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Community standards for open cell migration data

delete2020-05-12
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OA
AI
A
Alejandra González-Beltrán
P
Paola Masuzzo
C
Christophe Ampè
G
Gert‐Jan Bakker
S
Sébastien Besson
R
Robert H. Eibl
P
Peter Friedl
M
Matthias Gunzer
M
Mark Kittisopikul
S
Sylvia E. Le Dévédec
S
Simone Leo
J
Josh Moore
Y
Yael Paran
J
Jaime Prilusky
P
Philippe Rocca‐Serra
P
Philippe Roudot
M
Marc Schuster
G
Gwendolien Sergeant
S
Staffan Strömblad
J
Jason R. Swedlow
M
Merijn van Erp
M
Marleen Van Troys
A
Assaf Zaritsky
S
Susanna‐Assunta Sansone *
L
Lennart Martens *
DOI:10.1093/gigascience/giaa041delete
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Abstract

Abstract

En 中文
Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration.
Keywords:
cell migration
data standards
metadata
CMSO
MIACME
biotracks
frictionless data package
FAIR data
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