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梁

梁广 (Guang Liang)

Wenzhou Medical University

64H-index
477Paper Count
1.4WCitation Count
Published Papers 252
Publication Date
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A novel strategy for stabilizing the β-catenin destruction complex: Phillygenin targets AXIN1–Dvl interaction to inhibit triple-negative breast cancer
errActa Pharmaceutica Sinica B
IF14.6
err2026-10-01
err0
errOAAI
errXiaohong Deng; Jie Yu; Wenhui Li; Chengkai Zhu; Shijie Hu; Yi Zhang; Guang Liang; Jingnan Zhang
errShare
errSave
Compound J27 alleviates obesity-induced cardiomyopathy by targeting JNK2
errInternational Immunopharmacology
IF4.7
err2026-08-01
err0
PREAI
errDong, Hui; Wang, Ao; Ye, Jiaxi; Qiao, Liman; Yao, Xia; Cui, Yaqian; Lin, Mengsha; Xiong, Yongqiang; Jin, Leiming; Yang, Yudie; Guo, Xiaochen; Luo, Wu; Liang, Guang; Zhu, Hong; Zhu, Weiwei
errShare
errSave
Eupalinolide B ameliorates liver fibrosis by targeting PKCα to suppress the AKT/mTOR axis in hepatic stellate cells
errJournal of Ethnopharmacology
IF5.4
err2026-02-26
err0
PREAI
errAo Wang; Hui Dong; Yaqian Cui; Yongqiang Xiong; Leiming Jin; Qianhui Zhang; Weiwei Zhu; Jiaxi Ye; Mengsha Lin; Wu Luo; Guang Liang; Jinfeng Sun
errShare
errSave
Lycorine improves inflammatory imbalance in diabetic cardiomyopathy by targeting ILF3
errPhytomedicine
IF8.3
err2026-02-14
err0
PREAI
errQian Zhou; Xuejin Jin; Miao Yuan; Huanyan Tao; Shenjie Bao; Jingnan Zhang; Zheng Xu; Nipon Chattipakorn; Yi Wang; Hong Zhu; Guang Liang
errShare
errSave
Synthesis and Structural Characterization of an Ibrutinib Intermediate Derivative: A Comprehensive Experiment for Undergraduate Students of Medicinal Chemistry
errJournal of Chemical Education
IF2.9
err2026-01-01
err0
PREAI
errZeng, Shenxin; Li, Jun; Yu, Sisi; Chen, Xiaolin; Wang, Jian; Liang, Guang; Du, Wenting
errShare
errSave
Retraction notice to “Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells” [Redox Biology 21 (2019) 101061]
errRedox Biology
IF11.9
err2025-12-17
err0
errOAAI
errXi Chen; Xiaoming Chen; Xi Zhang; Li Wang; Peihai Cao; Vinothkumar Rajamanickam; Chao Wu; Huiping Zhou; Yuepiao Cai; Guang Liang; Yi Wang
errShare
errSave
JOSD2 alleviates hypertensive renal disease through deubiquitinating AKT in renal tubular epithelial cells
errCellular Signalling
IF3.7
err2025-12-16
err0
PREAI
errShijie Fan; Ying Zhao; Luyao Li; Qingqing Zhao; Ziming Fang; Diyun Xu; Jingjing Shao; Yunjie Zhao; Guang Liang; Xuelin He; Hong Zhu; Yi Wang
errShare
errSave
OTUD6A drives dopaminergic neuronal degeneration of Parkinson’s disease through deubiquitinating ACTG1 in neuronal cells
errActa Pharmaceutica Sinica B
IF14.6
err2025-12-03
err0
errOAAI
errXia Zhao; Fan Chen; Li Xiong; Xiaoxia Xu; Ziyao Meng; Yu Deng; Qi Ai; Luyao Li; Qin Yu; Linjie Chen; Ruya Wang; Yiyu Ren; Wenhua Zheng; Jurui Wei; Houming Yu; Guang Liang
errShare
errSave
Isolinderalactone attenuates atherosclerosis through inhibiting NF-κB-mediated inflammation in macrophages
errInternational Immunopharmacology
IF4.7
err2025-11-17
err0
PREAI
errYudie Yang; Sirui Shen; Yue Guan; Xiaochen Guo; Mengsha Lin; Hui Dong; Leiming Jin; Yaqian Cui; Mincong Huang; Guang Liang; Weiwei Zhu; Xiang Hu; Wu Luo
errShare
errSave
Deubiquitinating enzymes in parkinson’s disease: molecular mechanisms and therapeutic potential
errMolecular Medicine
IF6.4
err2025-11-07
err0
errOAAI
errYarong Wu; Yu Deng; Qi Ai; Yingzhou Li; Feiya Qin; Muzaffar Hammad; Ziyao Meng; Xiaoxia Xu; Jurui Wei; Houming Yu; Guang Liang; Xia Zhao
