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F

Frank J. Gonzalez

national cancer institute

191H-index
1.7KPaper Count
15.0WCitation Count
Published Papers 777
Publication Date
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Pulsatile FXR activation: Timing bile acid-targeted therapy to physiology
errActa Pharmacologica Sinica
IF8.4
err2026-07-29
err0
PREAI
errTing-ying Jiao; Yang-tai Li; Frank J. Gonzalez; Cen Xie
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Dietary fat alters goblet cell function and microbial bile acid metabolism to promote intestinal lipid absorption in mice
errNature Microbiology
IF19.4
err2026-06-10
err0
PREAI
errXinyu Liang; Yongxin Zhang; Wei Xie; Jiayi Xiong; Suqin Lin; Yingquan Wen; Yutang Cao; Shuwu Yu; Kanglong Wang; Jie Deng; Jingjie Zhao; Jingyi Xu; Yiyang Hu; Yameng Liu; Qin Feng; Yifei Zhong; Frank J. Gonzalez; Cen Xie
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errSave
FXR’s double life in bile ducts
errNature Metabolism
IF20.8
err2026-04-28
err0
PREAI
errShogo Takahashi; Frank J. Gonzalez
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errSave
Loss of SALL1 Promotes Hepatocellular Carcinoma Growth and Is Associated with Poor Clinical Outcome
errCancers
IF4.4
err2026-04-27
err0
errOAAI
errYoshifumi Saito; Carlos Ichiro Kasano-Camones; Atsumi Tamura; Shioko Kimura; Xiaoting Yu; Yutong Cui; Vorthon Sawaswong; Kristopher W. Krausz; Dong Wang; Aijuan Qu; Yusuke Inoue; Shogo Takahashi; Frank J. Gonzalez
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errSave
Ketogenic diet exacerbates DSS-induced colitis through a β-hydroxybutyrate-Thomasclavelia spiroformis-γδ17 T cell axis in mice
errNature Communications
IF15.7
err2026-04-23
err0
errOAAI
errYameng Liu; Xuan Wu; Li Chen; Shan Wang; Jingyi Xu; Weifeng Wang; Xueting Yao; Wei Xie; Xianchun Zhong; Shuai Li; Yueying Li; Lin Han; Cen Xie; Lei Chen; Frank J. Gonzalez; Weiwei Liu
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errSave
Proximal Tubule-Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting
errFASEB JOURNAL
IF4.2
err2025-12-29
err0
errOAAI
errAomura, Daiki; Nimura, Takayuki; Yamaka, Kosuke; Yamada, Yosuke; Harada, Makoto; Nakajima, Takero; Kimura, Takefumi; Hashimoto, Koji; Kanno, Hiroyuki; Yanagita, Motoko; Gonzalez, Frank J.; Tanaka, Naoki; Kamijo, Yuji
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errSave
Role of the xenobiotic-activated pregnane X receptor in type 1 and type 2 diabetes in male mice
errBiochemical Pharmacology
IF5.6
err2025-10-29
err0
PREAI
errDaniel Okwudili Nnamani; Sora Choi; Malvin Ofosu-Boateng; Lidya H. Gebreyesus; Elizabeth Twum; Marianne Polunas; Michael Goedken; Nour Yadak; Samuel Dagogo-Jack; Rexford S. Ahima; Susan T. Yeyeodu; Frank J. Gonzalez; Maxwell A. Gyamfi
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Sirtuin 6 mitigates thoracic aortic aneurysm progression via maintenance of mitochondria homeostasis in vascular smooth muscle cells
errActa Pharmacologica Sinica
IF8.4
err2025-09-02
err0
PREAI
errXiao-ting Yu; Nan Zhao; Yu-tao Ma; Jin-meng Jia; Yan-ting Song; Xiao-yan Liu; Yao Xiao; Bo Jia; Guang-ming Li; Jin-han He; Sheng Wang; Jun-ming Zhu; Frank J. Gonzalez; Ai-juan Qu
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errSave
Role of Metabolic Nuclear Receptors in Acute Liver Injury and Drug-Induced Hepatotoxicity
errPharmacological Research
IF10.5
err2025-09-02
err0
errOAAI
errLiangliang Nie; Nana Yan; Frank J. Gonzalez; Haiping Hao; Tingting Yan
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errSave
Human PXR Signaling Exacerbates Ethanol-Induced Liver Injury in Females: Evidence from Mouse Models and Human ALD Cohorts
errCellular and Molecular Gastroenterology and Hepatology
IF7.4
err2025-07-16
err0
errOAAI
errMalvin Ofosu-Boateng; Sora Choi; Sarah Kim; Elizabeth Twum; Daniel O. Nnamani; Lidya H. Gebreyesus; Suryakant Niture; Nour Yadak; Deepak Kumar; Frank J. Gonzalez; Suthat Liangpunsakul; Julia Yue Cui; Maxwell A. Gyamfi
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errSave
Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression
errCell Metabolism
IF30.9
err2025-07-02
err0
PREAI
