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Light-triggered cardiac microphysiological model
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DOI：10.1063/5.0143409.png)
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Abstract
En 中文
Light is recognized as an accurate and noninvasive tool for stimulating excitable cells. Here, we report on a non-genetic approach based on organic molecular phototransducers that allows wiring- and electrode-free tissue modulation. As a proof of concept, we show photostimulation of an in vitro cardiac microphysiological model mediated by an amphiphilic azobenzene compound that preferentially dwells in the cell membrane. Exploiting this optical based stimulation technology could be a disruptive approach for highly resolved cardiac tissue stimulation.
Keywords:
OPTOGENETIC CONTROL
THIN-FILMS
MUSCLE
TISSUE
STIMULATION
MODULATION
ROBOTICS
NERVE
Journal
IF:
4.1
Papers:
491
Citations:
1.7K
Organization
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