errShare
errSave
A Low-Complexity SBL-Based Method for 2-D DOA Estimation with Two L-Shaped Arrays
errCircuits Systems and Signal Processing
IF2
err2025-11-01
err0
PREAI
errYang, Jie; Ma, Jingtao; Liang, Guang; Gong, Wenbin
errShare
errSave
EP.17.18 Refining Lung Cancer Diagnosis Through Multidisciplinary Team Collaboration
errJournal of Thoracic Oncology
IF20.8
err2025-10-23
err0
PREAI
errX. Zhang; C. He; G. Liang; K. Ye; L. Kang; C. Shi; P. Cui; H. Wang
errShare
errSave
Discovery of Benzodiazepinepyrimidine Scaffold Derivatives as Potent Doublecortin-Like Kinase 1 (DCLK1) Inhibitors for the Treatment of Acute Inflammatory Diseases
errJournal of Medicinal Chemistry
IF6.8
err2025-10-07
err0
PREAI
errShanchao Wu; Lei Wang; Yingqi Song; Changlu Li; Xiaoyao Lu; Qingwei Bu; Keliang Li; Yuping Chen; Hua Sun; Guang Liang; Gaozhi Chen; Chunquan Sheng
errShare
errSave
Gigantol: a principal bioactive constituent of Dendrobium species—multi-target mechanisms, network pharmacology, and therapeutic perspectives
errJournal of Ethnopharmacology
IF5.4
err2025-09-10
err0
PREAI
errSha Shi; Chengkai Zhu; Jiaqi Xu; Qi Sui; Shanhao Zhu; Jingnan Zhang; Peng Chen; Guang Liang; Yi Zhang
errShare
errSave
Deubiquitinase JOSD2 promotes acute pancreatitis by removing K63-linked poly-ubiqutin chain on PCNA in pancreatic acinar cells
errCellular and Molecular Gastroenterology and Hepatology
IF7.4
err2025-09-02
err0
errOAAI
errYi Fang; Xiang Hu; Lijun Ji; Jiaxi Ye; Yaqian Cui; Yongqiang Xiong; Tianyang Jing; Qingsong Zheng; Guang Liang; Xin Liu; Wu Luo
errShare
errSave
β-elemene ameliorates metabolic dysfunction-associated steatohepatitis by targeting PPARα in experimental diet-induced models
errBritish Journal of Pharmacology
IF7.7
err2025-08-07
err0
PREAI
errYongqiang Xiong; Wu Luo; Jiaxi Ye; Yaqian Cui; Xiangsheng Zheng; Leiming Jin; Shuaijie Lou; Qianhui Zhang; Ao Wang; Yi Fang; Tianyang Jin; Mengsha Lin; Hui Dong; Guang Liang; Xiang Hu; Weiwei Zhu
errShare
errSave
Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction
errNature Communications
IF15.7
err2025-07-19
err0
errOAAI
errXue Han; Ruyi Zheng; Jiajia Zhang; Yanan Liu; Ze Li; Guoxuan Liu; Jianing Zheng; Weiqi Li; Zijun Liang; Mengyang Wang; Jie Yu; Qiaojuan Shi; Huazhong Ying; Guang Liang
errShare
errSave
Myeloid MyD88 Mediates Macrophage Infiltration and Activation in Ang II-Induced Cardiac Hypertrophy
errJournal of Cellular and Molecular Medicine
IF4.2
err2025-07-19
err0
errOAAI
errKe Lin; Na Yang; Chenghong Hu; Wu Luo; Ping Huang; Guang Liang; Yi Wang
errShare
errSave
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2
errClinical and Translational Medicine
IF6.8
err2025-07-18
err0
errOAAI
errXia Zhao; Jinfeng Sun; Fan Chen; Hao Tang; Yuqing Zeng; Luyao Li; Qin Yu; Linjie Chen; Muzaffar Hammad; Xiaoxia Xu; Ziyao Meng; Wei Wang; Guang Liang
errShare
errSave
Cardiomyocyte-derived USP13 protects hearts from hypertrophy via deubiquitinating and stabilizing STAT1 in male mice
errNature Communications
IF15.7
err2025-07-01
err0
errOAAI
errJibo Han; Liming Lin; Zimin Fang; Diyun Xu; Lintao Wang; Bozhi Ye; Xue Han; Xiaohong Long; Julian Min; Gaojun Wu; Guang Liang; Yi Wang
errShare
errSave

Research Directions

代谢性疾病并发症机制与新药研发
Co-authors
Cooperation Journals
C
Carlo M. Croce
H-index: 209 · Papers: 1.8K
卫
卫敏 (Min Wei)
H-index: 109 · Papers: 564
J
James L. Boyer
H-index: 93 · Papers: 486
M
Moosa Mohammadi
H-index: 91 · Papers: 681
S
Shaoming Huang
H-index: 91 · Papers: 698
View more