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Sylvia E. Le Dévédec

leiden university

28H-index
133Paper Count
2.8KCitation Count
Published Papers 57
Publication Date
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Imaging-Guided Live Single-Cell Lipid Profiling of Leader and Follower Cellsduring Collective Migration of Triple-Negative Breast Cancer Cells
errAdvanced Science
IF14.1
err2026-06-16
err0
errOAAI
errXiaoyue Huang; Judit González Riera; Mai Nguyen; Jeremy Broekhuis; Sylvia E. Le Dévédec; Ahmed Ali; Thomas Hankemeier
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Decoding SR protein regulation: kinases, phosphatases, and therapeutic targeting strategies
errCellular Oncology
IF4.8
err2026-02-04
err0
errOAAI
errNasi Liu; Fleur van der Ende; Bob van de Water; Sylvia E. Le Dévédec
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Visualizing the Invisible: Dual Click Imaging of Ruthenium-Based Photoactivated Chemotherapy Agents and Their DNA Synthesis Inhibition in Fixed Cancer Cells
errJournal of the American Chemical Society
IF15.6
err2025-11-05
err0
errOAAI
errAnja Busemann; Lisa Rieger; Rachael M. Cunningham; Sam C. Davidse; Irene Regeni; Ingrid Flaspohler; Claudia Schmidt; Xue-Quan Zhou; Vincent van Rixel; Maxime A. Siegler; Ingo Ott; Sylvia E. Le Dévédec; Hans-Achim Wagenknecht; Victoria J. DeRose; Sylvestre Bonnet
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Single-cell Raman and mass spectrometry analysis to probe cellular heterogeneity in tamoxifen uptake and metabolism
errAnalytical and Bioanalytical Chemistry
IF3.8
err2025-08-14
err0
errOAAI
errCongrou Zhang; Yasmine Abouleila; Sylvia Le Dévédec; Thomas Hankemeier; Arno Germond; Ahmed Ali
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errSave
Distinct lipidomic profiles in breast cancer cell lines relate to proliferation and EMT phenotypes
errbiochimica et biophysica acta molecular and cell biology of lipids
IF0
err2025-08-05
err0
PREAI
errHanneke Leegwater; Zhengzheng Zhang; Xiaobing Zhang; Xuesong Wang; Thomas Hankemeier; Annelien J.M. Zweemer; Bob van de Water; Erik Danen; Menno Hoekstra; Amy C. Harms; Alida Kindt; Sylvia E. Le Dévédec
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Lipid dysregulation in triple negative breast cancer: Insights from mass spectrometry-based approaches
errPROGRESS IN LIPID RESEARCH
IF14.9
err2025-04-01
err1
PREAI
errXiaoyue Huang; Ahmed Ali; Dounia E.I. Yachioui; Sylvia E. Le Dévédec; Thomas Hankemeier
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Lipidomic profiling of triple-negative breast cancer cells reveals distinct metabolic signatures associated with EpCAM expression
errTALANTA
IF6.1
err2025-02-01
err0
PREAI
errHuang, Xiaoyue; Di, Xinyu; Zuiderwijk, Melissa Celine; Zhang, Lu; Leegwater, Hanneke; Davidse, Sam; Kindt, Alida; Harms, Amy; Hankemeier, Thomas; Le Devedec, Sylvia E.; Ali, Ahmed
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Oxygen-Dependent Interactions between the Ruthenium Cage and the Photoreleased Inhibitor in NAMPT-Targeted Photoactivated Chemotherapy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-06-26
err0
errOAAI
errAbyar, Selda; Huang, Luojiao; Husiev, Yurii; Bretin, Ludovic; Chau, Bobby; Ramu, Vadde; Wildeman, Jacob Hendricus; Belfor, Kimberley; Wijaya, Lukas S.; van der Noord, Vera E.; Harms, Amy C.; Siegler, Maxime A.; Le Devedec, Sylvia E.; Bonnet, Sylvestre
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Lactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts
errANGIOGENESIS
IF9.2
err2024-06-06
err2
errOAAI
errYin, Jie; Forn-Cuni, Gabriel; Surendran, Akshaya Mahalakshmi; Lopes-Bastos, Bruno; Pouliopoulou, Niki; Jager, Martine J.; Le Devedec, Sylvia E.; Chen, Quanchi; Snaar-Jagalska, B. Ewa
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Cell viability imaging in tumor spheroids via DNA binding of a ruthenium(ii) light-switch complex
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err2
errOAAI
errRamu, Vadde; Wijaya, Lukas S.; Beztsinna, Nataliia; van de Griend, Corjan; van de Water, Bob; Bonnet, Sylvestre; Le Devedec, Sylvia E.
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Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-12-20
err10
errOAAI
errBretin, Ludovic; Husiev, Yurii; Ramu, Vadde; Zhang, Liyan; Hakkennes, Matthijs; Abyar, Selda; Johns, Andrew C.; Le Devedec, Sylvia E.; Betancourt, Tania; Kornienko, Alexander; Bonnet, Sylvestre
