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D

David Needham

duke university

65H-index
225Paper Count
1.8WCitation Count
Published Papers 70
Publication Date
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Novel niclosamide stearate prodrug therapeutic shows potential efficacy against naturally occurring canine osteosarcoma in a clinical feasibility study
errAmerican Journal of Veterinary Research
IF1.4
err2026-01-01
err1
PREAI
errEward, William C.; Pavic, Kristina; Spasojevic, Ivan; Somarelli, Jason A.; Brighton, Hailey; Cullen, Mark; Jung, Sin-Ho; Visgauss, Julia D.; Brigman, Brian E.; Needham, David; Suter, Steven E.
errShare
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Tumor Ablation and Immune Microenvironment Modulation Following Laser Interstitial Thermal Therapy in a Murine Glioblastoma Model
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errPuentes, Ashley; Athukuri, Prazwal; Moreno, Karina; Yang, Yuhui; Mcdonald, Malcolm; Marisetty, Anantha; Lee, Sungho; Latha, Khatri; Needham, David; Rao, Ganesh
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LDLR-targeted orlistat therapeutic nanoparticles: Peptide selection, assembly, characterization, and cell-uptake in breast cancer cell lines
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2025-05-01
err0
errOAAI
errBebawy, George; Collier, Pamela; Williams, Philip M.; Burley, Jonathan C.; Needham, David
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errSave
LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-04-06
err20
errOAAI
errDickinson, Mary S.; Kutsch, Miriam; Sistemich, Linda; Hernandez, Dulcemaria; Piro, Anthony S.; Needham, David; Lesser, Cammie F.; Herrmann, Christian; Coers, Joern
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errSave
Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery
errPHARMACEUTICS
IF5.5
err2023-02-10
err3
errOAAI
errAdekeye, Adenike O.; Needham, David; Rahman, Ruman
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errSave
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections
errPHARMACEUTICAL RESEARCH
IF4.3
err2021-12-28
err15
errOAAI
errNeedham, David
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errSave
Inhibition of the futalosine pathway for menaquinone biosynthesis suppresses Chlamydia trachomatis infection
errFEBS LETTERS
IF3
err2021-11-16
err4
errOAAI
errDudiak, Brianne M.; Nguyen, Tri M.; Needham, David; Outlaw, Taylor C.; McCafferty, Dewey G.
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errSave
Designing topographically textured microparticles for induction and modulation of osteogenesis in mesenchymal stem cell engineering
errBIOMATERIALS
IF12.9
err2021-01-01
err33
errOAAI
errAmer, Mahetab H.; Alvarez-Paino, Marta; McLaren, Jane; Pappalardo, Francesco; Trujillo, Sara; Wong, Jing Qian; Shrestha, Sumana; Abdelrazig, Salah; Stevens, Lee A.; Lee, Jong Bong; Kim, Dong-Hyun; Gonzalez-Garcia, Cristina; Needham, David; Salmeron-Sanchez, Manuel; Shakesheff, Kevin M.; Alexander, Morgan R.; Alexander, Cameron; Rose, Felicity R. A. J.
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errSave
Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2020-07-02
err17
errOAAI
errReddy, Gireesh B.; Kerr, David L.; Spasojevic, Ivan; Tovmasyan, Artak; Hsu, David S.; Brigman, Brian E.; Somarelli, Jason A.; Needham, David; Eward, William C.
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errSave
Polymer Microparticles with Defined Surface Chemistry and Topography Mediate the Formation of Stem Cell Aggregates and Cardiomyocyte Function
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2019-06-20
err24
errOAAI
errAlvarez-Paino, Marta; Amer, Mahetab H.; Nasir, Aishah; Crucitti, Valentina Cuzzucoli; Thorpe, Jordan; Burroughs, Laurence; Needham, David; Denning, Chris; Alexander, Morgan R.; Alexander, Cameron; Rose, Felicity R. A. J.
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errSave
