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Spatially resolved transcriptomics in neuroscience

delete2021-01-06
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AI
J
Jennie Close
B
Brian Long
H
Hongkui Zeng *
DOI:10.1038/s41592-020-01040-zdelete
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Abstract

Abstract

En 中文
One major challenge in neuroscience is to gain a systematic understanding of the extraordinary diversity of brain cell types and how they contribute to brain function. Spatially resolved transcriptomics holds unmatched promise in unraveling the organization of brain cell types and their relationship with connectivity, circuit dynamics, behavior and disease. Here we discuss neuroscience applications of various spatially resolved transcriptomics methods, as well as technical challenges that need to be overcome to realize their full potentials.
Keywords:
CELL-TYPES
RNA
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Journal

Nature Methods cover
Nature Methods
IF:
32.1
Papers:
7.2K
Citations:
12.7W

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Allen Institute for Brain Science
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