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A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury
errTOXICOLOGICAL SCIENCES
IF4.1
err2023-11-28
err4
errOAAI
errWijaya, Lukas S.; Gabor, Attila; Pot, Iris E.; van de Have, Luca; Saez-Rodriguez, Julio; Stevens, James L.; Le Devedec, Sylvia E.; Callegaro, Giulia; van de Water, Bob
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Community-developed checklists for publishing images and image analyses
errNATURE METHODS
IF32.1
err2023-09-14
err19
errOAAI
errSchmied, Christopher; Nelson, Michael S.; Avilov, Sergiy; Bakker, Gert-Jan; Bertocchi, Cristina; Bischof, Johanna; Boehm, Ulrike; Brocher, Jan; Carvalho, Mariana T.; Chiritescu, Catalin; Christopher, Jana; Cimini, Beth A.; Conde-Sousa, Eduardo; Ebner, Michael; Ecker, Rupert; Eliceiri, Kevin; Fernandez-Rodriguez, Julia; Gaudreault, Nathalie; Gelman, Laurent; Grunwald, David; Gu, Tingting; Halidi, Nadia; Hammer, Mathias; Hartley, Matthew; Held, Marie; Jug, Florian; Kapoor, Varun; Koksoy, Ayse Aslihan; Lacoste, Judith; Le Devedec, Sylvia; Le Guyader, Sylvie; Liu, Penghuan; Martins, Gabriel G.; Mathur, Aastha; Miura, Kota; Montero Llopis, Paula; Nitschke, Roland; North, Alison; Parslow, Adam C.; Payne-Dwyer, Alex; Plantard, Laure; Ali, Rizwan; Schroth-Diez, Britta; Schuetz, Lucas; Scott, Ryan T.; Seitz, Arne; Selchow, Olaf; Sharma, Ved P.; Spitaler, Martin; Srinivasan, Sathya; Strambio-De-Castillia, Caterina; Taatjes, Douglas; Tischer, Christian; Jambor, Helena Klara
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Development of an Affinity-Based Probe to Profile Endogenous Human Adenosine A3 Receptor Expression
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-02
err3
errOAAI
errBeerkens, Bert L. H.; Snijders, Inge M.; Snoeck, Joep; Liu, Rongfang; Tool, Anton T. J.; Le Devedec, Sylvia E.; Jespers, Willem; Kuijpers, Taco W.; van Westen, Gerard J. P.; Heitman, Laura H.; IJzerman, Adriaan P.; van der Es, Daan
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Single-cell metabolomics by mass spectrometry: ready for primetime?
errCURRENT OPINION IN BIOTECHNOLOGY
IF7
err2023-08-01
err9
errOAAI
errZhang, Congrou; Devedec, Sylvia E. Le; Ali, Ahmed; Hankemeier, Thomas
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Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-06-28
err36
errOAAI
errZhang, Liyan; Wang, Peiyuan; Zhou, Xue-Quan; Bretin, Ludovic; Zeng, Xiaolong; Husiev, Yurii; Polanco, Ehider A.; Zhao, Gangyin; Wijaya, Lukas S.; Biver, Tarita; Le Devedec, Sylvia E.; Sun, Wen; Bonnet, Sylvestre
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Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors
errBREAST CANCER RESEARCH
IF5.6
err2023-05-05
err5
errOAAI
errvan der Noord, Vera E.; van der Stel, Wanda; Louwerens, Gijs; Verhoeven, Danielle; Kuiken, Hendrik J.; Lieftink, Cor; Grandits, Melanie; Ecker, Gerhard F.; Beijersbergen, Roderick L.; Bouwman, Peter; Le Devedec, Sylvia E.; van de Water, Bob
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Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2023-02-24
err1
errOAAI
errLiu, Qiuyu; Liu, Nasi; van der Noord, Vera; van der Stel, Wanda; van de Water, Bob; Danen, Erik H. J.; Le Devedec, Sylvia E.
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A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A1 Receptor Using an Electrophilic Covalent Probe
errACS CHEMICAL BIOLOGY
IF3.8
err2022-10-24
err12
errOAAI
errBeerkens, Bert L. H.; Koc, Cagla; Liu, Rongfang; Florea, Bogdan I.; Devedec, Sylvia E. Le; Heitman, Laura H.; IJzerman, Adriaan P.; Van Der Es, Daan
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High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitors
errCELL BIOLOGY AND TOXICOLOGY
IF5.9
err2022-05-04
err8
errOAAI
errvan der Stel, Wanda; Yang, Huan; le Devedec, Sylvia E.; van de Water, Bob; Beltman, Joost B.; Danen, Erik H. J.
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Research Directions

No research directions
Co-authors
Cooperation Journals
P
Peter ten Dijke
H-index: 147 · Papers: 794
B
Benjamin G. Neel
H-index: 120 · Papers: 605
B
Benjamin Geiger
H-index: 112 · Papers: 449
J
John A. Foekens
H-index: 107 · Papers: 845
T
Taco W. Kuijpers
H-index: 103 · Papers: 833
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