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Efficiency landscape of bioorthogonal click reactions producing bispecific antibody conjugates
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DOI：10.1016/j.crmeth.2026.101416.png)
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Abstract
En 中文
• Systematic analysis of two chemical approaches for bispecific antibody production • Design of experiments framework for reaction parameters • Modular and rapid method that relies exclusively on off-the-shelf reagents
Keywords:
bioorthogonal chemistry
click chemistry
antibody
bioconjugation
bispecific antibody
reaction optimization
CP: biotechnology
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