errRuize Qu; Yi Zhang; Bora Kim; Guangyi Zeng; Pengcheng Wang; Weike Shaoyong; Ying Huang; Wanwan Guo; Yang Chen; Ping Wang; Qing Yang; Siyi Lu; Xin Zhou; Jing Weng; Jinkun Xu; Jun Lin; Kai Wang; Yanpeng Ma; Shogo Takahashi; Yuhong Luo; Xiaoting Yu; Kristopher W. Krausz; Yanli Pang; Tianpei Hong; Zhipeng Zhang; Wei Fu; Frank J. Gonzalez; Lulu Sun
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errSave
Farnesoid X receptor regulates CYP1A1 and CYP1B1 and estradiol metabolism in mouse and human cell lines
errCHEMICO-BIOLOGICAL INTERACTIONS
IF5.4
err2025-05-01
err0
PREAI
errChen, Chanjuan; Lin, Pei; Wu, Zubao; Lin, Yihan; Huang, Meixia; He, Liangliang; Yao, Xinsheng; Gonzalez, Frank J.; Qin, Zifei; Yao, Zhihong
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Publisher erratum to “Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway” [Acta Pharmaceutica Sinica B 14 (2024) 2992–3008]
errActa Pharmaceutica Sinica B
IF14.6
err2025-04-16
err0
errOAAI
errShicheng Fan; Yue Gao; Pengfei Zhao; Guomin Xie; Yanying Zhou; Xiao Yang; Xuan Li; Shuaishuai Zhang; Frank J. Gonzalez; Aijuan Qu; Min Huang; Huichang Bi
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errSave
Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-03-01
err0
PREAI
errKhan, Yahya; Schmidt, Annalee M.; Oldro, Kyle J.; Zhu, Xiaoyang; Kramer, Angelina R.; Hamilton, Sarah R.; Bleil, Katherine O.; Krisko, Ryan M.; Zitzow, Jeremiah D.; Tian, Yuan; Chang, Shu-Ching; Walter, Vonn; Cohen, Samuel M.; Gonzalez, Frank J.; Patterson, Andrew D.; Peters, Jeffrey M.
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Superoxide is an Intrinsic Signaling Molecule Triggering Muscle Hypertrophy
errANTIOXIDANTS & REDOX SIGNALING
IF6.1
err2025-01-01
err1
PREAI
errLu, Siyu; Zhou, Yiming; Liu, Mincong; Gong, Lijun; Liu, Li; Duan, Zhigui; Chen, Keke; Gonzalez, Frank J.; Wei, Fang; Xiang, Rong; Li, Guolin
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Hepatocyte-specific SLC27A4 deletion ameliorates nonalcoholic fatty liver disease in mice via suppression of phosphatidylcholine-mediated PXR activation
errMETABOLISM-CLINICAL AND EXPERIMENTAL
IF11.9
err2025-01-01
err0
PREAI
errShen, Chuangpeng; Pan, Zhisen; Xie, Wenmin; Zhao, Jian; Miao, Deyu; Zhao, Ling; Liu, Min; Zhong, Yanhua; Zhong, Chong; Gonzalez, Frank J.; Wang, Wei; Gao, Yong; Liu, Changhui
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errSave
Associations of chronic liver disease and liver cancer with glyphosate and its metabolites in Thailand
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2024-12-09
err1
errOAAI
errPatel, Daxesh P.; Loffredo, Christopher A.; Pupacdi, Benjarath; Rabibhadana, Siritida; Navasumrit, Panida; Chaisaingmongkol, Jittiporn; Toulabi, Leila; Haznadar, Majda; Dalal, Bhavik; Khan, Mohammed; Stone, Joshua; Bhudhisawasdi, Vajarabhongsa; Lertprasertsuke, Nirush; Chotirosniramit, Anon; Pairojkul, Chawalit; Auewarakul, Chirayu U.; Sricharunrat, Thaniya; Phornphutkul, Kannika; Sangrajrang, Suleeporn; Budhu, Anuradha; Mahidol, Chulabhorn; Wang, Xin W.; Gonzalez, Frank J.; Ruchirawat, Mathuros; Harris, Curtis C.; TIGER-LC Consortium
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Intestinal stearoyl-coenzyme A desaturase-inhibition improves obesity-associated metabolic disorders
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-12-01
err0
errOAAI
errXia, YL; Zhang, Y; Zhang, ZP; Yan, NN; Sawaswong, V; Sun, LL; Guo, WW; Wang, P; Krausz, KW; Gavrilova, O; Ntambi, JM; Hao, HP; Yan, TT; Gonzalez, FJ
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errSave
E2F3a activates Gadd45b gene expression through PPARα-mediated transcriptional regulation in hepatic cells
errMOLECULES AND CELLS
IF6.5
err2024-12-01
err0
errOAAI
errWoo, Min Seok; Khalil, Atif Ali Khan; Gonzalez, Frank J.; Kim, Jung-Hwan
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errSave
Human CYP2D6 varies across the estrous cycle in brains of transgenic mice altering drug response
errPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
IF3.9
err2024-12-01
err0
PREAI
errMiksys, Sharon; McDonald, Claire; Wadji, Fariba Baghai; Gonzalez, Frank J.; Tyndale, Rachel F.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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H-index: 170 · Papers: 569
B
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H-index: 167 · Papers: 1.2K
C
C. Ronald Kahn
H-index: 164 · Papers: 635
J
John N. Weinstein
H-index: 163 · Papers: 987
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