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S

Sjors H. W. Scheres

medical research council

84H-index
354Paper Count
5.0WCitation Count
Published Papers 82
Publication Date
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The amyloid packing difference: A pairwise comparison metric for amyloid structures
errStructure
IF4.3
err2026-05-22
err0
errOAAI
errSjors H.W. Scheres
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Seeding biosensor cell line that reproduces the Alzheimer tau fold
errJournal of Biological Chemistry
IF3.9
err2025-11-17
err0
errOAAI
errTaxiarchis Katsinelos; Sofia Lövestam; Chao Qi; Benjamin Ryskeldi-Falcon; Jennifer A. Macdonald; Gabriel Stephenson; Bernardino Ghetti; Ann McKee; Sjors H.W. Scheres; Michel Goedert
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Author Correction: Structures of α-synuclein filaments from multiple system atrophy
errNature
IF48.5
err2025-10-22
err0
errOAAI
errManuel Schweighauser; Yang Shi; Airi Tarutani; Fuyuki Kametani; Alexey G. Murzin; Bernardino Ghetti; Tomoyasu Matsubara; Taisuke Tomita; Takashi Ando; Kazuko Hasegawa; Shigeo Murayama; Mari Yoshida; Masato Hasegawa; Sjors H. W. Scheres; Michel Goedert
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Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
errNature Communications
IF15.7
err2025-10-17
err0
errOAAI
errAlysa Kasen; Sofia Lövestam; Libby Breton; Lindsay Meyerdirk; Jacob Alec McPhail; Kristin Piche; Ariel Louwrier; Colt D. Capan; Hyoungjoo Lee; Sjors H. W. Scheres; Michael X. Henderson
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Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau
errFEBS LETTERS
IF3
err2025-09-01
err0
errOAAI
errSantambrogio, Alessia; Lovestam, Sofia; Metrick II, Michael A.; Lohr, Thomas; Xu, Peifeng; Gallagher, Nicholas C. T.; Ghetti, Bernardino; Caughey, Byron; Scheres, Sjors H. W.; Vendruscolo, Michele
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Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps
errStructure
IF4.3
err2025-08-12
err0
errOAAI
errSofia Lövestam; Sjors H.W. Scheres
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Identical Seeding Characteristics and Cryo-EM Filament Structures in FTLD-Synuclein and Typical Multiple System Atrophy
errNEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
IF3.4
err2025-04-01
err0
errOAAI
errCullinane, Patrick W.; Yang, Yang; Chelban, Viorica; Goh, Yee Yen; Ebanks, Kirsten; Curless, Toby; Wrigley, Sarah; de Pablo-Fernandez, Eduardo; Holton, Janice; Peak-Chew, Sew; Franco, Catarina; Woerman, Amanda L.; Houlden, Henry; Warner, Thomas T.; Scheres, Sjors H. W.; Goedert, Michel; Jaunmuktane, Zane
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Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2025-03-05
err1
errOAAI
errQi, Chao; Loevestam, Sofia; Murzin, Alexey G.; Peak-Chew, Sew; Franco, Catarina; Bogdani, Marika; Latimer, Caitlin; Murrell, Jill R.; Cullinane, Patrick W.; Jaunmuktane, Zane; Bird, Thomas D.; Ghetti, Bernardino; Scheres, Sjors H. W.
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Driving Tau Pathogenicity Seeding - How Fibril Structure and Post-Translational Modifications Alter Seeding Capacity
errALZHEIMERS & DEMENTIA
IF11.1
err2025-01-09
err0
errOAAI
errKasen, A; Breton, L; Meyerdirk, L; Lövestam, S; Mcphail, J; Louwrier, A; Scheres, S; Henderson, M
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errSave
TMEM106B amyloid filaments in the Biondi bodies of ependymal cells
errACTA NEUROPATHOLOGICA
IF9.3
err2024-11-06
err1
errOAAI
errGhetti, Bernardino; Schweighauser, Manuel; Jacobsen, Max H.; Gray, Derrick; Bacioglu, Mehtap; Murzin, Alexey G.; Glazier, Bradley S.; Katsinelos, Taxiarchis; Vidal, Ruben; Newell, Kathy L.; Gao, Sujuan; Garringer, Holly J.; Spillantini, Maria Grazia; Scheres, Sjors H. W.; Goedert, Michel