Oleogelating properties of ethylcellulose in oil-in-water emulsions: The impact of emulsification methods studied by 13C MAS NMR, surface tension and micropipette manipulation studies
errFOOD HYDROCOLLOIDS
IF12.4
err2019-04-01
err24
errOAAI
errMunk, Merete B.; Utoft, Anders; Larsen, Flemming H.; Needham, David; Risbo, Jens
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errSave
Micro-Surface and -Interfacial Tensions Measured Using the Micropipette Technique: Applications in Ultrasound-Microbubbles, Oil-Recovery, Lung-Surfactants, Nanoprecipitation, and Microfluidics
errMICROMACHINES
IF3
err2019-02-01
err15
errOAAI
errNeedham, David; Kinoshita, Koji; Utoft, Anders
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errSave
Chelation, formulation, encapsulation, retention, and in vivo biodistribution of hydrophobic nanoparticles labelled with 57Co-porphyrin: Oleylamine ensures stable chelation of cobalt in nanoparticles that accumulate in tumors
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2018-12-01
err9
errOAAI
errHervella, Pablo; Dam, Johan Hygum; Thisgaard, Helge; Baun, Christina; Olsen, Birgitte Brinkmann; Hoilund-Carlsen, Poul Flemming; Needham, David
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errSave
Manipulating Single Microdroplets of NaCI Solutions: Solvent Dissolution, Microcrystallization, and Crystal Morphology
errLANGMUIR
IF3.9
err2018-03-06
err15
errOAAI
errUtoft, Anders; Kinoshita, Koji; Bitterfield, Deborah L.; Needham, David
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errSave
Adsorption of ionic surfactants at microscopic air-water interfaces using the micropipette interfacial area-expansion method: Measurement of the diffusion coefficient and renormalization of the mean ionic activity for SDS
errJOURNAL OF COLLOID AND INTERFACE SCIENCE
IF9.7
err2017-10-01
err27
PREAI
errKinoshita, Koji; Parra, Elisa; Needham, David
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errSave
Real-Time Visualization of the Precipitation and Phase Behavior of Octaethylporphyrin in Lipid Microparticles
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2017-04-01
err4
PREAI
errParra, Elisa; Hervella, Pablo; Needham, David
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errSave
HEAT-TARGETED DRUG DELIVERY USING THE COMBAT BRS DEVICE FOR TREATING BLADDER CANCER
errJOURNAL OF UROLOGY
IF6.8
err2017-04-01
err4
errOAAI
errBrousell, Steven C.; Longo, Thomas A.; Fantony, Joseph J.; Etienne, Wiguins; Needham, David; Dewhirst, Mark W.; Maccarini, Paolo F.; Spasojevic, Ivan; Inman, Brant A.
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errSave
New sensitive micro-measurements of dynamic surface tension and diffusion coefficients: Validated and tested for the adsorption of 1-Octanol at a microscopic air-water interface and its dissolution into water
errJOURNAL OF COLLOID AND INTERFACE SCIENCE
IF9.7
err2017-02-01
err31
errOAAI
errKinoshita, Koji; Parra, Elisa; Needham, David
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errSave
An Activity-Based Dissolution Model for Solute-Containing Microdroplets
errLANGMUIR
IF3.9
err2016-11-14
err11
PREAI
errBitterfield, Deborah L.; Utoft, Anders; Needham, David
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errSave
Micropipette Technique Study of Natural and Synthetic Lung Surfactants at the Air-Water Interface: Presence of a SP-B Analog Peptide Promotes Membrane Aggregation, Formation of Tightly Stacked Lamellae, and Growth of Myelin Figures
errLANGMUIR
IF3.9
err2016-10-03
err9
PREAI
errParra, Elisa; Kinoshita, Koji; Needham, David
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
H
Hope S. Rugo
H-index: 137 · Papers: 1.6K
M
Mark W. Dewhirst
H-index: 120 · Papers: 1.0K
A
Ashutosh Chilkoti
H-index: 106 · Papers: 473
H
Hagan Bayley
H-index: 103 · Papers: 448
S
Silvia C. Formenti
H-index: 89 · Papers: 673
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