arrow
Return

WormBase in 2022-data, processes, and tools for analyzing Caenorhabditis elegans

delete2022-02-04
delete164
delete
OA
AI
P
Paul A. Davis
M
Magdalena Zarowiecki
V
Valerio Arnaboldi
A
Andrés Becerra
S
Scott Cain
J
Juancarlos Chan
W
Wen J. Chen
J
Jaehyoung Cho
E
Eduardo da Veiga Beltrame
S
Stavros Diamantakis
S
Sibyl Gao
D
Dionysios Grigoriadis
C
Christian A Grove
T
Todd Harris
R
Ranjana Kishore
T
Tuan Anh Le
R
Raymond Lee
M
Manuel Luypaert
H
Hans‐Michael Müller
C
Cecilia Nakamura
P
Paulo Nuin
M
Michael Paulini
M
Mark Quinton-Tulloch
D
Daniela Raciti
F
Faye H. Rodgers
M
Matthew Russell
G
Gary Schindelman
A
Archana Singh
T
Tim Stickland
K
Kimberly Van Auken
Q
Qinghua Wang
G
Gary W. Williams
A
A. Jordan Wright
K
Karen Yook
B
Berriman, Matt
K
Kevin Howe
T
Tim Schedl
L
Lincoln Stein
P
Paul W. Sternberg *
DOI:10.1093/genetics/iyac003delete
deleteOriginal
deleteShare
deleteSave
View PDF
Abstract

Abstract

En 中文
WormBase (www.wormbase.org) is the central repository for the genetics and genomics of the nematode Caenorhabditis elegans. We provide the research community with data and tools to facilitate the use of C. elegans and related nematodes as model organisms for studying human health, development, and many aspects of fundamental biology. Throughout our 22-year history, we have continued to evolve to reflect progress and innovation in the science and technologies involved in the study of C. elegans. We strive to incorporate new data types and richer data sets, and to provide integrated displays and services that avail the knowledge generated by the published nematode genetics literature. Here, we provide a broad overview of the current state of WormBase in terms of data type, curation workflows, analysis, and tools, including exciting new advances for analysis of single-cell data, text mining and visualization, and the new community collaboration forum. Concurrently, we continue the integration and harmonization of infrastructure, processes, and tools with the Alliance of Genome Resources, of which WormBase is a founding member.
Keywords:
Caenorhabditis elegans
caenorhabditis
nematode
resource
model
database
data
community
software
gene
curation
annotation
research
literature
mining
tools
health
human
platform
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Genetics cover
Genetics
IF:
5.1
Papers:
8.1K
Citations:
3.6W

Organization

C
California Institute of Technology
Scholars:
2.9W
Papers: 2.5W
Citations: 4.9W
European Bioinformatics Institute cover
European Bioinformatics Institute
Scholars:
1.1K
Papers: 604
Citations: 1.4W
E
european molecular biology laboratory (embl)
Scholars:
8.3K
Papers: 5.1K
Citations: 31
W
wellcome trust sanger institute
Scholars:
6.9K
Papers: 4.3K
Citations: 17
O
Ontario Institute for Cancer Research
Scholars:
1.3K
Papers: 690
Citations: 4.6K
researcher View more organizations