics
Diabetic patients
COVID-19 severity assessment
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Journal of Biomedical Informatics cover
Journal of Biomedical Informatics
IF:
4.5
Papers:
3.5K
Citations:
1.9W

Organization

University of Colorado System cover
University of Colorado System
Scholars:
6.2W
Papers: 5.5W
Citations: 1.8K
S
stony brook university
Scholars:
1.3W
Papers: 1.0W
Citations: 20
S
state university of new york (suny) system
Scholars:
6.4W
Papers: 5.7W
Citations: 65
U
university of north carolina
Scholars:
7.4W
Papers: 6.5W
Citations: 93
U
University of Minnesota Twin Cities
Scholars:
3.7W
Papers: 3.1W
Citations: 58
U
university of pennsylvania
Scholars:
9.2W
Papers: 7.8W
Citations: 153
U
university of colorado anschutz medical campus
Scholars:
2.3W
Papers: 1.7W
Citations: 22
L
Lawrence Berkeley National Laboratory
Scholars:
1.5W
Papers: 1.1W
Citations: 6.1W
U
University of North Carolina School of Medicine
Scholars:
1.6W
Papers: 1.0W
Citations: 20
U
University of Connecticut
Scholars:
2.4W
Papers: 2.1W
Citations: 2.5W
U
University of North Carolina Chapel Hill
Scholars:
3.8W
Papers: 3.0W
Citations: 46
U
University of Milan
Scholars:
5.0W
Papers: 3.9W
Citations: 5.0W
researcher View more organizations