Not logged in A Novel Unadjuvanted Subunit Respiratory Syncytial Virus Prefusion F Vaccine Induces Potent and Differentiated Functional Immune Responses Compared to AS01-Adjuvanted Arexvy in Older Adults Richmond, Peter; Kwan, Terence T. L.; Rook, Christopher; Sun, Ana; Tan, Wei; Jackson, Nicholas; Ambrosino, Donna; Siber, George; Costa-Clemens, Sue Ann; Clemens, Ralf; Burdin, Nicolas; Liang, Joshua G. Share Save
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Navigating the changing landscape of BTK-targeted therapies for B cell lymphomas and chronic lymphocytic leukaemia Stanchina, Michele D.; Montoya, Skye; Danilov, Alexey V.; Castillo, Jorge J.; Alencar, Alvaro J.; Chavez, Julio C.; Cheah, Chan Y.; Chiattone, Carlos; Wang, Yucai; Thompson, Meghan; Ghia, Paolo; Taylor, Justin; Alderuccio, Juan Pablo Share Save
Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR-1707 in healthy adult subjects: two randomized, double-blind, single-ascending-dose, phase 1 studies Yang, Yaru; Qiu, Hongyan; Fan, Yuru; Zhang, Qin; Qin, Huiling; Wu, Juan; Zhang, Xuan; Liu, Yueyue; Zhou, Renpeng; Zhang, Qian; Ye, Zi; Ma, Jingyue; Xu, Ye; Feng, Sheng; Fei, Yue; Li, Na; Cui, Xiaojing; Dong, Fangli; Wang, Quanren; Shen, Kai; Shakib, Sepehr; Williams, Jasmine; Hu, Wei Share Save
Preliminary safety and anti-tumor activity of TYRA-300, a highly selective FGFR3 inhibitor, in participants with advanced solid tumors with activating FGFR3 mutations/fusions (SURF301) Tran, B.; Boni, A.; Hansen, A.; Boni, V.; Mantia, C.; Yu, E.; Weickhardt, A.; Robert, M.; Gupta, S.; Necchi, A.; Morales-Barrera, R.; Hoimes, C.; Berlin, J.; Iyer, G.; Millward, M.; Burn, T.; Lihou, C.; Gammon, G.; Rosenberg, J.; Loriot, Y. Share Save
A signal-seeking phase 2 study of Trastuzumab emtansine in tumours harbouring HER2 amplification or mutation Thavaneswaran, Subotheni; Lin, Frank; Grady, John P.; Espinoza, David; Huang, Min Li; Chinchen, Sarah; Sebastian, Lucille; Kansara, Maya; Mersiades, Tony; Lee, Chee Khoon; Desai, Jayesh; Grimison, Peter; Brown, Michael; Millward, Michael; Harrup, Rosemary; O'Byrne, Ken; Nagrial, Adnan; Craft, Paul; Simes, John; Joshua, Anthony M.; Thomas, David M. Share Save
Tucatinib and trastuzumab in advanced cancers with HER2 mutations or amplification: A molecular screening and therapeutics (MoST) program substudy Kong, B. Y.; Lin, F. P-Y.; Espinoza, D.; Thavaneswaran, S.; Meniawy, T.; Desai, J.; Harrup, R.; Selva-Nayagam, S.; Charakidis, M.; Cuff, K.; Sebastian, L.; Lee, C. K.; Chinchen, S.; Thomas, D. M.; Ballinger, M. L.; Simes, J.; Goldstein, D. Share Save
Results from the first-in-human study of ATR inhibitor, IMP9064 monotherapy dose escalation in patients with advanced solid tumors Lin, C-C.; Schneider, R.; Gutierrez, M.; Shen, L.; Chung, K.; Doroshow, D. B.; Gao, B.; Millward, M.; Hsieh, C-Y.; Xu, C.; Cai, S. X.; Tian, Y. E.; Liu, L.; Shen, C.; Tan, Y.; He, Y.; Zhang, C.; Li, L.; Ma, M.; Xu, L. Share Save
Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2) Davar, Diwakar; Cavalcante, Ludimila; Lakhani, Nehal; Moser, Justin; Millward, Michael; Mckean, Meredith; Voskoboynik, Mark; Sanborn, Rachel E.; Grewal, Jaspreet S.; Narayan, Ajita; Patnaik, Amita; Gainor, Justin F.; Sznol, Mario; Enstrom, Amanda; Blanchfield, Lori; Leblanc, Heidi; Thomas, Heather; Chisamore, Michael J.; Peng, Stanford L.; Naumovski, Allison Share Save
A phase I randomized study to evaluate safety, pharmacokinetics, and pharmacodynamics of SIR2446M, a selective RIPK1 inhibitor, in healthy participants Sun, Ana Liza Andresan; Gillies, John David; Shen, Yang; Deng, Huajun; Xue, Fenchao; Ma, Yongfen; Song, Linan Share Save
Evaluating Debio 1347 in Patients with FGFR Fusion-Positive Advanced Solid Tumors from the FUZE Multicenter, Open-Label, Phase II Basket Trial Grivas, Petros; Garralda, Elena; Meric-Bernstam, Funda; Mellinghoff, Ingo K.; Goyal, Lipika; Harding, James J.; Dees, E. Claire; Bahleda, Rastislav; Azad, Nilofer S.; Karippot, Asha; Kurzrock, Razelle; Tabernero, Josep; Kononen, Juha; Ng, Matthew C. H.; Mehta, Rutika; Uboha, Nataliya V.; Bigot, Frederic; Boni, Valentina; Bowyer, Samantha E.; Breder, Valeriy; Cervantes, Andres; Chan, Nancy; Cleary, James M.; Dhawan, Mallika; Eefsen, Rikke L.; Ewing, James; Graham, Donna M.; Guren, Tormod K.; Won Kim, Jin; Koynov, Krassimir; Oh, Do-Youn; Redman, Rebecca; Yen, Chia-Jui; Spetzler, David; Roubaudi-Fraschini, Marie-Claude; Nicolas-Metral, Valerie; Ait-Sarkouh, Rafik; Zanna, Claudio; Ennaji, Abdallah; Pokorska-Bocci, Anna; Flaherty, Keith T. Share Save
A phase Ib study of HMBD-001, a monoclonal antibody targeting HER3, with or without chemotherapy in patients with genetic aberrations in HER3 signaling Pavlakis, N.; Millward, M.; Richardson, G.; Andelkovic, V.; Kichenadasse, G.; Thomas, D. M.; Fernandez, A. Mas; Thakkar, D.; Arbabzade, T.; Goey, C. H.; Seet, Q.; Toy, W.; Paszkiewicz, K.; Ingram, P. J.; Boyd-Kirkup, J. D.; Kwek, K. Y. Share Save
A phase 1a/1b first-in-human study (COMPASSION-01) evaluating cadonilimab in patients with advanced solid tumors Frentzas, Sophia; Gan, Hui K.; Cosman, Rasha; Coward, Jermaine; Tran, Ben; Millward, Michael; Zhou, Yiting; Wang, Wenjing; Xia, Dennis; Wang, Zhongmin Maxwell; Li, Baiyong; Xia, Michelle; Desai, Jayesh Share Save
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AXA-042, a systemically administered TLR2/6 agonist, demonstrates target engagement and TLR pathway activation in patients with advanced solid tumors Tran, B.; Millward, M.; Lemech, C.; Frentzas, S.; Day, D.; Latifi, A.; Desai, J.; Wabnitz, P.; Kearney, P.; Galkin, A. Share Save
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