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DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images
errNATURE METHODS
IF32.1
err2024-08-09
err5
errOAAI
errSchwab, Johannes; Kimanius, Dari; Burt, Alister; Dendooven, Tom; Scheres, Sjors H. W.
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Alzheimer's plaques and tangles revealed by 3D microscopy
errNATURE
IF48.5
err2024-07-10
err1
PREAI
errScheres, Sjors H. W.
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Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-06-17
err3
errOAAI
errBacioglu, Mehtap; Schweighauser, Manuel; Gray, Derrick; Lovestam, Sofia; Katsinelos, Taxiarchis; Quaegebeur, Annelies; van Swieten, John; Jaunmuktane, Zane; Davies, Stephen W.; Scheres, Sjors H. W.; Goedert, Michel; Ghetti, Bernardino; Spillantini, Maria Grazia
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Data-driven regularization lowers the size barrier of cryo-EM structure determination
errNATURE METHODS
IF32.1
err2024-06-11
err14
errOAAI
errKimanius, Dari; Jamali, Kiarash; Wilkinson, Max E.; Lovestam, Sofia; Velazhahan, Vaithish; Nakane, Takanori; Scheres, Sjors H. W.
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Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G
errACTA NEUROPATHOLOGICA
IF9.3
err2024-05-17
err0
errOAAI
errQi, Chao; Kobayashi, Ryota; Kawakatsu, Shinobu; Kametani, Fuyuki; Scheres, Sjors H. W.; Goedert, Michel; Hasegawa, Masato
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Tau filaments from amyotrophic lateral sclerosis/parkinsonism- dementia complex adopt the CTE fold
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-12-15
err12
errOAAI
errQi, Chao; Verheijen, Bert M.; Kokubo, Yasumasa; Shi, Yang; Tetter, Stephan; Murzin, Alexey G.; Nakahara, Asa; Morimoto, Satoru; Vermulst, Marc; Sasaki, Ryogen; Aronica, Eleonora; Hirokawa, Yoshifumi; Oyanagi, Kiyomitsu; Kakita, Akiyoshi; Falcon, Benjamin Ryskeldi -; Yoshida, Mari; Hasegawa, Masato; Scheres, Sjors H. W.; Goedert, Michel
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Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2023-12-04
err11
errOAAI
errYang, Yang; Murzin, Alexey G.; Peak-Chew, Sew; Franco, Catarina; Garringer, Holly J.; Newell, Kathy L.; Ghetti, Bernardino; Goedert, Michel; Scheres, Sjors H. W.
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Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2023-10-05
err13
errOAAI
errSchweighauser, Manuel; Murzin, Alexey G.; Macdonald, Jennifer; Lavenir, Isabelle; Crowther, R. Anthony; Scheres, Sjors H. W.; Goedert, Michel
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Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere
errSCIENCE ADVANCES
IF12.5
err2023-07-28
err8
errOAAI
errDendooven, Tom; Zhang, Ziguo; Yang, Jing; McLaughlin, Stephen H.; Schwab, Johannes; Scheres, Sjors H. W.; Yatskevich, Stanislau; Barford, David
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Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains
errNEURON
IF15
err2023-07-01
err30
errOAAI
errStern, Andrew M.; Yang, Yang; Jin, Shanxue; Yamashita, Keitaro; Meunier, Angela L.; Liu, Wen; Cai, Yuqi; Ericsson, Maria; Liu, Lei; Goedert, Michel; Scheres, Sjors H. W.; Selkoe, Dennis J.
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Research Directions

No research directions
Co-authors
Cooperation Journals
M
Matthias Mann
H-index: 250 · Papers: 1.4K
D
Dennis J. Selkoe
H-index: 171 · Papers: 674
M
Michel Goedert
H-index: 146 · Papers: 565
K
Klaus Schulten
H-index: 145 · Papers: 718
F
F. Ulrich Hartl
H-index: 133 · Papers: 498
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